Postsurgical Pain

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

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Compared with placebo, gabapentin administered pre- and postoperatively may reduce the time to postoperative opioid cessation, but was not shown to improve postoperative pain resolution.

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

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The use of statins after hip surgery may not reduce pain levels or the need for opioids.

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Genetics may be a factor in the experience of chronic postoperative pain as 42 polymorphisms were found to be correlated with chronic postsurgical pain.

Opioid Prescribing vs Consumption Following Rhinoplasty

Opioid Prescribing vs Consumption Following Rhinoplasty

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Patients used only 40% of the hydrocodone-acetaminophen combination tablets prescribed to them following rhinoplasty.

Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

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A Surgical Pleth Index target level lower than that reported in the current literature may be more appropriate in research studies examining SPI-guided anesthesia in pediatric patients.

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

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Intraoperative low-dose naloxone reduced postoperative hyperalgesia but had no effect on pain when combined with high-dose remifentanil for elective thyroid surgery.

Postoperative Pain Management in Children: Evidence on Efficacy

Postoperative Pain Management in Children: Evidence on Efficacy

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Fewer randomized controlled trials include children vs adult cohorts, and the evidence pertaining to this population.

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

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Continuous infusions of midazolam plus morphine do not provide additional pain relief compared with intermittent dosing of those drugs, and may increase hospital length of stay among pediatric patients who have undergone cardiac surgery.

Patients' Expectations of Postoperative Pain vs Actual Pain

Patients' Expectations of Postoperative Pain vs Actual Pain

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Patients receiving regional anesthesia are unable to accurately predict pain outcomes after surgery.

Opioid Prescriptions Following Common Surgeries: Optimal Durations

Opioid Prescriptions Following Common Surgeries: Optimal Durations

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Optimal opioid prescription durations following surgical procedures were shown to vary from 4 to 15 days, depending on the type of surgical procedure.

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

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In addition to preoperative femoral nerve block, the use of intra-articular anesthetic injections during arthroscopic hip surgery may offer effective post-procedural pain relief and be associated with a reduced risk for postoperative falls.

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

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Thoracic epidural analgesia is associated with greater pain control, lower need for narcotics, and fewer complications after hepatopancreatobiliary surgery compared with intravenous patient-controlled analgesia.

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

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The use of capsaicin 8% patch repeat treatment is well tolerated and may provide effective long-term benefit in patients with peripheral neuropathic pain.

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

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Preemptive analgesia seeks to prevent central sensitization and ensuing chronic pain, a concept that has shown promising results in preliminary studies.

Sciatic Plus Femoral Nerve Blocks Effective on Total Hip Arthroplasty-Related Pain

Sciatic Plus Femoral Nerve Blocks Effective on Total Hip Arthroplasty-Related Pain

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Adding a sciatic nerve block to a continuous femoral nerve block after total hip arthroplasty significantly reduces pain.

Current State of Evidence on Ketamine: Uses, Effects, Research

Current State of Evidence on Ketamine: Uses, Effects, Research

Ketamine was found to alleviate several pain modalities, and a number of clinical trials investigating its efficacy are ongoing.

Acute Pain Management in the Emergency Department With SoluMatrix Indomethacin

Acute Pain Management in the Emergency Department With SoluMatrix Indomethacin

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SoluMatrix indomethacin may represent a treatment option for the management of moderate acute pain, including patients in emergency room settings.

Opioid Use Before TKA Associated With Worse Pain After Surgery

Opioid Use Before TKA Associated With Worse Pain After Surgery

Patients taking opioids before total knee arthroplasty may have greater pain after the procedure.

Auricular Point Acupressure Reduces Axial Neck Pain

Auricular Point Acupressure Reduces Axial Neck Pain

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Auricular point acupressure may help relieve axial neck pain in patients who have undergone anterior cervical discectomy and fusion.

Sciatic Nerve Block Plus Femoral Nerve Block May Provide Superior Pain Relief After Total Knee Arthroplasty

Sciatic Nerve Block Plus Femoral Nerve Block May Provide Superior Pain Relief After Total Knee Arthroplasty

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The meta-analysis indicated that sciatic plus femoral nerve blocks provide analgesia superior to local infiltration combined with femoral nerve block at 24 and 48 hours following TKA.

Perioperative Lidocaine Offers No Benefits in Patients Undergoing Spinal Fusion

Perioperative Lidocaine Offers No Benefits in Patients Undergoing Spinal Fusion

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Perioperative lidocaine does not reduce morphine use in the first 24 hours after posterior arthrodesis and offers no measurable benefits.

Increased Rates of New Persistent Opioid Use After Minor and Major Surgery

Increased Rates of New Persistent Opioid Use After Minor and Major Surgery

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Elevated rates of new persistent opioid use were found in patients undergoing both minor and major surgical procedures.

Patient-Centered Perioperative Care and Acute Pain Management

Patient-Centered Perioperative Care and Acute Pain Management

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Perioperative surgical homes and Enhanced Recovery After Surgery protocols can improve postoperative outcomes in patients with chronic opioid use.

Sleep Quality Linked With Postoperative Pain Intensity In Children

Sleep Quality Linked With Postoperative Pain Intensity In Children

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An association was found between sleep quality and next-day pain intensity in children undergoing major surgery.

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

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Viewing photographs can decrease pain intensity in patients with chronic pain.

Lidocaine Safe, Effective for Pain in the ICU

Lidocaine Safe, Effective for Pain in the ICU

Intravenous lidocaine seems safe for reducing pain among patients in the intensive care unit with varying degrees of organ dysfunction.

Bupivacaine for Breast Reconstruction-Associated Pain?

Bupivacaine for Breast Reconstruction-Associated Pain?

For patients undergoing autologous breast reconstruction, the incidence of chronic postsurgical pain does not differ for patients receiving transversus abdominis plane catheters delivering bupivacaine or saline bolus.

Three Upcoming Pain Drugs

Three Upcoming Pain Drugs

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Pharmaceutical companies are working to develop non-opioid drugs for chronic and postoperative pain.

COX-2 Inhibition to Reduce Persistent Pain After Breast Cancer Surgery?

COX-2 Inhibition to Reduce Persistent Pain After Breast Cancer Surgery?

COX-2 inhibition in the perioperative period does not further reduce persistent pain after breast cancer surgery.

Intra-Articular Magnesium for Arthroscopic Surgery-Related Pain

Intra-Articular Magnesium for Arthroscopic Surgery-Related Pain

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Results of the meta-analysis indicated that single-dose IA injection of Mg following arthroscopic knee surgery provided effective pain relief, with adverse effects no greater than those seen with placebo.

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