Headache

New Device Available for Patients With Episodic Cluster Headache, Migraine

New Device Available for Patients With Episodic Cluster Headache, Migraine

By

The Sapphire has a rechargeable and reloadable fill capacity; it can be activated monthly by inputting a unique, prescription-only authorization code, delivered via a radio-frequency identification card that is mailed to the patient.

Ketamine Infusions May Be Effective for Refractory Headache

Ketamine Infusions May Be Effective for Refractory Headache

By

For many patients with refractory headache, ketamine treatment may provide short-term analgesia with tolerable adverse events.

Headache Frequency May Predict Treatment Success in Pediatric Migraine

Headache Frequency May Predict Treatment Success in Pediatric Migraine

By

The odds of first-line treatment success in pediatric migraine may be lower in patients who have higher baseline headache frequency and medication overuse headache.

Poll: Should Migraineurs Avoid Headache Triggers?

Poll: Should Migraineurs Avoid Headache Triggers?

By

Dr Richard Lipton and Dr Paul Martin debated the pros and cons of trigger avoidance in patients with migraine headache at the 2018 American Headache Society Annual Scientific Meeting in San Francisco, California.

Posttraumatic Headaches More Severe, Frequent Than Nontraumatic Headaches

Posttraumatic Headaches More Severe, Frequent Than Nontraumatic Headaches

By

The investigators assessed participants for photophobia, unilateral location, phonophobia, exacerbation, nausea, pulsatility, sensory aura, pain level and frequency, visual aura, and allodynia features.

Rapid Treatment Onset, Reduced Headache Days With Galcanezumab

Rapid Treatment Onset, Reduced Headache Days With Galcanezumab

By

In the post-hoc analysis, researchers evaluated the time to onset of effect of galcanezumab as well as whether treatment with the study drug was associated with a reduction in migraine headache days.

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

By

This cross-sectional, observational study sought to evaluate the accuracy of individuals with headache to appraise the relationship between potential trigger factors and headache events.

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

Headache Calendar Helps Patients Track Relationship Between Headache, Triggers

By

This cross-sectional, observational study sought to evaluate the accuracy of individuals with headache to appraise the relationship between potential trigger factors and headache events.

OnabotulinumtoxinA Safer, More Effective for Headache Prevention Than Topiramate

OnabotulinumtoxinA Safer, More Effective for Headache Prevention Than Topiramate

By

This randomized, open-label study examined participant reported outcomes, safety, and tolerability of onabotulinumtoxinA and topiramate in adults with chronic migraines.

Polypharmacy in Primary Headache Risks Chronicization and Further Complications

Polypharmacy in Primary Headache Risks Chronicization and Further Complications

By

Polypharmacy in individuals with primary headache may arise out of a prescribing cascade.

Sleep Quality in Chronic Tension-Type Headaches

Sleep Quality in Chronic Tension-Type Headaches

By

Investigators examined baseline and 1-year variables and their association with quality of sleep in chronic tension-type headaches.

Cannabis Use High in Migraine

Cannabis Use High in Migraine

By

A high percentage of cannabis users take the drug to treat headache and probable migraine.

Effect of Job Characteristics on Work Ability in Patients With Chronic Headaches

Effect of Job Characteristics on Work Ability in Patients With Chronic Headaches

By

Lower work ability in patients with chronic migraine may be associated with high quantitative and emotional demand.

Remission Rates and Predictors of Chronic Headache

Remission Rates and Predictors of Chronic Headache

By

Investigators examined remission rates and predictors of remission in patients with chronic headache over 11 years.

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

By

Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

By

Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.

Managing Pediatric Migraine: Current Therapies and Future Directions

Managing Pediatric Migraine: Current Therapies and Future Directions

By

Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

By

The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

By

The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.

Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk

Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk

By

Migraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events.

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

By

The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.

Beneficial Effect of Aerobic Exercise in Migraine via Modulation of Avoidance Behavior

Beneficial Effect of Aerobic Exercise in Migraine via Modulation of Avoidance Behavior

By

The effect of aerobic exercise in reducing migraine-associated burden in individuals with comorbid tension-type headache and neck pain may not be mediated by an effect on nociceptive pathways.

Antidepressant Medications and Headache: Is There a Link?

Antidepressant Medications and Headache: Is There a Link?

By

Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).

Avoiding Treatment Effect Overestimation in Medication-Overuse Headache

Avoiding Treatment Effect Overestimation in Medication-Overuse Headache

By

A period of observation after an educational session may be important to confirm medication-overuse headache (MOH) diagnoses.

Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity

Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity

By

Repeated injections of nerve growth factor may lead to increased mechanical sensitivity in the masseter — but not in the temporalis muscle — as well as increased entropy.

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

By

Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

By

Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

By

Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.

Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable

Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable

By

Although high-quality studies on the use of peripheral nerve blocks for the treatment of headache disorders are scarce, results observed in clinical practice support their use.

OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine

OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine

By

Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.

Sign Up for Free e-Newsletters