Rheumatology

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

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Pain may partly mediate the observed association between physical performance and depressive symptoms in patients with radiographic knee osteoarthritis.

Rheumatologist-Assessed vs Criteria for Inflammatory Back Pain in Psoriatic Arthritis

Rheumatologist-Assessed vs Criteria for Inflammatory Back Pain in Psoriatic Arthritis

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Rheumatologist-assessed inflammatory back pain (IBP) or the criteria for IBP developed for ankylosing spondylitis might not perform well when determining axial involvement in psoriatic arthritis.

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

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Replacing at least 10 minutes a day of time spent sedentary, asleep, or in light physical activity with moderate physical activity may be associated with significant reductions in bodily pain interference and knee pain in adults at risk for osteoarthritis knee pain.

EULAR Releases 2018 Recommendations for the Management of Hand Osteoarthritis

EULAR Releases 2018 Recommendations for the Management of Hand Osteoarthritis

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EULAR has released updated guidelines for the management of hand osteoarthritis.

Gender Differences, Clinical Outcomes of Pain in Axial Spondyloarthritis

Gender Differences, Clinical Outcomes of Pain in Axial Spondyloarthritis

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The location and spread of pain in patients with axial spondyloarthritis was different between genders and was related to worse clinical status.

Inflammatory Back Pain and Neuropathic Pain May Affect Axial Spondyloarthritis Outcomes

Inflammatory Back Pain and Neuropathic Pain May Affect Axial Spondyloarthritis Outcomes

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Patients with axial spondyloarthritis who have inflammatory back pain or neuropathic pain may have higher pain intensity, pain interference, disease activity, and greater functional limitation compared with individuals with axial spondyloarthritis but without either comorbidity.

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

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Buckling of the hip joint, also referred to as "giving way," and hip injuries may be associated with hip pain worsening in patients with symptomatic hip osteoarthritis.

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

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Change in pain and physical function score from baseline were chosen as the co-primary endpoints.

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

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The reliability of retrospective and daily pain measurements was comparable among patients with hip osteoarthritis, except in individuals with severe intermittent pain for whom retrospective measurements may be less reliable.

Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation

Pain Catastrophizing Decreases in Rheumatoid Arthritis After DMARD Initiation

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Pain catastrophizing decreases over time in patients with RA who respond to DMARD treatment.

Exploring the Clinical Implications of Cannabinoid Use in Rheumatoid Arthritis

Exploring the Clinical Implications of Cannabinoid Use in Rheumatoid Arthritis

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Preliminary evidence has found an association between the cannabinoid system and other rheumatic conditions, but the studies have not provided conclusive results that could drive recommendations.

DAS28 Patient-Reported Components Identify Fibromyalgia in Rheumatoid Arthritis

DAS28 Patient-Reported Components Identify Fibromyalgia in Rheumatoid Arthritis

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The assessment of patient-reported components of the DAS28 can be a useful way to identify patients with fibromyalgic RA.

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

Widespread Pain Common, Linked to Worse Patient-Reported Disease Activity in PsA

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Widespread nonarthritic pain is linked to worse patient-reported and composite psoriatic arthritis activity measures.

Multiple Factors to Consider When Selecting NSAID for Arthritis

Multiple Factors to Consider When Selecting NSAID for Arthritis

Factors to be considered when choosing the correct nonsteroidal anti-inflammatory drug (NSAID) for arthritis include effectiveness, concurrent health conditions, and frequency of use.

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

Increased Rates of Opioid- and Injection Drug Use-Related Septic Knee Arthritis

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The percentage of patients with septic arthritis related to opioid or injection drug use was found to have increased from 2000 to 2013.

Efficacy, Safety of OnabotulinumtoxinA Assessed for Knee OA Treatment

Efficacy, Safety of OnabotulinumtoxinA Assessed for Knee OA Treatment

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Investigators sought to evaluate intra-articular onabotulinumtoxinA 400 U and 200 U in reducing symptoms of knee OA in patients with nociceptive pain.

