Headache
New Device Available for Patients With Episodic Cluster Headache, Migraine
August 02, 2018The Sapphire has a rechargeable and reloadable fill capacity; it can be activated monthly by inputting a unique, prescription-only authorization code, delivered via a radio-frequency identification card that is mailed to the patient.
Ketamine Infusions May Be Effective for Refractory Headache
July 24, 2018For many patients with refractory headache, ketamine treatment may provide short-term analgesia with tolerable adverse events.
Headache Frequency May Predict Treatment Success in Pediatric Migraine
July 24, 2018The odds of first-line treatment success in pediatric migraine may be lower in patients who have higher baseline headache frequency and medication overuse headache.
Poll: Should Migraineurs Avoid Headache Triggers?
July 16, 2018Dr Richard Lipton and Dr Paul Martin debated the pros and cons of trigger avoidance in patients with migraine headache at the 2018 American Headache Society Annual Scientific Meeting in San Francisco, California.
Posttraumatic Headaches More Severe, Frequent Than Nontraumatic Headaches
July 10, 2018The investigators assessed participants for photophobia, unilateral location, phonophobia, exacerbation, nausea, pulsatility, sensory aura, pain level and frequency, visual aura, and allodynia features.
Rapid Treatment Onset, Reduced Headache Days With Galcanezumab
July 09, 2018In the post-hoc analysis, researchers evaluated the time to onset of effect of galcanezumab as well as whether treatment with the study drug was associated with a reduction in migraine headache days.
Headache Calendar Helps Patients Track Relationship Between Headache, Triggers
July 06, 2018This cross-sectional, observational study sought to evaluate the accuracy of individuals with headache to appraise the relationship between potential trigger factors and headache events.
Headache Calendar Helps Patients Track Relationship Between Headache, Triggers
July 06, 2018This cross-sectional, observational study sought to evaluate the accuracy of individuals with headache to appraise the relationship between potential trigger factors and headache events.
OnabotulinumtoxinA Safer, More Effective for Headache Prevention Than Topiramate
July 03, 2018This randomized, open-label study examined participant reported outcomes, safety, and tolerability of onabotulinumtoxinA and topiramate in adults with chronic migraines.
Polypharmacy in Primary Headache Risks Chronicization and Further Complications
June 25, 2018Polypharmacy in individuals with primary headache may arise out of a prescribing cascade.
Sleep Quality in Chronic Tension-Type Headaches
June 21, 2018Investigators examined baseline and 1-year variables and their association with quality of sleep in chronic tension-type headaches.
Cannabis Use High in Migraine
June 14, 2018A high percentage of cannabis users take the drug to treat headache and probable migraine.
Effect of Job Characteristics on Work Ability in Patients With Chronic Headaches
June 12, 2018Lower work ability in patients with chronic migraine may be associated with high quantitative and emotional demand.
Remission Rates and Predictors of Chronic Headache
May 24, 2018Investigators examined remission rates and predictors of remission in patients with chronic headache over 11 years.
Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache
May 21, 2018Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.
Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache
May 21, 2018Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.
Managing Pediatric Migraine: Current Therapies and Future Directions
May 18, 2018Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.
NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term
May 17, 2018The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.
NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term
May 17, 2018The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.
Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk
May 17, 2018Migraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events.
Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study
May 16, 2018The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.
Beneficial Effect of Aerobic Exercise in Migraine via Modulation of Avoidance Behavior
May 14, 2018The effect of aerobic exercise in reducing migraine-associated burden in individuals with comorbid tension-type headache and neck pain may not be mediated by an effect on nociceptive pathways.
Antidepressant Medications and Headache: Is There a Link?
May 14, 2018Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).
Avoiding Treatment Effect Overestimation in Medication-Overuse Headache
May 10, 2018A period of observation after an educational session may be important to confirm medication-overuse headache (MOH) diagnoses.
Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity
May 10, 2018Repeated injections of nerve growth factor may lead to increased mechanical sensitivity in the masseter — but not in the temporalis muscle — as well as increased entropy.
Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study
May 03, 2018Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.
Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine
May 03, 2018Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.
Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine
May 03, 2018Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.
Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable
May 03, 2018Although high-quality studies on the use of peripheral nerve blocks for the treatment of headache disorders are scarce, results observed in clinical practice support their use.
OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine
May 03, 2018Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.
Clinical Pain Advisor Articles
- Manual Therapy vs Opioids for Management of Shoulder, Spine Pain
- Intervention by Pharmacists May Effectively Reduce Use of Inappropriate Medications in the Elderly
- PainDETECT May Not Be Optimal to Detect Neuropathic Components of Orofacial Pain
- Prescription Digital Therapeutic Approved for Opioid Use Disorder
- Cannabinoids May Be Effective on Experimental Pain Threshold and Tolerance, Not Intensity
- Serum Vitamin D Levels and Risk for Migraine
- Rimegepant Orally Dissolving Formulation Provides Rapid Relief From Acute Migraine
- Updated Evidence-Based Recommendations for Buprenorphine Treatment
- Prescription Digital Therapeutic Approved for Opioid Use Disorder
- Persistence of Post-Traumatic CRPS Associated With Initial Pain Sensitization
- Kinesiophobia May Be Associated With Greater Cutaneous Allodynia in Migraine
- CDC: 8.8% of Individuals in the United States Uninsured in First Half of 2018
- Patient Experiences Shed Light on Diagnostic Errors
- Topical Migraine Trigger Point Treatment as Effective as Injection
- Wikipedia in Medical Education: An Educator's Guide to Crowdsourcing
