Sheila Jacobs

The investigators sought to evaluate whether early-life traumatic experiences, stressful life events, and alexithymia are associated with chronic migraine and medication overuse headache.

Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Outcomes were examined in 2 randomized, double-blind, placebo-controlled, parallel-group clinical trials: PIONEER I (ClinicalTrials.gov identifier: NCT01468207) and PIONEER II (ClinicalTrials.gov identifier: NCT01468233).

Investigators sought to evaluate intra-articular onabotulinumtoxinA 400 U and 200 U in reducing symptoms of knee OA in patients with nociceptive pain.

Researchers sought to confirm whether concomitant fibromyalgia has a negative effect on TNF blocker response.

Patients with knee osteoarthritis who can best benefit from treatment with intra-articular hyaluronic acid injections include patients with high levels of knee pain, younger individuals, persons with a high body mass index, and individuals with less severe structural damage.

The effects of glucosamine supplements in the treatment of patients with painful temporomandibular joint osteoarthritis were not superior to the effects of ibuprofen taken 2 to 3 times per day.

Chronic pain experienced by patients with pachyonychia congenita may be caused by damage to the peripheral nerve fibers, with the hyperalgesia and allodynia observed in affected regions likely to be manifestations of peripheral sensitization.

The use of intranasal sumatriptan is an effective treatment for patients with acute migraine attacks; however, future investigations are needed to better understand differences in routes of administration and other therapies for migraine.

Children who experience any type of recurrent headache at school entry are at an increased risk for the development of headaches in young adulthood.