Indications for GRIS-PEG:
Ringworm infections of the skin, scalp, and nails.
375mg daily as 1 or more divided doses; max 750mg daily.
<2 yrs: not recommended. 35-60lbs: 125–187.5mg daily. >60lbs: 187.5mg–375mg daily.
Porphyria. Hepatocellular failure. Pregnancy.
Continue therapy until infection is eradicated. Periodic monitoring of renal, hepatic, and hematopoietic functions. Discontinue if granulocytopenia occurs. Penicillin sensitivity. Avoid exposure to sunlight or UV light. Nursing mothers.
Antagonizes oral anticoagulants. Antagonized by barbiturates. May potentiate alcohol. Oral contraceptives may be less effective.
Oral thrush, GI distress, dizziness, confusion, peripheral neuritis, photosensitivity, granulocytopenia, leukopenia, proteinuria, lupus-like syndrome.
Tabs 125mg—100; 250mg—100, 500