Misuse of opioid drugs may affect the outcomes of treatment for alcohol use disorder, and cannabis use may predict the odds of heavy drinking at the end of treatment.
Differing formulations and ratios of the subjects' medical cannabis regimens have been accounted for, though further information about ratios of CBD and TCH are subject to change due to continued ongoing research.
Researchers proposed that future projects investigate the geographical and temporal trends in substance use and its disease burden.
Reviewing the Efficacy, Safety, and Tolerability of Cannabis-Based Medicines for Chronic Neuropathic PainApril 18, 2018
The effectiveness of cannabis-based products for chronic neuropathic pain is not supported by high-quality evidence.
A national sample of about 2,000 adults aged 50 to 80 years were asked about marijuana use for medical purposes, including its perceived benefits.
Various strategies to reduce opioid overdose deaths have been implemented and it has been suggested that access to medical cannabis may lead to a reduction in opioid use for pain management.
The benefits associated with medical cannabis therapy may be overestimated due to inadequate blinding in clinical trials.
Frequent cannabis users enrolled in a Medication-Assisted Treatment for opioid addiction exhibit greater associations between pain and negative affects compared with less-frequent users.
Among cannabidiol products sold online, there is a wide range of CBD concentrations, and many products are under- or overlabeled.
Cannabis use was associated with aberrant drug behaviors in patients referred to a medication management program.
There is currently little conclusive evidence to suggest a benefit of cannabis use for the management of neuropathic pain.
Medical marijuana laws may be connected to increased rates of illicit cannabis use and cannabis use disorder, leading some users to experience negative consequences, such as motor vehicle accidents.
Interventions targeted at improving medication adherence might mitigate the adverse effects of cannabis use on psychosis outcomes.
Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.
Medical marijuana, as a botanical and a scheduled drug does not fit the FDA paradigm for drug approval, a major impediment to its use in research.
Cannabis use disorder is also rising faster in states with legalization laws
A study indicates a likely causal relationship between cannabis use and increased risk for schizophrenia.
In a study of outpatients with depression, researchers found that marijuana use was common and associated with poor recovery.
Most patients (85%) who discontinued long-term opioid use did so because of a clinician's, rather than a patient decision.
In January 2017, the National Academies of Sciences, Engineering, and Medicine released a report titled "The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendation for Research."
Recent studies show that THC consumption affects the dopamine system.
"The utility of the crystal structure may provide inspiration for drug design toward refining efficacy and avoiding adverse events."
These data implicate the cannabinoid system in decision-making regarding the allocation of cognitive effort
Researchers find male users report greater benefits compared to women
New guideline addresses cancer-related chronic pain
Advising patients on strains, explaining limitations
Vaporized cannabis had a significant analgesic response over placebo.
Pot-related poison control calls and hospital discharges spike with wider availability.
Clinical Pain Advisor Articles
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- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Virtual Reality May Effectively Reduce Sensory, Affective, and Cognitive Pain During Labor
- Electroacupuncture May Help Reduce Opioid Use in Chronic Musculoskeletal Pain
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Predicting Pain Chronicization After Spine Surgery
- Chronic Low Back Pain Levels Vary Between Sex and Race
- FDA Approval of Medication With a Digital Monitoring System: Major Breakthrough or "Brave New World"?
- Errors in Clinical Notes Generated by Speech Recognition Are Not Uncommon
- Reducing Mortality After Overdose: Is Treatment for Opioid Use Disorder Effective?