Headache
Rapid Treatment Onset, Reduced Headache Days With Galcanezumab
July 09, 2018In the post-hoc analysis, researchers evaluated the time to onset of effect of galcanezumab as well as whether treatment with the study drug was associated with a reduction in migraine headache days.
OnabotulinumtoxinA Safer, More Effective for Headache Prevention Than Topiramate
July 03, 2018This randomized, open-label study examined participant reported outcomes, safety, and tolerability of onabotulinumtoxinA and topiramate in adults with chronic migraines.
Polypharmacy in Primary Headache Risks Chronicization and Further Complications
June 25, 2018Polypharmacy in individuals with primary headache may arise out of a prescribing cascade.
Cannabis Use High in Migraine
June 14, 2018A high percentage of cannabis users take the drug to treat headache and probable migraine.
Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache
May 21, 2018Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.
Managing Pediatric Migraine: Current Therapies and Future Directions
May 18, 2018Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.
NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term
May 17, 2018The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.
Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk
May 17, 2018Migraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events.
Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study
May 16, 2018The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.
Antidepressant Medications and Headache: Is There a Link?
May 14, 2018Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).
Avoiding Treatment Effect Overestimation in Medication-Overuse Headache
May 10, 2018A period of observation after an educational session may be important to confirm medication-overuse headache (MOH) diagnoses.
Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity
May 10, 2018Repeated injections of nerve growth factor may lead to increased mechanical sensitivity in the masseter — but not in the temporalis muscle — as well as increased entropy.
Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study
May 03, 2018Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.
Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine
May 03, 2018Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.
Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine
May 03, 2018Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.
Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable
May 03, 2018Although high-quality studies on the use of peripheral nerve blocks for the treatment of headache disorders are scarce, results observed in clinical practice support their use.
OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine
May 03, 2018Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.
Balloon Angioplasty Provides Clinical Relief in Headache-Positive MS
May 02, 2018Percutaneous transluminal angioplasty maybe beneficial for reducing headaches in relapsing remitting and secondary progressive multiple sclerosis.
Headache in Older Adults: Unique Causes and Treatments
April 25, 2018It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.
C2 Peripheral Nerve Electroacupuncture Effectively Treats Primary Headache
April 20, 2018Peripheral nerve field stimulation with electroacupuncture may represent a less invasive mode of treating primary headache.
Medication-Overuse Headache: Risk Factors May Serve as Treatment Progress Indicators
April 12, 2018Factors that were associated with medication overuse headache in this study included high headache-related disability, attempts to escape and avoid stimuli associated with pain, and the use of combination medications.
Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'
April 12, 2018The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.
Clinical Vignette: Facial Pain, Headaches, and Neck Pain
April 02, 2018A 39-year-old woman presents with a 2-year history of facial pain, headaches, and neck pain.
Physicians Present Recommendations For and Against Acupuncture for Pain
March 27, 2018In the approach adopted by NICE, the benefit of acupuncture is compared with sham acupuncture rather than a direct comparison with pharmaceutical treatments.
Undifferentiated Headaches Common in Children, Adolescents
March 26, 2018Researchers introduce and investigate a new category of headache termed undifferentiated headache in a pediatric population.
Evaluating Headache in the Elderly: Primary vs Secondary Causes
March 23, 2018Given the unique challenges presented by aging, new cases of headache in older adults should be evaluated carefully for a differential diagnosis of primary headache and to exclude underlying causes of secondary headache.
Factors Associated With Headache Occurrence
March 14, 2018Reduced basic psychological need satisfaction, important factors for quality of life perception and encompassing autonomy, competence, and relatedness, was shown to be correlated with headache occurrence.
Bed Rest vs Fluid Supplementation for Postdural Puncture Headache
March 09, 2018Bed rest is not superior to early mobilization or fluid supplementation for reducing the incidence of postdural puncture headache.
Assessing the Value of Brain MRI in Migraine With Normal Neurologic Exam
March 06, 2018Routine brain magnetic resonance imaging is not necessary for those with migraine who have normal neurologic function unless there is a clear clinical indication that there are underlying structural abnormalities.
Targeted Group Education for Chronic Headache in Adolescents
March 01, 2018Researchers reviewed survey results to determine whether adolescents with chronic headache might benefit from either a 1-time comprehensive evaluation and management plan or standard care.
Clinical Pain Advisor Articles
- Aetna-CVS Merger Approved
- Striking a Balance Between Opioid Surveillance and Patient Privacy
- Demographic Characteristics of Pregnant Women With Opioid Use Disorder
- Effects of Mindfulness Therapy, Pharmacologic Prophylaxis on Catecholamine Levels in Migraine
- Initial Consultation for Neck Pain May Reduce Opioid Consumption, Healthcare Utilization
- Perioperative Pain Management in Patients With Opioid Use Disorder
- Seven-Item Pain Intensity Measure Reliable in Individuals With Dementia
- Managing Comorbid Opioid and Alcohol Use Disorder
- Cannabinoid-Associated Analgesia May Be Mediated Through Modulation of Affective Processes
- Reviewing the Efficacy of Invasive Procedures for Chronic Back, Knee Pain
- What Do Clinicians Do in Response to Aberrant Urine Drug Test Results?
- Photo Elicitation on Social Media Can Provide Perspective to Patients With Chronic Pain
- Patients Assume Postoperative Opioids Are Best for Pain Relief
- Educational Disabilities More Likely With Neonatal Abstinence Syndrome
- When Will Medicine Join the Women's Movement?
