Headache

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

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The frequency, intensity, and daily interference of headaches change over a 6-month period, with day-to-day variation being more volatile in migraine than in non-migraine headaches.

CGRP Antagonist Shows Effectiveness in Acute Migraine

CGRP Antagonist Shows Effectiveness in Acute Migraine

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Allergan has announced positive Phase 3 trial results for ubrogepant, a novel calcitonin gene-related peptide receptor antagonist for the acute treatment of migraine.

Episodic Migraine-Related White Matter Hyperintensities Ipsilateral to Pain

Episodic Migraine-Related White Matter Hyperintensities Ipsilateral to Pain

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Pain experienced by patients during episodic migraine is associated with the occurrence of white matter hyperintensities in the cerebral hemisphere ipsilateral to the pain side.

Chronic Migraine Linked to Insulin Resistance in Women

Chronic Migraine Linked to Insulin Resistance in Women

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A recent study assessed the relationship of fasting neuropeptide Y with insulin resistance, β-cell function, and glucagon-like peptide-1 secretion in patients with migraine.

Managing Headache During Pregnancy: Expert Insight

Managing Headache During Pregnancy: Expert Insight

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Headache screening should be a routine part of a prenatal visit so that if and when a patient presents with an attack, a suitable plan of action is already established.

Migraine, Tension-Type Headaches Likely in Adolescents Exposed to Violence

Migraine, Tension-Type Headaches Likely in Adolescents Exposed to Violence

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Adolescents exposed to violence or terror attacks have an increased risk for daily and weekly migraine and tension-type headache following the event.

Migraine and Multiple Sclerosis: What Is the Link?

Migraine and Multiple Sclerosis: What Is the Link?

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Increasing evidence suggests a relationship between migraine and multiple sclerosis that is beyond comorbidity and may help clarify the pathophysiology of both disorders.

Posttraumatic Stress Disorder May Predict Headache-Related Disability After Traumatic Physical Injury

Posttraumatic Stress Disorder May Predict Headache-Related Disability After Traumatic Physical Injury

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Investigators assessed single-incident traumatic physical injury survivors for symptoms of post-traumatic stress disorder and a composite of depression and anxiety symptoms.

Occipital Nerve Block, an Effective Option for Pediatric Headache

Occipital Nerve Block, an Effective Option for Pediatric Headache

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Peripheral nerve blocks for pediatric headache treatment are associated with significant benefit and minimal risk.

Subarachnoid Hemorrhage Linked to Key Clinical Characteristics of Headache

Subarachnoid Hemorrhage Linked to Key Clinical Characteristics of Headache

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Having meningismus as well as a stabbing, occiput-located headache reaching peak pain intensity in <1 second are key clinical characteristics associated with subarachnoid hemorrhage.

Prochlorperazine More Effective Than Ketamine for Treating Headaches in the Emergency Department

Prochlorperazine More Effective Than Ketamine for Treating Headaches in the Emergency Department

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Investigators found that patients receiving prochlorperazine had a greater reduction in headache-related pain compared with patients receiving ketamine.

Migraine Frequency Reduced With Erenumab, Fremanezumab

Migraine Frequency Reduced With Erenumab, Fremanezumab

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Complete results from 2 phase 3 trials examining the effects of 2 humanized monoclonal antibodies in patients with episodic and chronic migraine were published simultaneously.

Patients With Migraine Frequently Revisit the Emergency Department for Headache

Patients With Migraine Frequently Revisit the Emergency Department for Headache

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More than 25% of patients presenting to the emergency department (ED) for migraine typically require subsequent ED revisits for headache within a 6-month period.

Higher Migraine Frequency Increases Severity of Depression, Anxiety

Higher Migraine Frequency Increases Severity of Depression, Anxiety

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Frequent migraines with or without aura were shown to increase the severity of anxiety and depression.

Chronic Pain Associated With Traumatic Brain Injury: Causes and Management

Chronic Pain Associated With Traumatic Brain Injury: Causes and Management

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Although more than three-quarters of TBI cases are mild with rapid symptom resolution, some people suffer persistent debilitation and pain.

