Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.
A total of 1,327 migraine patients were treated in the study for a single migraine attack. At 2 hours after migraine attack, 19.2% (n=423) and 21.2% (n=448) of ubrogepant 50mg and 100mg were pain free, respectively.
A recent study evaluated the safety and efficacy of erenumab in patients with episodic migraine who had experienced 2 to 4 previous preventive treatment failures, due to lack of efficacy or intolerable side effects.
Allergan has announced positive Phase 3 trial results for ubrogepant, a novel calcitonin gene-related peptide receptor antagonist for the acute treatment of migraine.
The monoclonal antibody erenumab has shown favorable results regarding efficacy and safety for the prevention of migraine.
In a phase 3 trial, treatment with erenumab reduced migraine frequency, monthly migraine days, and migraine medication use in patients with episodic migraine.
Migraineurs process nitrate- and nitrite-containing foods differently than the general population.
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