Healthcare professionals see the benefits of prescribing cannabis therapies but report significant knowledge gaps in both recreational and medical cannabis.
Intrathecal injection of pH-responsive nanoparticles containing the neurokinin 1 receptor antagonist, aprepitant, and targeting acidified endosomes of spinal neurons, was found to inhibit induced nociception in rodents.
Among those reporting alcohol use, patients with certain common medical conditions are more likely to report excessive drinking.
In addition to increased medical costs, chronic pain may result in long term consequences, including impaired activities of daily living, cognitive decline and depression.
Adults with traumatic spinal cord injuries have an increased incidence of psychological morbidities and multimorbidity.
Depression is twice as common in patients with chronic pain compared to health subjects, and pain intensity, frequency, and number of locations are linked to depression and anxiety.
Microdiscectomy is superior to nonsurgical care with respect to pain intensity in patients with sciatica lasting more than four months.
Fatigue, anemia, pain, and sleep disorders form part of the prodrome in MS.
Severe vitamin D deficiency was linked to lumbar degenerative disease and low back pain in postmenopausal women.
Strontium89 (Strontium Chloride Sr-89 injection), a radiopharmaceutical indicated for the relief of bone pain in patients with painful skeletal metastases, has been made available by Q BioMed.