Crystal Wong, MD

The World Health Organization published new guidelines for managing HIV drug resistance in countries in which pretreatment HIV drug resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) is prevalent.

Patients with acute onset of severe headache should undergo diagnostic testing for subarachnoid hemorrhage, a potentially dangerous cause of headache, if the minimum duration of headache is present.

In patients with severe chronic pain refractory to conventional therapy, intrathecal ziconotide provided long-term pain relief, particularly when used as first-line intrathecal therapy.

Underlying synovitis and enthesitis may go undetected in clinical findings, but can be detected by power Doppler ultrasounds.

Trigger point injection as an adjunct to physical therapy is well tolerated and improves symptoms of pelvic floor muscle spasm in approximately 50% of patients with chronic prostatitis/chronic pelvic pain syndrome.

The extended-release formulation of tramadol was shown to be as effective as buprenorphine and more effective than clonidine for treating symptoms of opioid withdrawal.

Overall blood flow velocity remains unchanged during migraine headache, although blood flow velocity may be decreased early on in the attack.

The cerebrospinal fluid of patients with vs without intervertebral disc degeneration with and without low back pain was shown to differentially express proteins involved in inflammation and nerve injury.

Cilostazol triggers migraine-like attacks in patients with migraine without aura in a reproducible manner.

In patients undergoing total knee arthroplasty, sciatic nerve block plus femoral nerve block was more effective for pain relief than local infiltration analgesia plus femoral nerve block.