Rheumatology

Detecting Cognitive Dysfunction in Systemic Lupus Erythematosus

Detecting Cognitive Dysfunction in Systemic Lupus Erythematosus

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The Montreal Cognitive Assessment is superior to the Mini-Mental State Examination at detecting cognitive dysfunction in SLE.

Lesinurad Plus Febuxostat Effective for Tophaceous Gout

Lesinurad Plus Febuxostat Effective for Tophaceous Gout

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Lesinurad combined with febuxostat showed superior serum urate reduction vs febuxostat alone in patients with tophaceous gout requiring additional therapy.

Dose-Dependent ACR20 Response Rates in RA With Peficitinib

Dose-Dependent ACR20 Response Rates in RA With Peficitinib

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Use of the JAK inhibitor peficitinib in combination with certain csDMARDs results in a dose-dependent ACR20 response rate in patients with RA over 12 weeks.

Diagnostic Value of MRI for Unclassified Arthritis

Diagnostic Value of MRI for Unclassified Arthritis

MRI may assist in identifying patients with unclassified arthritis who will develop rheumatoid arthritis (RA) — primarily in patients with UA presenting with oligoarthritis.

Association Between Osteoporosis and Multiple Sclerosis

Association Between Osteoporosis and Multiple Sclerosis

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Patients with multiple sclerosis (MS) have lower bone mineral density and greater rates of osteoporosis than healthy controls.

Low Disease Activity in Rheumatoid Arthritis After Tofacitinib Discontinuation

Low Disease Activity in Rheumatoid Arthritis After Tofacitinib Discontinuation

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Approximately 1 in 3 patients with RA who discontinued tofacitinib maintained low disease activity after 1 year.

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

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Muscle MRI may complement a physician's objective assessment in juvenile dermatomyositis, although negative MRI findings should not preclude treatment continuation.

Gout Prevention With Dietary Intervention

Gout Prevention With Dietary Intervention

The Dietary Approaches to Stop Hypertension (DASH) diet is effective for prevention of gout.

Serum Uric Acid Levels Associated With Gout Risk

Serum Uric Acid Levels Associated With Gout Risk

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High serum uric acid levels are associated with a high risk of new-onset gout and gout recurrence, while lowering SUA levels can significantly reduce incident and recurrent gout.

Concern Regarding Legislation Allowing Substitution of Biosimilars for Branded Drugs

Concern Regarding Legislation Allowing Substitution of Biosimilars for Branded Drugs

Much concern has been voiced regarding legislation allowing the substitution of biosimilars for branded drugs.

Alterations in Soluble Mediators May Predict Transition to Lupus

Alterations in Soluble Mediators May Predict Transition to Lupus

Preclinical alterations in levels of soluble mediators may predict transition to SLE for unaffected relatives of patients with SLE.

Rheumatoid Arthritis Treatment: Baricitinib Superior to Adalimumab

Rheumatoid Arthritis Treatment: Baricitinib Superior to Adalimumab

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This study included phase 3 trial in patients taking baricitinib, adalimumab, or placebo in addition to methotrexate background therapy.

Secukinumab Improves Symptoms in TNFi-Refractory Rheumatoid Arthritis

Secukinumab Improves Symptoms in TNFi-Refractory Rheumatoid Arthritis

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A phase 3, double-blind, randomized placebo-controlled study was conducted in 551 patients with active RA who received secukinumab, abatacept, or placebo.

Lupus: Improving Symptoms and Outcomes With Diet and Nutrition

Lupus: Improving Symptoms and Outcomes With Diet and Nutrition

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Consuming adequate amounts of the right nutrients can help relieve symptoms and improve outcomes in patients with systemic lupus erythematosus.

Bridging Gaps in Patient Access to Rheumatologists With Telemedicine

Bridging Gaps in Patient Access to Rheumatologists With Telemedicine

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Telerheumatology can improve healthcare access, patient outcomes, and costs

A Central Referral Triage System to Improve Access to Rheumatology Care

A Central Referral Triage System to Improve Access to Rheumatology Care

The innovative triage and referral system introduced by CReATe Rheum successfully facilitated timely access to care for rheumatology patients. Further long-term follow-up demonstrated that, despite an increasing number of referrals, CReATe Rheum can accurately cope with increased demand.

