Chronic Pain News Archive

Screening for Hyperglycemia Prior to Steroid Injections for Chronic Pain

Screening for Hyperglycemia Prior to Steroid Injections for Chronic Pain

The majority of patients being considered for corticosteroid injections to treat chronic pain may be at high risk for untreated diabetes mellitus.

Persistence of Post-Traumatic CRPS Associated With Initial Pain Sensitization

Persistence of Post-Traumatic CRPS Associated With Initial Pain Sensitization

The level of pain sensitization in the early post-trauma period in patients with complex regional pain syndrome type 1 after distal radius fractures may be associated with the persistence of symptoms.

Ensuring Safety During Long-Term Opioid Therapy

Ensuring Safety During Long-Term Opioid Therapy

Healthcare providers at Veterans Affairs centers cite time constraints, logistic constraints, and interpersonal challenges as unique barriers to adherence with practice guidelines when treating patients on long-term opioid therapy.

Analgesic Modality Used for Trauma, Abdominal Pain in ED May Not Affect Persistent Pain

Analgesic Modality Used for Trauma, Abdominal Pain in ED May Not Affect Persistent Pain

Analgesic modality used in patients presenting to the emergency department with trauma, including abdominal pain, may not affect the presence of persistent pain at 6 months.

Empowering Exercise Professionals to Support Individuals With Chronic Pain

Empowering Exercise Professionals to Support Individuals With Chronic Pain

Exercise professionals may act as "key supporters" of individuals with chronic pain.

Parental Chronic Spinal Pain May Affect Prognosis in Adult Offspring

Parental Chronic Spinal Pain May Affect Prognosis in Adult Offspring

Individuals with chronic spinal pain, particularly those who are overweight or obese, may be less likely to recover from this condition if both their parents also have chronic spinal pain.

New Guidelines Issued for Patellofemoral Pain Management

New Guidelines Issued for Patellofemoral Pain Management

The National Athletic Trainers' Association has issued recommendations for identifying and managing patients with patellofemoral pain.

Stepped-Care Model Beneficial in Pain Management Practices in Primary Care

Stepped-Care Model Beneficial in Pain Management Practices in Primary Care

A stepped-care model of pain management implemented in primary care was successful in increasing the proportion of veteran patients reporting moderate to severe pain, as well as decreasing the use of opioids for pain management.

Central Sensitization in Greater Trochanteric Pain Syndrome

Central Sensitization in Greater Trochanteric Pain Syndrome

Patients with greater trochanteric pain syndrome may have altered conditioned pain modulation, as well as a high number of pain locations associated with negative conditioned pain modulation.

Factors Promoting Participation in Self-Management Training Program for Chronic Pain

Factors Promoting Participation in Self-Management Training Program for Chronic Pain

Factors underlying participation in the Living Better Beyond Pain, a self-management training program for patients with chronic pain, as well as benefits gained from participating in the program and associated barriers were identified.

Gendered Perceptions of Socially Acceptable Pain Relief Strategies

Gendered Perceptions of Socially Acceptable Pain Relief Strategies

Men and women may seek pain relief in both gendered and ungendered ways, depending on whether gender norms or perceptions of analgesic efficacy are thought to define social acceptability.

Benefits of a Pain and Stress Management Program for Chronic Pain

Benefits of a Pain and Stress Management Program for Chronic Pain

A "Pain and Stress Management" program for the management of chronic pain, was found to be effective in alleviating pain, diminishing stress, promoting self-management of pain, and ameliorating general well-being.

Predicting the Magnitude of Placebo Analgesia in Chronic Pain

Predicting the Magnitude of Placebo Analgesia in Chronic Pain

Specific characteristics in several brain structures and psychological features may predict the magnitude of the placebo response.

Smartphone App Helps Evaluate Catastrophizing in Chronic Pain

Smartphone App Helps Evaluate Catastrophizing in Chronic Pain

In patients with chronic pain conditions, daily pain assessments using a smartphone app indicated a positive correlation between perceived change in pain symptoms and levels of pain catastrophizing.

Screening Tool May Identify Distress in Parents of Children With Chronic Pain

Screening Tool May Identify Distress in Parents of Children With Chronic Pain

A self-report screening tool designed to identify impaired psychosocial functioning and behavioral responses in parents of children with chronic pain was found to be useful clinically.

