Differential Diagnosis

DIC

Thrombosis: can be venous with pulmonary embolism (PE) and/or deep vein thrombosis (DVT) or arterial, as caused by peripheral artery thrombosis, myocardial infarction, and stroke


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Pulmonary Embolism

Infections

Complications of pregnancy

Malignancy

Trauma

Burns

Suggested Additional Lab Testing

D-dimer levels over the course of hours to days to determine if D-dimer levels are increasing or decreasing are suggested.

Consider imaging and vascular studies for diagnosis of DVT and PE when a D-dimer test is positive in a patient with predisposing factors for venous thrombosis.