Featured Pain Articles, News | Latest Case Studies & Features



off label button

Off-Label Use of Antidepressants for Chronic Pain

In recent years, the off-label prescription of antidepressants for the treatment of chronic pain has increased, along with evidence of their effectiveness and mechanistic underpinnings when used for this purpose. Depression is a common comorbidity among patients with chronic pain, and the use of these agents may alleviate symptoms of both disorders. Typically, however, significantly…
vagus nerve stimulation

Reviewing Noninvasive Vagus Nerve Stimulation for Migraine, Cluster Headache

A substantial percentage of patients with primary headache disorders are unresponsive to standard pharmacologic therapies, with pain-free response rates of 45% at 15 minutes and 30% at 2 hours, following the use of rescue medications.1 Such findings, along with the range of side effects associated with these agents, highlight the need for novel treatment options…
Next post in Chronic Pain