Acute Pain

ACUTE PAIN

Feature Article

Acute Pain

Uncontrolled Gout: An Open Dialogue With Patients

June 24, 2021

Suneet Grewal, MD, provides a deeper insight into the impact of uncontrolled gout on the quality of life of patients and the importance of having an open dialogue.

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woman receiving knee exam, osteoarthritis

Orthopedic Surgery May Not Be More Effective Than Nonsurgical Alternatives

No strong, high-quality evidence shows that many commonly performed elective orthopedic procedures are more effective than nonoperative alternatives.

Bupivacaine and Meloxicam Now Available for Postsurgical Analgesia for Up to 72 Hours

Brian Park, PharmD

Zynrelef is a dual-acting local anesthetic that delivers a fixed-dose combination of bupivacaine, an amide local anesthetic, and meloxicam, an NSAID.

Genetic, Ethnicity-Dependent Factors Predict Variability in Acute Postoperative Patient-Controlled Analgesia

Lauren Biscaldi

Genetic and nongenetic factors should be evaluated when examining factors contributing to variability in acute postoperative opioid use.

NSAIDs Better Than Codeine for Outpatient Postoperative Pain

For adult outpatients, use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with better pain scores and better global assessments.

Single Injection of Ketorolac Reduces Surgical Pain More Effectively Than Opioids

Jessica Nye, PhD

The researchers’ goals were to compare the efficacy and adverse effects of single‐dose intravenous ketorolac for postoperative pain in adults and compare it with placebo or an active comparator.

FDA Rejects IV Tramadol NDA Again for Efficacy, Safety Concerns

Brian Park, PharmD

The Agency does not believe the data support the safety or efficacy of the treatment either as monotherapy or in combination with other analgesics.

Mortality Increased for Racial/Ethnic Minorities With Traumatic Brain Injury

For patients with traumatic brain injury, racial and ethnic minorities have an increased risk for mortality.

No Evidence to Support the Use of Cryotherapy for the Treatment of Acute Ankle Sprain

Jessica Nye, PhD

The potential effectiveness of cryotherapy in the treatment of acute ankle sprain pain, swelling, and range of motion was evaluated in a systematic review of randomized controlled trials.