• Muscle spasms

Muscle spasms:

Indications for MYOBLOC:

Cervical dystonia, to reduce severity of abnormal head position and neck pain.

Adult:

Should be administered and managed by experienced physicians. Individualize. Treatment-experienced: Initially 2500 to 5000 Units divided among affected muscles. Treatment-naïve: use lower initial dose. Adjust subsequent doses based on response.

Children:

Not recommended.

Contraindications:

Infection at proposed inj site.

Boxed Warning:

Distant spread of toxin effect.

Warnings/Precautions:

Not interchangeable with other botulinum toxin products. Spread of botulinum toxin effects my be observed beyond the local injection site. Pre-existing dysphagia. Respiratory disorders. Neuromuscular disorders (eg, myasthenia gravis, ALS, Lambert-Eaton syndrome); monitor closely. Contains human albumin; monitor for possible viral disease transmission. Pregnancy (Cat.C). Nursing mothers.

Pharmacologic Class:

Neuromuscular blocker.

Interactions:

May be potentiated by aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds). Concomitant other botulinum toxin products may potentiate neuromuscular paralysis.

Adverse Reactions:

Inj site reactions, dry mouth, dysphagia (may be severe), dyspepsia, headache; respiratory difficulties, allergic reactions (discontinue if occurs).

Generic Availability:

NO

How Supplied:

Single-use vial—1