HealthDay News — A novel method of short-term percutaneous peripheral nerve stimulation (PNS) is useful for producing pain relief and reducing medication use among patients with chronic low back pain (LBP), according to a case report published in Pain Practice.1
Leonardo Kapural, MD, PhD, from the Center for Clinical Research and Carolina’s Pain Institute in Winston Salem, NC, and colleagues describe the use of PNS in 2 subjects with chronic LBP. Stimulation was discontinued at the end of the 1-month therapy and the leads were withdrawn.
The authors note that PNS produced clinically significant improvements in pain and functional outcomes (62% average reduction in Brief Pain Inventory Question #5, average pain; 73% reduction in disability, Oswestry Disability Index; 83% reduction in pain interference, Brief Pain Inventory). Non-opioid analgesic use was reduced by 83% on average, and the subject taking opioids ceased opioid use. Minor skin irritation caused by a topical dressing was the only adverse event. For at least 4 months after the start of therapy, clinically significant improvements were sustained (79% average reduction in pain; both reported minimal disability; and 100 and 74% reductions in opioids and non-opioids, respectively).
“This therapy has the potential to shift the paradigm in the management of chronic pain, offering a minimally invasive treatment with the potential to bring the benefits of an effective neuromodulation therapy to patients earlier in the treatment continuum,” the authors write.
Several authors disclosed financial ties to SPR Therapeutics, which funded the study. Several authors are listed as inventors on issued or pending patents.
- Kapural L, Gilmore CA, Chae J, et al. Percutaneous Peripheral Nerve Stimulation for the Treatment of Chronic Low Back Pain: Two Clinical Case Reports of Sustained Pain Relief. Pain Pract. 2017. doi: 10.1111/papr.12571