OTC Analgesic Use High, Associated With Worse-Than-Expected Clinical Profiles

OTC Analgesic Use High, Associated With Worse-Than-Expected Clinical Profiles

The clinical profiles of patients taking over-the-counter pain medications were found to be poorer than expected, with a high prevalence of migraine headache and many reporting frequent and disabling pain for extended durations.

Predictors for Blinding Assessment Rates in Chronic Pain Trials

Predictors for Blinding Assessment Rates in Chronic Pain Trials

Patient blinding in randomized placebo-controlled trials on pharmacologic treatments for chronic pain conditions may seldom be assessed.

Differentiation of Knee Pain Phenotypes Among Older Adults

Differentiation of Knee Pain Phenotypes Among Older Adults

A population-based, cohort study was conducted to identify knee pain in a group of older adults.

Photo Elicitation on Social Media Can Provide Perspective to Patients With Chronic Pain

Photo Elicitation on Social Media Can Provide Perspective to Patients With Chronic Pain

For patients with chronic pain, photo elicitation on social networks may represent a novel way to get a better understanding of lived experiences with chronic pain.

Lower Weighting of Hand Cortical Representations in CRPS

Lower Weighting of Hand Cortical Representations in CRPS

Patients with unilateral complex regional pain syndrome may have a weaker illusory response to a novel finger illusion compared with healthy controls, indicating disrupted weighting of bilateral hand cortical representations.

Alpha and Beta Band Activity in MS-Related Chronic Pain

Alpha and Beta Band Activity in MS-Related Chronic Pain

Patients with multiple sclerosis-related chronic pain were found to have spectral abnormalities within the dynamic pain connectome regions.

Optimizing Treatment for Patients With Chronic Sciatica: Gabapentin vs Pregabalin

Optimizing Treatment for Patients With Chronic Sciatica: Gabapentin vs Pregabalin

In this prospective, cohort study, patients (N=18) were randomized to receive gabapentin 400-800mg 3 times daily then pregabalin 150-300mg twice daily or vice versa; each treatment regimen was taken for 8 weeks with a 1-week washout period in between.

Adverse Childhood Experienced Linked to Urologic Chronic Pelvic Pain Syndrome Symptoms

Adverse Childhood Experienced Linked to Urologic Chronic Pelvic Pain Syndrome Symptoms

Adverse childhood experiences such as sexual violence, physical violence, serious illness, and bereavement may be associated with urologic chronic pelvic pain syndrome symptoms.

Chronic Pain May Be a Contributing Factor to Suicide

Chronic Pain May Be a Contributing Factor to Suicide

Chronic pain may represent an important contributing factor to suicide.

Reviewing the Efficacy of Invasive Procedures for Chronic Back, Knee Pain

Reviewing the Efficacy of Invasive Procedures for Chronic Back, Knee Pain

Invasive procedures may not provide a substantial benefit over sham procedures for the management of chronic back or knee pain.

Mobile Health-Supported Trials to Assess Chronic Musculoskeletal Pain Treatments

Mobile Health-Supported Trials to Assess Chronic Musculoskeletal Pain Treatments

Single-patient multicrossover (n-of-1) trials supported by mobile health applications may not improve pain interference compared with usual care for patients with chronic musculoskeletal pain.

Opioid Analgesics Linked With Higher Rates of Unemployment in Chronic Pain

Opioid Analgesics Linked With Higher Rates of Unemployment in Chronic Pain

Patients taking opioid analgesics for chronic noncancer pain may have a risk for unemployment 3-fold higher compared with individuals not taking opioids.

Utility of Repeated Sacroiliac Joint MRI in Chronic Back Pain, Suspected axSpA

Utility of Repeated Sacroiliac Joint MRI in Chronic Back Pain, Suspected axSpA

Findings suggest that repeating MRI of the sacroiliac joints after 3 months or 1 year in patients with chronic back pain and suspected axial spondyloarthritis was not useful.

Overlapping Opioid and Benzodiazepine Prescriptions in Chronic Pain: Rates and Related Outcomes

Overlapping Opioid and Benzodiazepine Prescriptions in Chronic Pain: Rates and Related Outcomes

Concurrent use of benzodiazepines and long-term opioids was found in 25% of patients with chronic pain, and to be associated with elevated risk of falling and visiting the emergency department.

