Shannon Aymes

People who live at high altitudes may experience increase migraine prevalence, duration, and severity of migraine.

Long-term treatment with opioids is associated with more adverse outcomes in patients with polyneuropathy, including depression, overdose, and opioid dependence.

Mindfulness meditation is associated with improvements in quality-of-life measures, depression, and anxiety over time compared with usual care in patients with ALS.

A significant decrease in migraine frequency was observed; however, it is not clear how large a role placebo effect plays in treatment response.

Abstaining from caffeine was associated with excellent acute treatment efficacy.