Preliminary Diagnosis: Gout I. What imaging technique is first-line for this diagnosis? Plain radiographs II. Describe the advantages and disadvantages of this technique for diagnosis of gout. Advantages Clearly visualizes dense gouty tophi and osseous erosions Clearly visualizes overhanging cortical edges and juxtaarticular erosions extending perpendicularly from the underlying boneContinue Reading Disadvantages Radiographs often normal…
I. What every physician needs to know. Gout is a rheumatologic disorder characterized by supersaturation of uric acid in the serum (hyperuricemia) accompanied by attacks of acute, markedly painful monoarticular or polyarticular joint inflammation. Humans lack the enzyme uricase (breaks down uric acid into allantoin); consequently, our serum uric acid levels are close to the…
A diagnosis of incident or new chronic pain may be twice as likely in patients with vs without gout.
Eighty-nine percent of admissions (50 patients) met the definition of being preventable.
High serum uric acid levels are associated with a high risk of new-onset gout and gout recurrence, while lowering SUA levels can significantly reduce incident and recurrent gout.
Gout increased the risk of erectile dysfunction in men by 21%.
Does this patient have Gout? Gout is a disease resulting from deposition of monosodium urate (MSU) crystals in the joints and connective soft-tissues in the setting of sustained hyperuricemia (serum uric acid >6.8 mg/dL). Classically, the initial manifestation of gout is acute monoarthritis characterized with abrupt onset of exquisite pain and swelling of the joint…
Researchers provided participants in the intervention group with gout education, podiatric care, and an athletic shoe, and participants in the control arm received only gout education and podiatric care.
According to guidelines published by the American College of Rheumataology (ACR), CKD is an indication for urate-lowering therapy (ULT) in patients with a history of gout attacks or hyperuricemia
The incidence of gout among CKD patients was 6.82 per 1,000 persons per year compared to 2.43 for those without the disease.