Perceived Injustice, Chronic Low Back Pain Intensity, and Ethnicity

Perceived Injustice, Chronic Low Back Pain Intensity, and Ethnicity

Perceptions of injustice may predict worse outcomes in patients with chronic low back pain.

Any Exposure to Smoking May Increase Risk for Chronic Widespread Pain

Any Exposure to Smoking May Increase Risk for Chronic Widespread Pain

Cigarette smoking at any point during adulthood may be associated with an increased risk for chronic widespread pain.

Factors Associated With Dynamic Balance in Greater Trochanteric Pain Syndrome

Factors Associated With Dynamic Balance in Greater Trochanteric Pain Syndrome

Kinesiophobia, pain, and physical function may be associated with dynamic balance in individuals with greater trochanteric pain syndrome.

Evidence of Altered Nociceptive Processing in Chronic Unilateral Heel Pain

Evidence of Altered Nociceptive Processing in Chronic Unilateral Heel Pain

Widespread pressure pain hypersensitivity at nerve trunks and musculoskeletal structures associated with long-standing unilateral plantar heel pain may result from altered central pain processing.

Reviewing the Efficacy of Intrathecal Morphine, Ziconotide for Cancer- and Noncancer Chronic Pain

Reviewing the Efficacy of Intrathecal Morphine, Ziconotide for Cancer- and Noncancer Chronic Pain

The use of morphine and ziconotide is consistently recommended as first-line intrathecal therapy in the management of cancer- and non-cancerchronic pain, respectively.

Adverse Event Reporting System Effective for Improved Control of Pharmacologic Therapy in Chronic Pain

Adverse Event Reporting System Effective for Improved Control of Pharmacologic Therapy in Chronic Pain

A pharmacovigilance data recording system of adverse events in patients with long-term opioid use for the management of chronic noncancer pain may be effective for improved control of pharmacologic pain therapy.

Ozone vs Corticosteroids May Provide Longer-Lasting Effects for Plantar Fasciitis

Ozone vs Corticosteroids May Provide Longer-Lasting Effects for Plantar Fasciitis

Ozone injection, despite slow onset, may provide longer-lasting outcomes compared with corticosteroid for the treatment of chronic plantar fasciitis.

CDC: About One in Five U.S. Adults Have Chronic Pain

CDC: About One in Five U.S. Adults Have Chronic Pain

About 20.4 percent of U.S. adults have chronic pain and 8.0 percent have high-impact chronic pain.

Social Support and Attachment Style May Affect Pain Experiences in Men With HIV

Social Support and Attachment Style May Affect Pain Experiences in Men With HIV

In men with HIV, daily social support may improve experiences of pain, and attachment style may influence the ways in which individuals leverage social support as a pain-coping mechanism.

Pain Processing May Be Altered in Women With Patellofemoral Pain

Pain Processing May Be Altered in Women With Patellofemoral Pain

Young women with patellofemoral pain may have altered pain processing compared with healthy controls.

Treating Chronic Prostatitis/Chronic Pelvic Pain as a Psychoneuromuscular Disorder Shows Benefits

Treating Chronic Prostatitis/Chronic Pelvic Pain as a Psychoneuromuscular Disorder Shows Benefits

Treating chronic prostatitis/chronic pelvic pain as a psychoneuromuscular disorder may significantly improve related symptoms.

Biopsychosocial Factors May Help With Coping in Chronic Temporomandibular Disorder

Biopsychosocial Factors May Help With Coping in Chronic Temporomandibular Disorder

Several biopsychosocial factors as well as temporomandibular disorder (TMD)-related symptoms were found to improve over time in individuals with chronic, but not newly developed TMD.

Pain Management After Spinal Cord Injury Should Be Tailored to Pain Level, Subtype

Pain Management After Spinal Cord Injury Should Be Tailored to Pain Level, Subtype

Pain management in patients with spinal cord injury should be tailored according to pain level and subtype.

Psych Screening Beneficial in Pediatric Abdominal Pain

Psych Screening Beneficial in Pediatric Abdominal Pain

Systematic screening for anxiety, disability, and pain can increase psychological referral rates among pediatric patients with abdominal pain.

Low Literacy Self-Management Program for Chronic Pain May Be Effective

Low Literacy Self-Management Program for Chronic Pain May Be Effective

A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.

Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain

Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain

Electroacupuncture may be safe and effective to reduce the use of opioid medications in patients with chronic musculoskeletal pain.

