Hyperacidity, GERD, and ulcers:
Indications for NEXIUM 24HR:
Frequent heartburn (≥2 days/week). Not intended for immediate relief of heartburn (may take 1–4 days for full effect).
Swallow whole. Take before eating in the AM. ≥18yrs: 20mg once daily for 14 days; may repeat 14-day course every 4 months.
<18yrs: not recommended.
Trouble or pain swallowing food. Vomiting with blood. Bloody or black stools. Chest or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck, or shoulders; or lightheadedness. Frequent chest pain.
Heartburn >3 months. Frequent wheezing. Unexplained weight loss. Nausea/vomiting. Stomach pain. Discontinue and reevaluate if condition continues or worsens after 14 days, require >1 course of treatment every 4 months; diarrhea, rash, or joint pain develops. Pregnancy. Nursing mothers.
Proton pump inhibitor.
May affect or be affected by blood-thinning agents (eg, warfarin, clopidogrel, cilostazol), antifungals, digoxin, diazepam, tacrolimus, mycophenolate mofetil, antiretrovirals, methotrexate.
Diarrhea, rash, joint pain.
Caps—14, 28, 42