Indications for TRILURON:
Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and analgesics (eg, acetaminophen).
Prior to treatment: remove joint effusion (use separate syringe), if present; and give local anesthetic (eg, lidocaine) by SC inj. Inject 2mL intra-articularly in each affected knee weekly for 3 weeks. Use separate vial/syringe for each knee.
Infection or skin disease at inj site.
Treatment cycle <3 injections: not established. Avian protein, feather, egg allergy. Avoid strenuous activity within 48hrs after injection. Pregnancy. Nursing mothers.
Avoid disinfectants with quaternary ammonium salts. Concomitant other intra-articular injectables: not recommended.
Gastrointestinal complaints, inj site pain, headache, local skin reactions, knee swelling/effusion, pruritus; transient knee inflammation.
Generic Drug Availability:
Single-use vials—1; Single-use prefilled syringes—1