Generic Name and Formulations:
Pentosan polysulfate sodium 100mg; caps.
Janssen Pharmaceuticals, Inc.
Indications for ELMIRON:
Bladder pain/discomfort due to interstitial cystitis.
Take with water 1 hr before or 2 hrs after meals. ≥16yrs: 100mg 3 times daily. Reevaluate at 3 and 6 months.
<16yrs: not recommended.
Bleeding or risk of bleeding (eg, surgery, aneurysm, GI ulcer, polyps). History of heparin-induced thrombocytopenia. Hepatic insufficiency. Splenic disorders. Pregnancy (Cat.B). Nursing mothers.
Caution with drugs that increase bleeding risk (eg, anticoagulants, tPA, aspirin, NSAIDs).
Alopecia, GI upset, headache, rash, abdominal pain, hepatic dysfunction, dizziness, increased prothrombin time, hemorrhage.
Clinical Pain Advisor Articles
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Predicting Pain Chronicization After Spine Surgery
- Chronic Low Back Pain Levels Vary Between Sex and Race
- FDA Approval of Medication With a Digital Monitoring System: Major Breakthrough or "Brave New World"?
- Errors in Clinical Notes Generated by Speech Recognition Are Not Uncommon
- Reducing Mortality After Overdose: Is Treatment for Opioid Use Disorder Effective?