Cannabinoids

Cannabinoids May Be Effective on Experimental Pain Threshold and Tolerance, Not Intensity

Cannabinoids May Be Effective on Experimental Pain Threshold and Tolerance, Not Intensity

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Although cannabinoids were found to improve the pain experience in individuals subjected to experimental pain, they were not found to have analgesic effects on existing experimental pain, suggesting that these agents may modulate affective processes.

Endocannabinoids May Be Elevated in Women With Fibromyalgia

Endocannabinoids May Be Elevated in Women With Fibromyalgia

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Women with fibromyalgia were found to have elevated levels of endocannabinoidome lipid mediators.

Cannabis Use High in Migraine

Cannabis Use High in Migraine

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A high percentage of cannabis users take the drug to treat headache and probable migraine.

Many Oncologists Discuss, Recommend Medical Marijuana

Many Oncologists Discuss, Recommend Medical Marijuana

Many oncologists recommend medical marijuana clinically despite not feeling sufficiently knowledgeable about its utility.

Medical Marijuana Users More Likely to Use Prescription Drugs for Medical, Nonmedical Purposes

Medical Marijuana Users More Likely to Use Prescription Drugs for Medical, Nonmedical Purposes

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Patients who use medical marijuana may be more likely to use prescription drugs for both medical and nonmedical purposes.

Marijuana Legalization and Opioid Prescribing Rates

Marijuana Legalization and Opioid Prescribing Rates

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Implementing medical or adult-use marijuana laws may reduce the rate of opioid prescribing for Medicaid enrollees.

Despite Research Gap, Medical Marijuana Use Supported at End of Life in Pediatric Cancer

Despite Research Gap, Medical Marijuana Use Supported at End of Life in Pediatric Cancer

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Since the legalization of medical marijuana, clinicians must come up with appropriate responses to requests for treatment in pediatric end-of-life settings.

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

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Cotargeting of peripheral μ-opioid and cannabinoid receptors was found to have a synergistic effect in reducing mechanical allodynia in a mouse model of neuropathic pain.

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

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Various strategies to reduce opioid overdose deaths have been implemented and it has been suggested that access to medical cannabis may lead to a reduction in opioid use for pain management.

Medical Marijuana Laws, Dispensaries May Reduce Deaths From Opioid Overdose

Medical Marijuana Laws, Dispensaries May Reduce Deaths From Opioid Overdose

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Medical marijuana laws that include a "liberal" allowance of the drug to dispensaries may contribute to reducing opioid overdose-related deaths in Medicare Part-D and Medicaid beneficiaries.

Clinical Trials May Overestimate Benefits of Cannabis Therapy

Clinical Trials May Overestimate Benefits of Cannabis Therapy

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The benefits associated with medical cannabis therapy may be overestimated due to inadequate blinding in clinical trials.

Medical Marijuana Laws Increasing Illicit Cannabis Use Among Adults

Medical Marijuana Laws Increasing Illicit Cannabis Use Among Adults

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Medical marijuana laws may be connected to increased rates of illicit cannabis use and cannabis use disorder, leading some users to experience negative consequences, such as motor vehicle accidents.

Cannabinoids May Provide Limited Relief From Neuropathic Pain

Cannabinoids May Provide Limited Relief From Neuropathic Pain

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Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.

Cannabinoids May Provide Limited Relief From Neuropathic Pain

Cannabinoids May Provide Limited Relief From Neuropathic Pain

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Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.

Cannabis for Medicine: Research and Policies Needed

Cannabis for Medicine: Research and Policies Needed

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Medical marijuana, as a botanical and a scheduled drug does not fit the FDA paradigm for drug approval, a major impediment to its use in research.

Effect of Legalization of Medical Marijuana on Illicit Use

Effect of Legalization of Medical Marijuana on Illicit Use

Cannabis use disorder is also rising faster in states with legalization laws

National Academies Report on Health Effects of Cannabis

National Academies Report on Health Effects of Cannabis

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In January 2017, the National Academies of Sciences, Engineering, and Medicine released a report titled "The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendation for Research."

Crystal Structure of Cannabinoid Receptor 1 Resolved: Implications for Pain Management

Crystal Structure of Cannabinoid Receptor 1 Resolved: Implications for Pain Management

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"The utility of the crystal structure may provide inspiration for drug design toward refining efficacy and avoiding adverse events."

Legalized Marijuana: Are We Ready for the Consequences?

Legalized Marijuana: Are We Ready for the Consequences?

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Pot-related poison control calls and hospital discharges spike with wider availability.

5 Pain Stories You Might Have Missed, Aug. 26

5 Pain Stories You Might Have Missed, Aug. 26

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Every day the staff at Clinical Pain Advisor browses the Web for stories on chronic pain, acute pain, low back pain, diabetic neuropathy, fibromyalgia and other painful health conditions that readers might have missed the day before and lists some of their favorite articles in a daily column to provide clinicians with a resource they can check first thing in the morning.

Should Medical Marijuana Be Used To Treat Epileptic Children?

Should Medical Marijuana Be Used To Treat Epileptic Children?

Some parents are now demanding that politicians and state legislators legalize the use of marijuana for treating epileptic children.

Cannabinoid-Focused Pharma Company Echo Releases Initial Clinical Trial Results

Cannabinoid-Focused Pharma Company Echo Releases Initial Clinical Trial Results

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For Echo, reducing the therapeutic dose is key to improving compliance and providing both patients and healthcare providers with a more cost-effective therapy.

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