Rheumatic Arthritis

Kevzara Injection Gets FDA Approval for Rheumatoid Arthritis

Kevzara Injection Gets FDA Approval for Rheumatoid Arthritis

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Regeneron and Sanofi announced that the FDA has approved Kevzara (sarilumab) injection to treat adults with moderate to severe rheumatoid arthritis.

Glucocorticoids for Early Rheumatoid Arthritis: Assessing Long-term Safety

Glucocorticoids for Early Rheumatoid Arthritis: Assessing Long-term Safety

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Patients with early RA treated with very low-dose glucocorticoids over 7 years experienced similar toxicity as patients who were not treated with glucocorticoids.

Tofacitinib Compared With Adalimumab in RA Study

Tofacitinib Compared With Adalimumab in RA Study

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Pfizer has announced top-line results from its Phase 3B/4 study comparing treatment with Xeljanz to adalimumab in patients with moderate to severe rheumatoid arthritis.

Severe Arthritis Complaints & Medical Marijuana Use

Severe Arthritis Complaints & Medical Marijuana Use

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This low rate of use in rheumatology patients is in stark contrast to the high rates of severe arthritis frequently reported by medicinal marijuana users.

Predicting Arthritis Progression in Patients With Arthralgia

Predicting Arthritis Progression in Patients With Arthralgia

"Within patients with clinically suspect arthralgia, anti-citrullinated protein antibody was associated with increased risks on progression to clinical arthritis."

Patient-Reported Outcomes Correlate With DAS28 Scores in RA

Patient-Reported Outcomes Correlate With DAS28 Scores in RA

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"Improved pain management should be explored in patients who report high disease activity."

Biomarker Profiles Improve RA Relapse Predictions During DMARD Taper

Biomarker Profiles Improve RA Relapse Predictions During DMARD Taper

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MBDA scores combined with ACPA testing allowed researchers to predict RA relapse in more than 80% of patients.

Assessing Risk for Cardiovascular Disease in Rheumatoid Arthritis

Assessing Risk for Cardiovascular Disease in Rheumatoid Arthritis

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Rheumatology Advisor speaks with Erin Michos, MD, cardiologist at Johns Hopkins School of Medicine, and Eric Matteson, MD, rheumatologist at Mayo Clinic, about refining cardiovascular risk assessment in patients with rheumatoid arthritis.

Biosimilar Drug Erelzi Approved by FDA for Rheumatoid Arthritis

Biosimilar Drug Erelzi Approved by FDA for Rheumatoid Arthritis

Erelzi, a biosimilar for Enbrel, treats rheumatoid arthritis and other inflammatory diseases.

Reassessing the Efficacy of Gold Therapy for Rheumatoid Arthritis

Reassessing the Efficacy of Gold Therapy for Rheumatoid Arthritis

Significant clinical improvement was reported after adding intramuscular gold therapy to methotrexate.

Benefits of Intensive Pain Control in Early Rheumatoid Arthritis

Benefits of Intensive Pain Control in Early Rheumatoid Arthritis

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Much of the disability associated with RA relates to the pain secondary to inflammatory joint inflammation.

Autoantibodies Mediating Autoimmune Disorders-Associated Pain

Autoantibodies Mediating Autoimmune Disorders-Associated Pain

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Once we better understand the role of each disease's specific autoantibody and how they are causing pain, we can move on to developing targeted therapies.

Can Foot Synovitis In RA Predict Unstable Long-Term Remission?

Can Foot Synovitis In RA Predict Unstable Long-Term Remission?

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Foot synovitis may predict patients who are at higher risk of unstable rheumatoid arthritis (RA) remission.

Can Foot Synovitis in RA Help Predict Unstable Long-Term Remission?

Can Foot Synovitis in RA Help Predict Unstable Long-Term Remission?

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Foot synovitis may predict patients who are at higher risk of unstable RA remission.

Pain Pharmacotherapy Changes For RA During Pregnancy

Pain Pharmacotherapy Changes For RA During Pregnancy

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The pregnant patient with rheumatoid arthritis may need to have pain medication changed due to potential effects on the fetus.

Serotonin Plays Fundamental Role in Rheumatoid Arthritis

Serotonin Plays Fundamental Role in Rheumatoid Arthritis

Serotonin shows it plays a fundamental role in RA through regulation of the Th17/T-regulatory cell balance.

PTSD Symptomatology Associated With Increased Risk of RA

PTSD Symptomatology Associated With Increased Risk of RA

In prospective cohort study of women, elevated risk for rheumatoid arthritis is independent of smoking.

Can Green Tea Alleviate Rheumatoid Arthritis Symptoms?

Can Green Tea Alleviate Rheumatoid Arthritis Symptoms?

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A molecule found in green tea may block a protein that causes the symptoms of rheumatoid arthritis.

Lower Rheumatoid Arthritis Activity Seen at Practices with NPs, PAs

Lower Rheumatoid Arthritis Activity Seen at Practices with NPs, PAs

Patients seen in practices with NPs or PAs had lower RA disease activity over 2 years compared to those seen in rheumatologist-only practices.

Is Treat-To-Target More Effective for Rheumatoid Arthritis?

Is Treat-To-Target More Effective for Rheumatoid Arthritis?

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The likelihood of achieving remission based on ACR/EULAR criteria was 52% higher when a treat-to-target strategy was followed.

Rheumatoid Arthritis Linked to Neuropsychiatric Symptoms

Rheumatoid Arthritis Linked to Neuropsychiatric Symptoms

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Review examines neuropsychiatric manifestations associated with rheumatoid arthritis.

AMSSM Recommends Viscosupplementation for Knee Osteoarthritis

AMSSM Recommends Viscosupplementation for Knee Osteoarthritis

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Patients treated with viscosupplementation had a 15% and 11% greater chance of achieving OARSI responder status than did those treated with intra-articular corticosteroids and placebo, respectively.

Low-Impact Exercise Can Benefit Arthritis Symptoms

Low-Impact Exercise Can Benefit Arthritis Symptoms

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After engaging in an exercise program, participants' muscle and joint pain decreased by a significant 32%.

Accurately Diagnosing Fibromyalgia

Accurately Diagnosing Fibromyalgia

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Recent questionnaires reveal differences in patient experiences with fibromyalgia.

Do Patients With Rheumatoid Arthritis Benefit From Vitamin D Supplements?

Do Patients With Rheumatoid Arthritis Benefit From Vitamin D Supplements?

Improvement in disease activity for patients with vitamin D deficiency at baseline.

Aerobic Exercise May Cut Fatigue in Rheumatoid Arthritis

Aerobic Exercise May Cut Fatigue in Rheumatoid Arthritis

While positive effects were seen, they were small and not statistically significant at 24 weeks.

Weekly Leflunomide Could Be Effective For Early Rheumatoid Arthritis

Weekly Leflunomide Could Be Effective For Early Rheumatoid Arthritis

Similar benefits seen with weekly 50 mg dose versus daily 10 mg dose.

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