Rheumatology

Disease Activity Biomarker in Pediatric SLE

Disease Activity Biomarker in Pediatric SLE

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Fractional exhaled nitric oxide monitoring may provide a potential biomarker of disease activity and signify the emergency of pulmonary involvement in children with SLE.

Certain Osteoporotic Drugs Effective in Preventing Secondary Vertebral Fractures

Certain Osteoporotic Drugs Effective in Preventing Secondary Vertebral Fractures

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Clinicians who treat osteoporotic fractures should prescribe anti-osteoporotic drugs to prevent secondary vertebral and non-vertebral fractures.

Synovitis Detected by Ultrasound in Psoriatic Arthritis in Remission

Synovitis Detected by Ultrasound in Psoriatic Arthritis in Remission

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Underlying synovitis and enthesitis may go undetected in clinical findings, but can be detected by power Doppler ultrasounds.

Association Between Low Levels of Blimp-1 Protein, Lupus

Association Between Low Levels of Blimp-1 Protein, Lupus

Researchers from the Feinstein Institute for Medical Research may have identified a potential cause for lupus, which may lead to new treatment options.

Biomarkers of Increased PAH Risk Identified in Patients With SLE

Biomarkers of Increased PAH Risk Identified in Patients With SLE

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The risk for death associated with SLE remains high for patients with SLE-associated PAH and researchers have identified the biomarkers that may lead to early detection.

Early CVD Detection in Patients With RA: Expert Insight

Early CVD Detection in Patients With RA: Expert Insight

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Patients with RA have a significantly higher risk of cardiovascular disease, and cardiac magnetic resonance can help with early diagnosis.

Disease Activity on Foot MRI Despite Clinical Remission in Rheumatoid Arthritis

Disease Activity on Foot MRI Despite Clinical Remission in Rheumatoid Arthritis

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A sizeable percentage of patients with rheumatoid arthritis who are in clinical remission have evidence of disease activity on magnetic resonance imaging of the foot that is mostly affected.

Fish Consumption May Reduce RA Symptoms

Fish Consumption May Reduce RA Symptoms

Eating fish at least twice a week may significantly reduce the pain and swelling associated with rheumatoid arthritis.

Lesinurad Plus Febuxostat for Tophaceous Gout

Lesinurad Plus Febuxostat for Tophaceous Gout

In patients with tophaceous gout, combination therapy of lesinurad plus febuxostat is more effective at reducing serum urate levels than febuxostat monotherapy.

Risk Factor for Osteonecrosis in Patients With SLE

Risk Factor for Osteonecrosis in Patients With SLE

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Cumulative steroid dosage is a risk factor for the development of osteonecrosis, which is the most frequent type of damage in lupus patients.

Opioid Use Patterns in Rheumatoid Arthritis

Opioid Use Patterns in Rheumatoid Arthritis

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Longitudinal opioid prescribing patterns suggest that regular use among patients with rheumatoid arthritis (RA) is slightly declining.

Subcutaneous Belimumab Effective on SLE

Subcutaneous Belimumab Effective on SLE

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Adjunctive subcutaneous belimumab plus standard care improves SLE Responder Index response and decreases disease flares

Detecting Cognitive Dysfunction in Systemic Lupus Erythematosus

Detecting Cognitive Dysfunction in Systemic Lupus Erythematosus

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The Montreal Cognitive Assessment is superior to the Mini-Mental State Examination at detecting cognitive dysfunction in SLE.

Lesinurad Plus Febuxostat Effective for Tophaceous Gout

Lesinurad Plus Febuxostat Effective for Tophaceous Gout

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Lesinurad combined with febuxostat showed superior serum urate reduction vs febuxostat alone in patients with tophaceous gout requiring additional therapy.

Dose-Dependent ACR20 Response Rates in RA With Peficitinib

Dose-Dependent ACR20 Response Rates in RA With Peficitinib

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Use of the JAK inhibitor peficitinib in combination with certain csDMARDs results in a dose-dependent ACR20 response rate in patients with RA over 12 weeks.

