The PGIC and MSQ were most highly associated with medical decision making among patients receiving CGRP monoclonal antibody therapy for migraine prevention.
Researchers assessed the effect of neuropathic pain and opioid exposure in children receiving treatment for acute lymphoblastic leukemia.
In the Bronchiolitis Follow-up Intervention Trial (BeneFIT) setting, physicians more often determined that Hispanic patients were not appropriate for as-needed follow-up and excluded them from the trial.
Primary care providers should make individual decisions whether to prescribe aspirin based on a benefit-to-risk ratio, not simply age.
The Janus kinase (JAK) inhibitor baricitinib is strongly recommended for patients with severe or critical COVID-19, and sotrovimab is conditionally recommended for nonsevere COVID-19.
The Senza SCS System is a neuromodulation device designed to deliver electrical stimulation using implantable leads and a rechargeable, implantable pulse generator.
Drug holidays after long-term risedronate are associated with a small increase in the risk for hip fracture compared with drug holidays after long-term alendronate.
Insurance coverage for acupuncturist visits increased from 2010 to 2019, but most costs are paid out of pocket.
The latest shipment of 1.1 million COVID-19 vaccines to Rwanda signaled a noteworthy achievement: The COVAX program, a United Nations-backed program providing poorer countries with vaccines.
This study sought to identify predictors of severe pain during wound dressing change.
The FDA has identified 305 cases of dental problems with buprenorphine-containing medicines dissolved in the mouth.
A migraine-specific adaptation of the Mindfulness-Based Cognitive Therapy (MBCT) program does not improve headache-related impairment among patients with migraine, but does result in reduced headache frequency and improved psychological functioning.
Concise drug information for molnupiravir and Paxlovid; the FDA granted Emergency Use to both oral antiviral therapies.
In a Canadian employer screening program, the overall rate of false-positive results using rapid antigen test screens for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is very low.
The revision of the International Classification of Diseases will provide the first comprehensive diagnostic scheme for chronic pain on the basis of biopsychosocial definition of chronic pain.
Combining intrathecal morphine (ITM) and oral gabapentin (GABA) improves pain management in teens undergoing spinal fusion for scoliosis.
Therapeutic aquatic exercise leads to greater pain alleviation in patients with chronic low back pain compared with physical therapy.
Some health care workers who are fully vaccinated and boosted against COVID-19 do not need to quarantine following high-risk exposures.
The incidence of COVID-19 is increased in association with long-term exposure to airborne pollutants.
There is a need to establish evidence-based guidelines for analgesic use among hospitalized patients with cirrhosis.
A multicomponent strategy provider intervention can increase initiation of buprenorphine treatment for opioid use disorder in the emergency department.
Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients.
Researchers conducted a study to determine the safety and efficacy of the Ad5-nCoV vaccine for protection against SARS-CoV-2 infection in adult patients.
Private insurers will have to cover the cost of 8 at-home COVID-19 tests per person per month.
Cryotherapy applied over closed surgical incisions decreased postoperative pain and opioid consumption.
Impaired quality of life in people following hypoparathyroidism surgery and treatment is increasingly acknowledged. Researchers analyzed this with a questionnaire.
For patients with chronic osteoarthritis (OA) pain, duloxetine added to usual care has no effect compared with usual care alone.
Hormone levels in utero may be linked to the risk for developing migraine in adulthood, and risk may differ by sex.
Researchers assessed the safety and efficacy of the FLECTOR (diclofenac epolamine) topical system in children.
In a case-control study, researchers assessed risk factors for persistent neuropathic pain in those who have recovered from COVID-19 and observed their serum level of neurofilament light chain.
Scottish researchers tested the accuracy of the QCovid algorithm, a risk prediction tool developed in the UK for predicting adverse COVID-19 outcomes.
The approval was based on data from the 2-year phase 3 JUNIPERA study that evaluated secukinumab in pediatric patients aged 2 to 17 years with a confirmed diagnosis of ERA or JPsA.
The use of hyaluronic acid (HA) injections for knee osteoarthritis in Medicare beneficiaries increased substantially from 2012 to 2018.
