Miscellaneous musculoskeletal disorders:
Indications for EXONDYS 51:
Duchenne muscular dystrophy (DMD) in patients with a confirmed DMD gene mutation that is amenable to exon 51 skipping.
Adults and Children:
May apply topical anesthetic cream to IV site prior to administration. Give by IV infusion over 35–60mins. 30mg/kg once weekly.
Warnings/Precautions:
Treat appropriately and consider slowing the infusion or interrupting therapy if a hypersensitivity reaction occurs. Renal impairment. Pregnancy. Nursing mothers.
Pharmacologic Class:
Antisense oligonucleotide.
Interactions:
Do not mix or infuse with other medications concomitantly via same IV access line.
Adverse Reactions:
Balance disorder, vomiting, contact dermatitis; hypersensitivity reactions.
Generic Availability:
NO
How Supplied:
Single-dose vial (2mL, 10mL)—1
Pricing for EXONDYS 51
10ml of 50mg/ml
vial
(Qty: 1)
Appx. price
$7922
