Chronic Pain

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Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat is a soluble guanylate cyclase stimulator currently in Phase 2 development.

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

Differing formulations and ratios of the subjects' medical cannabis regimens have been accounted for, though further information about ratios of CBD and TCH are subject to change due to continued ongoing research.

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

Pain in patients with multiple sclerosis may affect their daily functioning regardless of disease severity.

Development of Chronic Pain Highly Dependent on Pain History

Development of Chronic Pain Highly Dependent on Pain History

The development of and recovery from chronic pain was found to be highly dependent on a patient's previous history of pain.

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education combined with exercise as well as a single corticosteroid injection may be more effective than a wait-and-see approach for alleviating gluteal tendinopathy-associated pain.

Opioids in Setting of Hemodialysis Associated With Adverse Events

Opioids in Setting of Hemodialysis Associated With Adverse Events

Opioids were found to be associated with adverse events in older Medicare beneficiaries on hemodialysis.

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

Persistent pain — which is common in survivors of critical illnesses — may not be associated with opioid exposure during intensive care unit stay.

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

A newly developed Web-based platform designed to empower patients with chronic pain and provide them with self-management tools was found to improve self-efficacy and treatment satisfaction when administered in conjunction with nurse and social worker coaching.

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

Cognitive behavioral therapy-based psychological interventions may provide some benefits in older adults with chronic non-cancer pain.

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

Interbrain coupling of areas implicated in pain processing may be enhanced when romantic partners hold hands while 1 of the 2 is subjected to pain.