Opioids were prescribed at a higher level by practitioners during the period of the COVID-19 pandemic examined.
SARS-CoV-2 infection shares similar morphological alterations with dry eye disease and diabetic corneas, researchers say.
Cardiac surgery patients can manage postoperative pain with nonopioid pain medications at home.
During the last decade, there has been a decline in total opioid morphine milligram equivalents (MME) per capita.
Researchers investigated the cause of dyspnea in individuals with long-haul COVID and also screened the patients for myalgic encephalomyelitis/chronic fatigue syndrome.
Read writer Diane Eastabrook’s compelling series of articles describing how loneliness and isolation are affecting seniors living at home.
Subclinical synovitis frequently precedes the development of inflammatory arthritis among anti-cyclic citrullinated peptide (CCP) 2-positive at-risk individuals with musculoskeletal symptoms but without clinical synovitis (CCP2+ at-risk).
High-dose spinal cord stimulation was efficacious for the treatment of painful diabetic neuropathy.
Researchers sought to examine the relationship between depressive symptoms and pain in U.S. veterans 50 years of age or older.
There was a decrease in nonpharmacologic therapy and an increase in opioid prescription during the COVID-19 pandemic versus 2019.
National health care spending in 2020 increased 9.7% in the United States.
Study data published in Neuropsychiatric Disease and Treatment outline the primary factors affecting attrition in buprenorphine treatment for opioid use disorder.
Pain-related threat and safety learning are altered in the setting of chronic back pain.
XT-150 is a locally injectable nonviral therapy expressing interleukin (IL)-10v, a proprietary modified variant of IL-10.
Researchers sought to provide an overview of pain conditions in children with cerebral palsy using the International Classification of Diseases, 11th Revision.
The efficacy of a small molecule that inhibits the glycine transporter type 2 and the serotonin receptor 5-hydroxytryptamine 2A was investigated for postoperative pain after colorectal surgery.
Acute opioid consumption after cesarean delivery was not reduced with the inclusion of gabapentin in a multimodal analgesic regimen among chronic buprenorphine users.
Therapeutic exposure to opioids in the pediatric care setting likely increases risk for nonmedical opioid use later in life.
A decrease in the number of excess postoperative opioid medications resulted from the implementation of a mandatory prescription drug monitoring program.
This study found no evidence that stronger opioids were superior to milder opioids for subacute pain.
Individuals with low back pain responded to educational messaging about self-management differently on the basis of pain intensity.
About 12% of patients who filled an opioid prescription within 14 days of cardiac implantable electronic device procedures have persistent opioid use.
Medical information is especially valuable to data thieves for a number of reasons.
Paxlovid consists of PF-07321332, which inhibits the viral replication of SARS-CoV-2 by blocking the activity of the SARS-CoV-2-3CL protease, and low-dose ritonavir.
Video teleconferencing (VTC) is an effective alternative to in-person health care services for many common conditions.
The goal of the study was to assess whether certain aspects of pain intensity other than ‘average’ pain could be perceived as useful to healthcare providers.
Twenty sessions of acupuncture over an 8 week period improved symptoms of severe chronic prostatitis/chronic pelvic syndrome.
The designation is supported by data from the phase 3 C.L.E.A.R. trial.
The American Society of Regional Anesthesia and Pain Medicine and the American Academy of Pain Medicine charged a multinational, multispecialty panel of experts to develop conservative guidelines for the diagnosis and treatment of neck pain.
Abortion providers in Texas can sue state officials in federal court over the state’s new abortion law, the U.S. Supreme Court ruled, but it refused to block the law while such legal actions may be taken.
Unintentional opioid deaths from July 2017 to June 2020, the pre and post Covid-19 era, are described by key decedent and death scene characteristics.
In addition to instituting flexible work schedules to attract and retain employees, practices can consider technologic solutions that reduce staffing needs by improving office efficiency.
Current published research supporting the use of intradiscal mesenchymal stem cells and PRP for discogenic back pain is of low quality.
Zavegepant is an investigational calcitonin gene-related peptide (CGRP) receptor antagonist.
