Pregabalin

Pregabalin Monotherapy Superior to Opioids With or Without Pregabalin in Patients With Fibromyalgia

Pregabalin Monotherapy Superior to Opioids With or Without Pregabalin in Patients With Fibromyalgia

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The use of pregabalin alone vs pregabalin plus opioids or opioids alone may result in more favorable outcomes in terms of pain interference and pain severity in patients with fibromyalgia.

Hand Osteoarthritis Pain Alleviated With Pregabalin

Hand Osteoarthritis Pain Alleviated With Pregabalin

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Pregabalin, but not duloxetine, was shown to improve pain and function scores in patients with hand osteoarthritis.

FDA Approves New Treatment for Diabetic Peripheral Neuropathy, Postherpetic Neuralgia

FDA Approves New Treatment for Diabetic Peripheral Neuropathy, Postherpetic Neuralgia

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The FDA has approved Lyrica CR, a once-daily treatment for the management of neuropathic pain associated with diabetic peripheral neuropathy and the management of postherpetic neuralgia.

Restless Leg Syndrome Responsiveness to Rotigotine, Gabapentin Enacarbil, and Pregabalin

Restless Leg Syndrome Responsiveness to Rotigotine, Gabapentin Enacarbil, and Pregabalin

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The dopaminergic medication rotigotine and the α-2-δ ligands gabapentin enacarbil and pregabalin provide similar treatment effects for patients with restless leg syndrome.

Gabapentinoids: Evaluating the Benefits for Chronic Low Back Pain

Gabapentinoids: Evaluating the Benefits for Chronic Low Back Pain

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Gabapentinoid use presents significant risk for adverse events and provides few benefits for patients with chronic low back pain.

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

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The use of gabapentin, pregabalin, or both is effective for reducing pruritus and neuropathic pain in burn survivors.

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

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Patients with neuropathic pain are more likely to achieve effective therapeutic dose when treated with pregabalin compared with gabapentin.

Nighttime Opioid Combination to Treat Fibromyalgia With PTSD

Nighttime Opioid Combination to Treat Fibromyalgia With PTSD

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In patients with concomitant fibromyalgia and PTSD, opioid therapy was shown to improve quality of life and help patients return to a greater sense of "normalcy."

Diabetic Peripheral Neuropathic Pain: Evaluating Treatment Options

Diabetic Peripheral Neuropathic Pain: Evaluating Treatment Options

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Dr Cuevas-Trisan covered the evaluation and management of diabetic peripheral neuropathic pain during his presentation at PAINWeek 2017.

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

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Preemptive analgesia seeks to prevent central sensitization and ensuing chronic pain, a concept that has shown promising results in preliminary studies.

Gabapentinoids: Are They Overprescribed?

Gabapentinoids: Are They Overprescribed?

Clinicians may be overprescribing gabapentinoids, in part as a response to the opioid epidemic, and prescribing them for almost any type of pain.

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Patients with neuropathic pain who do not respond to a low dose of pregabalin can benefit from a higher dose.

Response to Pregabalin for Fibromyalgia-Related Pain in Patients Taking Antidepressants

Response to Pregabalin for Fibromyalgia-Related Pain in Patients Taking Antidepressants

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Researchers identified characteristics associated with pain improvement in patients with fibromyalgia who take antidepressant medications.

Trigeminal Neuralgia: Assessing Treatment Patterns to Improve Outcomes

Trigeminal Neuralgia: Assessing Treatment Patterns to Improve Outcomes

In a 3-year period, 45% of patients with trigeminal neuralgia received at least 3 unique treatments.

Pregabalin Not Effective for Sciatica Treatment

Pregabalin Not Effective for Sciatica Treatment

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A randomized trial found that pregabalin is not more effective than placebo in treating sciatica, and resulted in more adverse effects.

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

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A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.

Drugs Effective on Diabetic Peripheral Neuropathy-Related Pain

Drugs Effective on Diabetic Peripheral Neuropathy-Related Pain

Several classes of drugs reduce neuropathy-related pain better than placebo.

Pregabalin for Sciatica: Is It Effective?

Pregabalin for Sciatica: Is It Effective?

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In patients with sciatica pain, treatment with pregabalin did not significantly reduce pain intensity compared with placebo.

Assessing Pregabalin Efficacy With Concomitant Neuropathic Pain Medications

Assessing Pregabalin Efficacy With Concomitant Neuropathic Pain Medications

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The therapeutic efficacy of pregabalin in treating 2 types neuropathic pain (NeP) is not influenced by concomitant NeP medications.

An Overview of Diabetic Peripheral Neuropathy

An Overview of Diabetic Peripheral Neuropathy

Symptoms of diabetic peripheral neuropathy include lower-extremity weakness, in addition to tingling, pain and burning.

Costs of Pregabalin vs Gabapentin for Peripheral Neuropathic Pain

Costs of Pregabalin vs Gabapentin for Peripheral Neuropathic Pain

Lower cost for pregabalin Tx due to lower use of concomitant medications, fewer primary care visits, and fewer days of sick leave.

Pregabalin Also Effective for Established Neuropathic Pain

Pregabalin Also Effective for Established Neuropathic Pain

In all patients together, pregabalin significantly improved pain score at end point versus placebo; similar results were seen in each pain duration category.

Gabapentin Abuse in Patients on Opioid Pain Medications

Gabapentin Abuse in Patients on Opioid Pain Medications

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A surprising number of patients already prescribed opioids were found to be abusing gabapentin.

Functional Improvements Related to Neuropathic Pain Relief in SCI Patients

Functional Improvements Related to Neuropathic Pain Relief in SCI Patients

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Pregabalin was associated with shifts toward greater pain relief and improved function compared to placebo.

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