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TRULANCE
Constipation and bowel cleansers
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Drug Name:

TRULANCE Rx

Generic Name and Formulations:
Plecanatide 3mg; tabs.

Company:
Synergy Pharmaceuticals, Inc.

Therapeutic Use:

Indications for TRULANCE:

Chronic idiopathic constipation (CIC).

Adult:

Take with or without food. Swallow whole; if difficulties in swallowing, may crush tabs and mix in applesauce or water; may also give with water via NG or gastric feeding tube. ≥18yrs: 3mg once daily.

Children:

<18yrs: not established (<6yrs: contraindicated; 6–<18yrs: avoid).

Contraindications:

Children <6yrs old. Known or suspected mechanical GI obstruction.

Warnings/Precautions:

Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.

Pharmacological Class:

Guanylate cyclase-C agonist.

Adverse Reactions:

Diarrhea (may be severe), sinusitis, upper respiratory tract infection, abdominal distension, flatulence, abdominal tenderness, increased liver enzymes.

Generic Availability:

NO

How Supplied:

Tabs—30

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