Regulora is designed to provide seven 30-minute sessions of remote behavioral therapy based on gut-directed hypnotherapy.
In a systematic literature review, researchers sought to identify, summarize, and compare data on nonpharmacologic interventions for pain management among patients with dementia and assess their effectiveness.
Researchers sought to explore how inpatients understand and utilize the Verbal Rating Scale in a hospital setting.
Researchers conducted a study that compared the effectiveness of antigen-based rapid diagnostic testing vs reverse transcription quantitative polymerase chain reaction testing in ruling out SARS-CoV-2 infection in symptomatic patients.
Researchers compared opioid-sparing effects between intravenous acetaminophen and oral acetaminophen in pediatric patients undergoing tonsillectomy and adenoidectomy.
Platelet-rich plasma injections did not significantly improve knee osteoarthritis pain symptoms or joint structure compared with placebo injections in a randomized controlled trial.
Investigators conducted a scoping review to determine outcomes among patients with opioid-use disorder who received treatment with methadone in an office-based setting.
Preoperative neuropathic pain may be associated with the development of persistent postoperative pain after arthroplasty.
Fifteen treatments with active tDCS were superior to sham tDCS only with regards to depression and anxiety in fibromyalgia.
In a meta-analysis, study authors assessed the effectiveness and safety of nonsteroidal anti-inflammatory drugs and opioids for knee and hip osteoarthritis pain and physical function.
A team of investigators sought to determine whether clinically meaningful improvement in pain can affect outcomes in patients with psoriatic arthritis.
The researchers examined data from the National Health and Nutrition Examination Survey.
Physical therapy prior to and after total knee replacement may reduce long-term opioid use after surgery
Investigators conducted a systematic review and meta-analysis to examine the impact of financial incentives on outcomes among patients having undergone treatment for opioid use disorder.
This population-based cohort study found an association between new tramadol prescription and increased risk for mortality, cardiovascular events, and fractures.
A team of investigators conducted a cross-sectional study to explore the association between an increased pain threshold and risk of self-harm in youth.
Psychological interventions provided after surgery affected pain outcomes.
Seven common guiding principles were formulated for the management of acute perioperative pain.
Researchers aimed to identify predictors for acute postsurgical pain and pain at 3 months after surgery to develop prediction models.
In a systematic review and meta-analysis, researchers sought to compare outcomes associated with the use of lasmiditan, rimegepant, and ubrogepant vs triptans for the acute management of migraine headaches.
A new model could help surgeons predict the probability of pain reduction following cholecystectomy and inform decisions regarding which patients with uncomplicated cholelithiasis could benefit from surgery.
Study authors conducted a systematic review and meta-analysis to determine the effect of different exercise treatments on pain intensity in adults with chronic low back pain.
The authorization was based on data from a randomized, double-blind study that evaluated the efficacy and safety of EaseVRx in 179 patients with chronic lower back pain.
Investigators assessed the effect of pain reprocessing therapy among patients with chronic low back pain.
Celecoxib may be safe and effective for the treatment of acute migraine and migraine-associated symptoms among patients with episodic migraine.
The HER-MES trial included 777 adults with episodic or chronic migraine (at least 4 migraine days/month) who were treatment-naïve, not suitable for, or had previously failed up to 3 prophylactic migraine treatments.
Buprenorphine misuse was trending downward between 2015 and 2019 among American adults with an opioid use disorder.
The investigational intranasal formulation of nalmefene demonstrated a more rapid onset and longer duration of action compared with naloxone.
No one depression intervention type has demonstrated its superiority in populations of patients living with differing types of pain.
Effects of a law implemented to limit prescriptions for Schedule II opioids in Florida on patients receiving chronic opioid therapy were assessed.
A high prevalence of depression and anxiety symptoms was found among patients with diabetic polyneuropathy.
In an open-label, randomized, noninferiority trial, researchers compared patient-reported outcomes, defined as secondary objectives in the ELEVATE trial, after a single treatment with high-concentration capsaicin cutaneous patch to daily oral pregabalin for 8 weeks.
There is evidence of a trend signaling that men with sickle cell disease may be more likely than women be prescribed an opioid in the emergency department.