New Daily Persistent Headache Associated With Sleep Disturbances in Children

New Daily Persistent Headache Associated With Sleep Disturbances in Children

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Pediatric patients with new daily persistent-headache experience more sleep disturbances than patients with migraine or tension-type headaches.

Newly Defined Chronic Daily Headache Subtype Associated With Elevated CSF Pressure

Newly Defined Chronic Daily Headache Subtype Associated With Elevated CSF Pressure

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A recently published case series describes a new subtype of chronic daily headache that appears to be associated with elevated cerebrospinal fluid (CSF) pressure.

HIV-Positive Patients Experience Frequent Headaches

HIV-Positive Patients Experience Frequent Headaches

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A large proportion of HIV-positive patients experience frequent headaches that often impact their quality of life.

Clinician Predictors of Low-Value Imaging to Guide Intervention Targets

Clinician Predictors of Low-Value Imaging to Guide Intervention Targets

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Several strong clinician predictors of low-value imaging, such as ordering low-value imaging on a prior patient, high rates of low-value imaging in another clinical scenario, and ownership of imaging equipment, can help guide intervention targets to improve the value of care for patients.

Using Stress to Predict Risk of Migraine Even Before Predromal Symptoms

Using Stress to Predict Risk of Migraine Even Before Predromal Symptoms

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Among individuals diagnosed with episodic migraines, stressful events can accurately predict an individual's risk of a headache, even before the onset of prodromal symptoms.

Correlation Between Headache and CSF in Idiopathic Intracranial Hypertension

Correlation Between Headache and CSF in Idiopathic Intracranial Hypertension

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Findings from a recent study were unable to show a cause and effect relationship between headache and cerebrospinal fluid pressure in idiopathic intracranial hypertension, despite that headache is typically the first symptom.

PTSD More Likely in Pregnant Women With Migraines

PTSD More Likely in Pregnant Women With Migraines

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Women who are pregnant and have migraines are more likely to have posttraumatic stress disorder (PTSD) than women without migraine.

Lasmiditan Effective in Phase 3 Trial for Acute Migraine

Lasmiditan Effective in Phase 3 Trial for Acute Migraine

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Eli Lily announced positive results from a Phase 3 trial of their first-in-class drug lasmiditan for the acute treatment of migraine.

Complementary and Integrative Medicine in Migraine and Headache Management

Complementary and Integrative Medicine in Migraine and Headache Management

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Several methods of complementary and integrative medicine bring value and their integration into a headache management plan in the clinical setting empowers patients' healing process.

Onabotulinumtoxin A for Migraine: High Satisfaction, Compliance

Onabotulinumtoxin A for Migraine: High Satisfaction, Compliance

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Most centers follow recommended guidelines for the use of onabotulinumtoxin A in chronic migraine and applied a consistent measure of response to therapy of a 30% to 50% reduction in headache days.

Minimum Headache Duration Requiring Subarachnoid Hemorrhage Evaluation

Minimum Headache Duration Requiring Subarachnoid Hemorrhage Evaluation

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Patients with acute onset of severe headache should undergo diagnostic testing for subarachnoid hemorrhage, a potentially dangerous cause of headache, if the minimum duration of headache is present.

Preemptive Analgesia With Acetaminophen Reduces Headaches Associated With Electroconvulsive Therapy

Preemptive Analgesia With Acetaminophen Reduces Headaches Associated With Electroconvulsive Therapy

A significant reduction in the incidence and severity of headaches associated with electroconvulsive therapy (ECT) was observed in patients receiving preemptive analgesia with acetaminophen.

Finding the Link Between Migraine and Cerebral Blood Flow

Finding the Link Between Migraine and Cerebral Blood Flow

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Overall blood flow velocity remains unchanged during migraine headache, although blood flow velocity may be decreased early on in the attack.

Complementary and Alternative Medicine Use low for Migraine Treatment

Complementary and Alternative Medicine Use low for Migraine Treatment

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While some CAM products have shown beneficial effects for migraine treatment, previous studies have not explored reasons for using CAM and the types of CAM used.

New Device for Treating Cluster Headaches Available

New Device for Treating Cluster Headaches Available

gammaCore, a hand-held device for treating episodic cluster headaches via mild electrical stimulation of the vagus nerve is now available in the United States.

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