Diagnostic Value of MRI for Unclassified Arthritis

Diagnostic Value of MRI for Unclassified Arthritis

MRI may assist in identifying patients with unclassified arthritis who will develop rheumatoid arthritis (RA) — primarily in patients with UA presenting with oligoarthritis.

Association Between Osteoporosis and Multiple Sclerosis

Association Between Osteoporosis and Multiple Sclerosis

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Patients with multiple sclerosis (MS) have lower bone mineral density and greater rates of osteoporosis than healthy controls.

Low Disease Activity in Rheumatoid Arthritis After Tofacitinib Discontinuation

Low Disease Activity in Rheumatoid Arthritis After Tofacitinib Discontinuation

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Approximately 1 in 3 patients with RA who discontinued tofacitinib maintained low disease activity after 1 year.

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

Additional Tool for Juvenile Dermatomyositis Diagnosis: Muscle MRI

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Muscle MRI may complement a physician's objective assessment in juvenile dermatomyositis, although negative MRI findings should not preclude treatment continuation.

Gout Prevention With Dietary Intervention

Gout Prevention With Dietary Intervention

The Dietary Approaches to Stop Hypertension (DASH) diet is effective for prevention of gout.

Serum Uric Acid Levels Associated With Gout Risk

Serum Uric Acid Levels Associated With Gout Risk

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High serum uric acid levels are associated with a high risk of new-onset gout and gout recurrence, while lowering SUA levels can significantly reduce incident and recurrent gout.

Concern Regarding Legislation Allowing Substitution of Biosimilars for Branded Drugs

Concern Regarding Legislation Allowing Substitution of Biosimilars for Branded Drugs

Much concern has been voiced regarding legislation allowing the substitution of biosimilars for branded drugs.

Alterations in Soluble Mediators May Predict Transition to Lupus

Alterations in Soluble Mediators May Predict Transition to Lupus

Preclinical alterations in levels of soluble mediators may predict transition to SLE for unaffected relatives of patients with SLE.

Rheumatoid Arthritis Treatment: Baricitinib Superior to Adalimumab

Rheumatoid Arthritis Treatment: Baricitinib Superior to Adalimumab

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This study included phase 3 trial in patients taking baricitinib, adalimumab, or placebo in addition to methotrexate background therapy.

Secukinumab Improves Symptoms in TNFi-Refractory Rheumatoid Arthritis

Secukinumab Improves Symptoms in TNFi-Refractory Rheumatoid Arthritis

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A phase 3, double-blind, randomized placebo-controlled study was conducted in 551 patients with active RA who received secukinumab, abatacept, or placebo.

Lupus: Improving Symptoms and Outcomes With Diet and Nutrition

Lupus: Improving Symptoms and Outcomes With Diet and Nutrition

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Consuming adequate amounts of the right nutrients can help relieve symptoms and improve outcomes in patients with systemic lupus erythematosus.

Bridging Gaps in Patient Access to Rheumatologists With Telemedicine

Bridging Gaps in Patient Access to Rheumatologists With Telemedicine

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Telerheumatology can improve healthcare access, patient outcomes, and costs

A Central Referral Triage System to Improve Access to Rheumatology Care

A Central Referral Triage System to Improve Access to Rheumatology Care

The innovative triage and referral system introduced by CReATe Rheum successfully facilitated timely access to care for rheumatology patients. Further long-term follow-up demonstrated that, despite an increasing number of referrals, CReATe Rheum can accurately cope with increased demand.

Johns Hopkins Pain Physician: on the Need for an Inter-Disciplinary Approach to Pain Management

Johns Hopkins Pain Physician: on the Need for an Inter-Disciplinary Approach to Pain Management

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"As [a member] of the NIH Task Force on pain, I would say that one of the things that's important to show is that an interdisciplinary model and a multimodal approach are effective and cost-effective, as they certainly are expensive."

Rheumatologists and Dermatologists Need to Work Together to Treat Psoriatic Arthritis

Rheumatologists and Dermatologists Need to Work Together to Treat Psoriatic Arthritis

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Dermatologists are in a key position to screen for psoriatic arthritis (PsA), as the overlapping and variable symptoms of the disease require multidisciplinary care.

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