Johns Hopkins Pain Physician: on the Need for an Inter-Disciplinary Approach to Pain Management

Johns Hopkins Pain Physician: on the Need for an Inter-Disciplinary Approach to Pain Management

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"As [a member] of the NIH Task Force on pain, I would say that one of the things that's important to show is that an interdisciplinary model and a multimodal approach are effective and cost-effective, as they certainly are expensive."

Rheumatologists and Dermatologists Need to Work Together to Treat Psoriatic Arthritis

Rheumatologists and Dermatologists Need to Work Together to Treat Psoriatic Arthritis

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Dermatologists are in a key position to screen for psoriatic arthritis (PsA), as the overlapping and variable symptoms of the disease require multidisciplinary care.

Accelerated Knee OA: Lowering the Risk in Patients

Accelerated Knee OA: Lowering the Risk in Patients

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OA is traditionally thought of as a slowly progressive disorder, but 3% to 4% of individuals at risk for OA develop it in less than 4 years and some in less than 12 months. Individuals who are older, overweight, and/or have a new knee injury are more likely to develop this accelerated form of knee OA

Can Foot Synovitis In RA Predict Unstable Long-Term Remission?

Can Foot Synovitis In RA Predict Unstable Long-Term Remission?

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Foot synovitis may predict patients who are at higher risk of unstable rheumatoid arthritis (RA) remission.

Incidence, Risk Factors for Psoriatic Arthritis in Patients With Psoriasis

Incidence, Risk Factors for Psoriatic Arthritis in Patients With Psoriasis

Variables linked to PsA development include severe psoriasis, low level of education, retinoid use.

Should CVD Risk Assessment Algorithms for RA Be Updated?

Should CVD Risk Assessment Algorithms for RA Be Updated?

A new study published suggests that it may be time to produce new algorithms for assessing cardiovascular disease risk in patients with rheumatoid arthritis.

FDA Approves Inflectra, a Biosimilar Version of Remicade

FDA Approves Inflectra, a Biosimilar Version of Remicade

For adults with Crohn's, rheumatoid arthritis, or psoriasis.

Pain, Physical Function Improve After Bariatric Surgery

Pain, Physical Function Improve After Bariatric Surgery

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New research suggests that patients with severe obesity who undergo bariatric surgery experience improvements in pain, physical function, and walking capacity over 3 years.

Patient-Reported Outcomes: A New Paradigm for Evaluating Fibromyalgia

Patient-Reported Outcomes: A New Paradigm for Evaluating Fibromyalgia

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Self-report measures capture the complex nature of this debilitating, chronic condition.

New Payment System for Joint Replacements

New Payment System for Joint Replacements

Focus will be on quality of care and cost cutting; hospitals on board but orthopedic surgeons are wary.

PNBs Associated With Improved Outcomes in Hip, Knee Arthroplasty

PNBs Associated With Improved Outcomes in Hip, Knee Arthroplasty

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New research suggests that PNBs are linked to better medical and economic outcomes in patients receiving hip and knee replacement.

Is RA Among Preop Predictors of Hospital Readmission Following THR?

Is RA Among Preop Predictors of Hospital Readmission Following THR?

The use of a postoperative risk stratification model can serve to reduce the costs associated with hospital readmission by identifying patients with specific risk factors.

Pain Pharmacotherapy Changes For RA During Pregnancy

Pain Pharmacotherapy Changes For RA During Pregnancy

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The pregnant patient with rheumatoid arthritis may need to have pain medication changed due to potential effects on the fetus.

Serotonin Plays Fundamental Role in Rheumatoid Arthritis

Serotonin Plays Fundamental Role in Rheumatoid Arthritis

Serotonin shows it plays a fundamental role in RA through regulation of the Th17/T-regulatory cell balance.

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