HealthDay News — Patients undergoing preoperative peripheral nerve block placement have a similar change in anxiolytic scores when they receive music medicine versus midazolam, according to a study published online July 18 in Regional Anesthesia & Pain Medicine.

Veena Graff, M.D., from the University of Pennsylvania in Philadelphia, and colleagues compared the use of music to midazolam as a preoperative anxiolytic prior to administration of an ultrasound-guided single-injection peripheral nerve block in a randomized controlled study. The anxiolytic effects of intravenous midazolam (1 to 2 mg) were compared to the effects of noise-canceling headphone-delivered music medicine.

The researchers found that both groups had a similar change in State Trait Anxiety Inventory-6 anxiety scores after compared with before the procedure (music group, −1.6; midazolam group, −4.2; P = 0.14; mean difference between groups, −2.5; 95 percent confidence interval, −5.9 to 0.9; P = 0.1). The midazolam group had higher patient satisfaction scores with their procedure experience (P = 0.01); no differences were seen between the groups in physician satisfaction scores with the procedure experience (P = 0.07). Compared with the midazolam group, the music group had higher patient and physician perceptions of difficulties in communication (P = 0.005 and 0.0007, respectively).

“Further studies should be conducted to evaluate whether or not music genre and techniques of music delivery can offset the trend of improved anxiolysis and fewer communication barriers using midazolam,” the authors write.

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