The use of onabotulinumtoxinA every 12 weeks over a 2-year period was found to be safe, and effective for headache prevention in patients with chronic migraine.
High levels of stress may be associated with poor acute treatment outcomes in patients with chronic migraine.
OnabotulinumtoxinA was shown to have a better outcome in patients with chronic migraine who start the treatment within 12 months of symptom onset.
An association was established between excessive daytime sleepiness and a high frequency of headaches.
Patients with chronic migraine share features with individuals with temporomandibular disorders that include kinesiophobia and neck disability.
In patients with chronic migraine and medication overuse, patients who frequently relapse into overuse following withdrawal have a worse clinical and psychological profile than patients who relapse less frequently.
Transcutaneous supraorbital neurostimulation provides an effective prophylactic treatment for patients with chronic migraine.
Examination of hypothalamic activity shows distinctly different patterns between episodic and chronic forms of migraine.
A combination of treatment with CBT and the tricyclic antidepressant amitriptyline led to greater improvements in youth with chronic migraine compared with treatment with headache education and amitriptyline.
Non-medication approaches such as biofeedback and cognitive behavioral therapy may be helpful adjunct therapies and may help with more long-term coping strategies.
Sixty and 35 percent of patients achieved a 30 and 50% reduction, respectively, in headache days and/or pain intensity.
Participants experienced a reduction in headache days as soon as 3 days post-treatment.
Cryoanalgesia for chronic headaches: easy to use, reversible
Effectiveness of an Anti-CGRP Antibody in Enhancing Wellness During Migraines' Prodrome and Postdrome PhasesJune 10, 2016
Anti-CGRP Antibody for Migraine
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