Asthma/COPD:

Indications for XOPENEX HFA:

Bronchospasm.

Adults and Children:

<4yrs: not established. ≥4yrs: 2 inh every 4–6hrs; or 1 inh every 4hrs may suffice.

Warnings/Precautions:

Do not exceed recommended dose. Monitor for increased need; if inadequate control, reevaluate and consider adding an antiinflammatory (eg, corticosteroids). Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm, cardiovascular effects, or hypersensitivity reactions occur. Cardiovascular disorders (esp. coronary insufficiency, arrhythmias, hypertension). Seizure disorders. Diabetes. Hyperthyroidism. Hypokalemia. Renal impairment; monitor (esp. in elderly). Elderly. Labor & delivery. Pregnancy. Nursing mothers.

Pharmacologic Class:

Beta-2 agonist.

Interactions:

Avoid within 2 weeks of MAOIs, tricyclic antidepressants. Avoid other short-acting sympathomimetic aerosol bronchodilators, epinephrine. Antagonized by β-blockers. Caution with other drugs that may lower serum potassium (eg, diuretics). Monitor digoxin.

Adverse Reactions:

Accidental injury, bronchitis, dizziness, pharyngitis, rhinitis, vomiting, palpitations, chest pain, tachycardia, headache, tremor, nervousness.

Generic Availability:

Vials (YES); HFA (NO)

How Supplied:

Inhaler w. actuator (200 inh)—15g; Soln 0.31mg/3mL, 0.63mg/3mL, 1.25mg/3mL—24 vials; Concentrate 1.25mg/0.5mL—30 vials

Pricing for XOPENEX HFA

15g of 45mcg inhaler (Qty: 1)
Appx. price $40
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