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

L-Glutamine Oral Therapy Reduces Sickle Cell-Related Pain Better Than Placebo

L-Glutamine oral treatment with or without hydroxyurea reduces pain crises better than placebo in individuals with sickle cell disease.

Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults

Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults

Weekly vigorous activity and cultural engagement may protect against the development of chronic pain in older adults.

Orilissa Approved for Moderate to Severe Pain Associated With Endometriosis

Orilissa Approved for Moderate to Severe Pain Associated With Endometriosis

The approval was based on data from 2 multinational double-blind, placebo-controlled Phase 3 trials involving 1686 premenopausal women with moderate to severe pain associated with endometriosis.

Hypoesthesia for Touch and Joint Position Linked to Chronic Pain in MS

Hypoesthesia for Touch and Joint Position Linked to Chronic Pain in MS

Investigators examined whether chronic pain and hypoesthesia are linked in patients with MS.

Symptom Severity, Sensory Sensitivity May Indicate Pain Centralization in Chronic Overlapping Pain Conditions

Symptom Severity, Sensory Sensitivity May Indicate Pain Centralization in Chronic Overlapping Pain Conditions

Two composite constructs of symptom patterns in Chronic Overlapping Pain Conditions were found to be associated with each other and the centralized pain phenotype.

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

Consensus Guidelines for the Use of Intravenous Ketamine for Chronic Pain

A panel of experts formulated consensus guidelines for physicians who use intravenous ketamine infusions to treat chronic pain.

Opioid Equianalgesic Doses

Opioid equianalgesic dosing chart used for interchanging between drug, route of administration, or both.

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

Percutaneous Electrolysis May Be Useful Adjunct for Subacromial Pain Syndrome

Percutaneous Electrolysis May Be Useful Adjunct for Subacromial Pain Syndrome

In patients with subacromial pain syndrome, ultrasound-guided percutaneous electrolysis plus standard therapy and exercise may not bring additional benefits in terms of disability and pressure sensitivity compared with therapy and exercise alone.

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat is a soluble guanylate cyclase stimulator currently in Phase 2 development.

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

Differing formulations and ratios of the subjects' medical cannabis regimens have been accounted for, though further information about ratios of CBD and TCH are subject to change due to continued ongoing research.

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

Pain in patients with multiple sclerosis may affect their daily functioning regardless of disease severity.

Development of Chronic Pain Highly Dependent on Pain History

Development of Chronic Pain Highly Dependent on Pain History

The development of and recovery from chronic pain was found to be highly dependent on a patient's previous history of pain.

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education combined with exercise as well as a single corticosteroid injection may be more effective than a wait-and-see approach for alleviating gluteal tendinopathy-associated pain.

Opioids in Setting of Hemodialysis Associated With Adverse Events

Opioids in Setting of Hemodialysis Associated With Adverse Events

Opioids were found to be associated with adverse events in older Medicare beneficiaries on hemodialysis.

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

Persistent pain — which is common in survivors of critical illnesses — may not be associated with opioid exposure during intensive care unit stay.

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

A newly developed Web-based platform designed to empower patients with chronic pain and provide them with self-management tools was found to improve self-efficacy and treatment satisfaction when administered in conjunction with nurse and social worker coaching.

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

Cognitive behavioral therapy-based psychological interventions may provide some benefits in older adults with chronic non-cancer pain.

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

Interbrain coupling of areas implicated in pain processing may be enhanced when romantic partners hold hands while 1 of the 2 is subjected to pain.

Novel Transcranial Magnetic Stimulation Protocol May Be Effective in CRPS

Novel Transcranial Magnetic Stimulation Protocol May Be Effective in CRPS

The use of a novel frequency pairing for transcranial magnetic stimulation may effectively relieve upper and lower extremity pain associated with complex regional pain syndrome.

Predicting Suicidal Ideation in Veterans With Chronic Pain

Predicting Suicidal Ideation in Veterans With Chronic Pain

A number of factors including chronic pain co-occurring with posttraumatic stress disorder and pain interference may predict suicidal ideation and violent impulses in US veterans with chronic pain.

Elder Abuse Not Associated With Risk for Chronic Pain

Elder Abuse Not Associated With Risk for Chronic Pain

Researchers assessed the cross-sectional and longitudinal relationships between elder abuse and neglect and chronic pain.

