HealthDay News — Patients taking opioids before total knee arthroplasty (TKA) may have greater pain after the procedure, according to a study published in the Journal of Bone & Joint Surgery.1

The research included 156 patients (average age, 66 years) who underwent TKA. Of those patients, 23% received at least 1 opioid prescription before their surgery.

The researchers found that mean preoperative Pain Catastrophizing Scale scores were greater among opioid users vs non-users (15.5 vs 10.7 points; P =.006). In adjusted analyses, the researchers found that the opioid group had a mean 6-month reduction in Western Ontario and McMaster Universities Osteoarthritis Index score of 27.0 points, compared with 33.6 points in the non-opioid group (P =.008).

“Patients who used opioids prior to TKA obtained less pain relief from the operation,” the authors write. “Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA.”

Related Articles

Reference

  1. Smith SR, Bido J, Collins JE, Yang H, Katz JN, Losina E. Impact of Preoperative Opioid Use on Total Knee Arthroplasty Outcomes. J Bone Joint Surg Am. 2017;99(10):803-808.