Consensi Approved to Treat Hypertension and Osteoarthritis Pain

Consensi Approved to Treat Hypertension and Osteoarthritis Pain

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Consensi combines amlodipine besylate, a calcium-channel blocker (CCB), and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID).

Pain, Cognitive Dysfunction in SLE Mediated by Sleep Disturbance, Depression

Pain, Cognitive Dysfunction in SLE Mediated by Sleep Disturbance, Depression

The relationship between pain and cognitive dysfunction was explained by sleep disturbance and depressive symptoms.

Illness Perceptions Mediate Back Pain, Quality of Life in Early Axial Spondyloarthritis

Illness Perceptions Mediate Back Pain, Quality of Life in Early Axial Spondyloarthritis

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Illness perceptions are important in the relationship between back pain and health-related quality of life in patients suspected of axial spondyloarthritis.

Depressive Symptoms Predict Future Pain, Disability in Adolescent JIA

Depressive Symptoms Predict Future Pain, Disability in Adolescent JIA

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Baseline depressive symptoms were associated with pain and disability in adolescents with juvenile idiopathic arthritis.

Risks Associated With Co-Administration of Aspirin and Other NSAIDs

Risks Associated With Co-Administration of Aspirin and Other NSAIDs

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In patients with rheumatoid arthritis or osteoarthritis who are at higher risk for cardiovascular events, celecoxib may be safer compared with naproxen or ibuprofen when these drugs are taken alone or in combination with aspirin.

Influence of Psychosocial, Sociodemographic Factors on Knee Osteoarthritis-Associated Pain

Influence of Psychosocial, Sociodemographic Factors on Knee Osteoarthritis-Associated Pain

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A set of psychosocial and sociodemographic factors may be associated with pain levels in patients with knee osteoarthritis.

Zilretta Benefits 'Real-World' Patients With Knee OA, Says Study

Zilretta Benefits 'Real-World' Patients With Knee OA, Says Study

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Patients who received a repeat Zilretta injection experienced a 64% improvement in Western Ontario and McMaster Universities Arthritis Index (WOMAC)-A (pain), a 66% improvement in WOMAC-B (stiffness), a 64% improvement on WOMAC-C (function), and improvement represented by a doubling of the KOOS Quality of Life subscale score by Week 4.

Guidelines for Biosimilar Use for Treatment of Rheumatologic Diseases

Guidelines for Biosimilar Use for Treatment of Rheumatologic Diseases

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Consensus recommendations on the use of biosimilars for the treatment of patients with rheumatologic diseases were recently published in Annals of the Rheumatic Diseases.

Ketoprofen Safe, Effective Pain Management for Rheumatoid Arthritis

Ketoprofen Safe, Effective Pain Management for Rheumatoid Arthritis

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Ketoprofen was found to be effective in relieving moderate to severe pain in patients with rheumatoid arthritis.

No Increased Risk of SLE With Current Use of Statin Therapy

No Increased Risk of SLE With Current Use of Statin Therapy

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No association was found between current statin use and the risk of developing systemic lupus erythematosus.

SLE Disease Flares Associated With Childhood Diffuse Alveolar Hemorrhage

SLE Disease Flares Associated With Childhood Diffuse Alveolar Hemorrhage

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Diffuse alveolar hemorrhage in childhood-onset SLE is associated with serious disease flares, and is complicated by sepsis and high mortality rate.

New SLE Candidate Criteria

New SLE Candidate Criteria

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Researchers have created a set of 21 candidate criteria for systemic lupus erythematosus as apart of a multiphase development of a set of criteria for the disease.

FDA Approves Duzallo, Lesinurad Plus Allopurinol Combo Drug, for Gout

FDA Approves Duzallo, Lesinurad Plus Allopurinol Combo Drug, for Gout

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The FDA approved Duzallo, a fixed-dose tablet combining lesinurad and allopurinol, for the treatment of uncontrolled gout.

Disease Activity Biomarker in Pediatric SLE

Disease Activity Biomarker in Pediatric SLE

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Fractional exhaled nitric oxide monitoring may provide a potential biomarker of disease activity and signify the emergency of pulmonary involvement in children with SLE.

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