Assessing Outcomes of Acceptance and Commitment Therapy for Chronic Pain

Assessing Outcomes of Acceptance and Commitment Therapy for Chronic Pain

Neuropsychological performance may not be associated with the improvements in pain interference observed after an 8-week Acceptance and Commitment Therapy program in veterans with chronic pain.

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

Zohydro ER is also available in 10mg, 15mg, 30mg, 40mg, and 50mg dosage strengths.

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.

Literacy-Adapted Group CBT for Chronic Pain

Literacy-Adapted Group CBT for Chronic Pain

For patients with chronic pain, literacy-adapted group cognitive behavioral therapy and group pain education improve pain and physical function compared with usual care.

Web-Based CBT Adjunct May Address Aberrant Drug-Related Behaviors in Chronic Pain

Web-Based CBT Adjunct May Address Aberrant Drug-Related Behaviors in Chronic Pain

A web-based cognitive behavior therapy program may be associated with greater reductions in aberrant drug-related behavior, pain interference, and pain catastrophizing in patients with chronic pain treated with opioids who undergo treatment as usual compared with patients who undergo treatment as usual only.

Sleep Quality, PTSD Symptoms, and Chronic Pain in Youth

Sleep Quality, PTSD Symptoms, and Chronic Pain in Youth

For youth with chronic pain, researchers found that sleep quality partially mediated the relationships between PTSD and pain intensity and interference.

Narcotic Analgesic Formulations

Comparative chart of narcotic analgesics including formulations, strengths, and dosing intervals.

Multidisciplinary Social Cognitive Intervention May Improve Quality of Life and Autonomy for Patients With Chronic Pain

Multidisciplinary Social Cognitive Intervention May Improve Quality of Life and Autonomy for Patients With Chronic Pain

An intensive social cognitive intervention delivered by a multidisciplinary team may lead to improvements in health-related quality of life, depressive symptoms, and autonomy in patients with chronic pain.

Race/Ethnicity May Not Accurately Predict Health-Related Quality of Life in Chronic Pain

Race/Ethnicity May Not Accurately Predict Health-Related Quality of Life in Chronic Pain

Age, anxiety, and socioeconomic status are better predictors than race and ethnicity for health-related quality of life outcomes in patients with chronic pain.

Ketamine May Represent an Effective Treatment for the Management of Chronic Noncancer Pain

Ketamine May Represent an Effective Treatment for the Management of Chronic Noncancer Pain

Current evidence suggests ketamine may be an effective therapy for the management of chronic noncancer pain.

Standardized Definition of Myofascial Pain Needed to Better Treat Patients

Standardized Definition of Myofascial Pain Needed to Better Treat Patients

Health care practitioner groups differ regarding the signs and symptoms that define myofascial pain syndrome, and there is poor agreement among chiropractors, physicians, and massage therapists.

Chronic Back, Neck Pain Linked to Prior Mental Disorders

Chronic Back, Neck Pain Linked to Prior Mental Disorders

Mental disorders are positively associated with subsequent self-reported chronic back and/or neck pain, with a clear dose-response relationship between the number of mental disorders and subsequent pain.

Brain Plasticity in Patients With Complex Regional Pain Syndrome

Brain Plasticity in Patients With Complex Regional Pain Syndrome

Patients diagnosed with complex regional pain syndrome (CRPS) demonstrate significant structural and functional brain changes in regions associated with movement and pain.

Symproic Now Available for Opioid-Induced Constipation in Patients With Chronic Non-Cancer Pain

Symproic Now Available for Opioid-Induced Constipation in Patients With Chronic Non-Cancer Pain

Symproic tablets for the treatment of opioid-induced constipation in adults with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent opioid dosage escalation.

Sleep and the Relationship Between Pediatric Pain and Traumatic Stress

Sleep and the Relationship Between Pediatric Pain and Traumatic Stress

Poor sleep quality partially mediates relationships between post-traumatic stress syndrome and severity of chronic pain in pediatric patients.

Prolonged-Release Oxycodone/Naloxone Efficacious on Chronic Pain and Opioid-Induced Constipation

Prolonged-Release Oxycodone/Naloxone Efficacious on Chronic Pain and Opioid-Induced Constipation

The use of oxycodone/naloxone prolonged-release tablets (OXN PR) can provide significant relief for patients who suffer from moderate to severe chronic pain and opioid-induced constipation.

