The lack of a standard definition for disease flare made recognizing them complicated, but it's now easier thanks to a new and effective identification tool from OMERACT.
Increased baseline gene expression in peripheral blood may be associated with improved clinical response to methotrexate in rheumatoid arthritis.
A sizeable percentage of patients with rheumatoid arthritis who are in clinical remission have evidence of disease activity on magnetic resonance imaging of the foot that is mostly affected.
For every 5 patients with RAs displaying improved disease activity scores or remission by clinical criteria, 2 will exhibit disease progression on MRI.
DAS28 were found to be significantly higher at baseline and at 12-month follow-up in a group of patients (n=9) with knee osteoarthritis.
"Improved pain management should be explored in patients who report high disease activity."
Much of the disability associated with RA relates to the pain secondary to inflammatory joint inflammation.
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