The Sjögren's Syndrome Foundation has released the first clinical practice guidelines for the disease, which includes recommendations on the management of fatigue, inflammatory musculoskeletal pain, and use of biologic agents.
There is little evidence to support the utility of biomarkers to guide clinical care for optimal RA treatment.
There is a need for caution when extrapolating trial results to use in the day-to-day management of patients with RA.
Mean percentage of increase in the HDL and LDL cholesterol levels was higher among patients receiving tofacitinib 5 mg twice daily and those receiving tofacitinib 10 mg twice daily.
DMARDs alone or with methotrexate and tofacitinib plus methotrexate improved disease activity and remission rates in patients with RA who have not responded to previous biologic therapy.
Are You Sure the Patient Has Rheumatoid Arthritis? Revised American Rheumatology Association Criteria for the Classification of Rheumatoid Arthritis (RA): For classification purposes, a patient is said to have RA if he or she has satisfied at least 4 of the following 7 criteria. Criteria 1 through 4 must have been present for at least…
Nearly one-third of novel therapies have a post-market safety event.
Hospital Infection Control
How does laboratory safety impact infection control? While laboratory safety is primarily intended to prevent morbidity due to infections in laboratory workers, laboratory-associated infections (LAIs) may furthermore impact public health, as it was shown in one of the cases with laboratory-acquired SARS, leading to secondary cases in the community, at a time the pandemic had…
I. What every physician needs to know. This inflammatory disorder characterized by daily high fevers, arthritis, and an evanescent rash in children was originally described in 1896 by George Still. Since then, it has been known by various other names in adults: Adult-onset Still’s disease (AOSD) Adult juvenile rheumatoid arthritis (adult JRA) – in the…
Are You Confident of the Diagnosis? What should you be alert for in the patient’s history? Interstitial granulomatous dermatitis (IGD) encompasses a heterogeneous group of skin eruption. It was initially described as cutaneous lesions that are more commonly seen in patients with rheumatoid arthritis and other autoimmune diseases. Later on, a variety of drug therapies…