Hypertension in Chronic Pain: Risk Factors

Hypertension in Chronic Pain: Risk Factors

In patients with chronic pain, comorbid hypertension may be mediated by reduced heart rate variability and spontaneous baroreflex sensitivity.

Analgesia Maintained With Naloxegol Treatment of Opioid-Induced Constipation

Analgesia Maintained With Naloxegol Treatment of Opioid-Induced Constipation

Naloxegol was shown to maintain adequate opioid analgesia over a 12-week treatment course, while relieving opioid-induced constipation.

New Spinal Cord Stimulation Neurostimulator Available for Chronic Pain

New Spinal Cord Stimulation Neurostimulator Available for Chronic Pain

The Intelis platform monitors patient activity 24/7, which means physicians can make treatment adjustments as needed.

New Opioid Analgesic NKTR-181 Safe, Efficacious for Low Back Pain

New Opioid Analgesic NKTR-181 Safe, Efficacious for Low Back Pain

NKTR-181 was found to be safe and effective in patients with low back pain.

Patients With Chronic Pain Are Twice as Likely to Attempt Suicide

Patients With Chronic Pain Are Twice as Likely to Attempt Suicide

Sleep-onset insomnia, pain intensity, and daytime dysfunction contribute to risk of suicide in patients diagnosed with chronic pain.

Chronic Pain Management in Patients With HIV: New Guidelines

Chronic Pain Management in Patients With HIV: New Guidelines

The HIV Medicine Association of the Infectious Disease Society of America recommends that people living with HIV be screened for pain and offered both nonpharmacologic and pharmacologic treatment options.

Intrathecal Bolus Drug Delivery Safe for Breakthrough Pain

Intrathecal Bolus Drug Delivery Safe for Breakthrough Pain

Drug delivery with an intrathecal bolus is safe for the treatment and management of unpredictable breakthrough pain.

Antidepressants for Chronic Pediatric Pain?

Antidepressants for Chronic Pediatric Pain?

No conclusive evidence was found supporting the efficacy of antidepressants in the pediatric population.

Doxepin Effective for Sleep Disturbances in Patients With Chronic Pain

Doxepin Effective for Sleep Disturbances in Patients With Chronic Pain

Doxepin was not only found to be effective at improving sleep outcomes, but also generally well tolerated in patients with diverse demographic and baseline characteristics.

Intravenous Lidocaine Safe, Effective for Chronic Pain

Intravenous Lidocaine Safe, Effective for Chronic Pain

Lidocaine infusions were shown to provide long-lasting and adequate analgesia in 41% of patients with chronic pain.

Childhood Adversity Common in Patients With Fibromyalgia, Chronic Widespread Pain

Childhood Adversity Common in Patients With Fibromyalgia, Chronic Widespread Pain

Women with fibromyalgia and chronic widespread pain had elevated levels of childhood adversity, including sexual and emotional abuse.

Intrathecal Ziconotide Long-Term Efficacy and Safety for Severe Chronic Pain

Intrathecal Ziconotide Long-Term Efficacy and Safety for Severe Chronic Pain

In patients with severe chronic pain refractory to conventional therapy, intrathecal ziconotide provided long-term pain relief, particularly when used as first-line intrathecal therapy.

Chronic Disease Risk Increased With Adulthood Weight Gain

Chronic Disease Risk Increased With Adulthood Weight Gain

Weight gain during early to middle adulthood is associated with an increased risk of major chronic diseases and decreases the likelihood of healthy aging.

Morphine Microdose Therapy Safe, Effective in Chronic Non-Cancer Pain

Morphine Microdose Therapy Safe, Effective in Chronic Non-Cancer Pain

The low dose of the microdose method reduces the formation of catheter tip granuloma.

First-in-Class Chronic Pain Drug Candidate Fast Tracked

First-in-Class Chronic Pain Drug Candidate Fast Tracked

Tanezumab is a NGF inhibitor and is a first-in-class agent to receive Fast Track approval.

Abuse-Deterrent Extended-Release Morphine Sulfate Launched for Chronic Pain

Abuse-Deterrent Extended-Release Morphine Sulfate Launched for Chronic Pain

Egalet announced the launch of Arymo ER extended-release tablets for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment.

Opioids for Chronic Pain: New VA/DoD Clinical Guideline

Opioids for Chronic Pain: New VA/DoD Clinical Guideline

A new clinical practice guideline regarding the use of opioids for chronic pain has been released by the VA and DoD.

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