Postoperative Pain

Perioperative Lidocaine May Reduce Risk for Chronic Postsurgical Pain

Perioperative Lidocaine May Reduce Risk for Chronic Postsurgical Pain

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Perioperative lidocaine infusions may reduce the likelihood of developing chronic postsurgical pain.

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

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Adverse events associated with opioids administered for the management of postsurgical and postendoscopy pain may be associated with worse cost and patient outcomes.

Patient-Controlled Analgesia Pumps Have Low Device-Related Error Rates

Patient-Controlled Analgesia Pumps Have Low Device-Related Error Rates

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The management of postsurgical pain with patient-controlled analgesia pumps may be safe, as indicated by a low rate of device-related error.

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

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In this multicenter, double-blind, placebo-controlled trial, patients (N=409) were randomized 1:1:1 to a postoperative regimen of IV tramadol 50mg, IV tramadol 25mg, or placebo administered over 15 minutes at hours 0, 2, 4, and once every 4 hours thereafter (up to 13 doses).

Opioid Use After Elective Surgery Quantified

Opioid Use After Elective Surgery Quantified

Researchers conducted a prospective survey of patients to investigate postoperative opioid use.

Eight Factors Predict Pain After Spine Surgery

Eight Factors Predict Pain After Spine Surgery

An elastic net algorithm was used to create a predictive model of postoperative pain in the first 24 hours after surgery using a randomly selected training cohort.

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

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Postoperative pain management that combines a reduction of opioids with the use of intravenous acetaminophen may shorten hospital length of stay, reduce the rate of complications related to opioids, and lower related costs.

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Additionally, statistical significance vs placebo was also achieved in total postsurgical opioid consumption through 48 hours (P<0.0001); opioid-free subjects through 48 hours (P<0.01); and time to first opioid rescue through 48 hours (P<0.0001).

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

Pre-Op Chronic Opioid Use Ups Poor Outcomes Post Spinal Fusion

Preoperative chronic opioid use is associated with poor outcomes and continued dependence after posterior lumbar fusion.

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

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Multimodal analgesia after hip or knee arthroplasty may be associated with fewer complications and reduced opioid prescriptions and hospital length of stay, compared with unimodal analgesia.

Conventional vs High-Frequency Spinal Cord Stimulation for Chronic Pain

Conventional vs High-Frequency Spinal Cord Stimulation for Chronic Pain

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In a preliminary study, high-frequency spinal cord stimulation was found to be more effective in treating chronic pain than conventional stimulation.

Reducing Opioid Consumption After Scoliosis Surgery in Adolescents

Reducing Opioid Consumption After Scoliosis Surgery in Adolescents

Intravenous acetaminophen with or without ketorolac is associated with reduced opioid consumption and cost of care after scoliosis surgery in adolescents.

Ilioinguinal-Transversus Abdominis Plane Block When Standard Analgesia Fails After Cesarean Delivery

Ilioinguinal-Transversus Abdominis Plane Block When Standard Analgesia Fails After Cesarean Delivery

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Ilioinguinal-transversus abdominis plane block was shown to provide superior pain relief compared with a multimodal analgesic regimen in patients undergoing an elective cesarean delivery.

Guidelines on the Perioperative Pain Management of Patients on Buprenorphine Therapy

Guidelines on the Perioperative Pain Management of Patients on Buprenorphine Therapy

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Clinical best practice recommendations for the use of buprenorphine in the perioperative management of patients undergoing interventional pain procedures and other surgeries were recently published.

Predicting Acute Pain After Cesarean Delivery to Reduce Risk for Persistent Pain

Predicting Acute Pain After Cesarean Delivery to Reduce Risk for Persistent Pain

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The most promising tools to predict acute pain after cesarean delivery are local anesthetic infiltration before placement of spinal anesthesia, and asking patients simple questions about anticipated pain and analgesic needs.

FDA Accepts New Drug Application for Postoperative Ocular Pain, Inflammation

FDA Accepts New Drug Application for Postoperative Ocular Pain, Inflammation

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The FDA has accepted a New Drug Application for an investigational topical twice-a-day product for the treatment of inflammation and pain in patients who have undergone ocular surgery.

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

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Postoperative management of adolescents undergoing posterior spinal fusion surgery with intravenous acetaminophen may have an opioid-sparing effect, due to a reduced hospital length of stay.

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Genetics may be a factor in the experience of chronic postoperative pain as 42 polymorphisms were found to be correlated with chronic postsurgical pain.

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative levels of serum total cholesterol do not correlate with postoperative pain following laparoscopic surgery for gastric cancer.

Postoperative Pain Management in Children With Developmental Delay

Postoperative Pain Management in Children With Developmental Delay

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Parent- and nurse-controlled analgesia may not reduce postoperative pain in children with developmental delay compared with opioids administered by a nurse as needed.

Smoking Cessation May Increase Postoperative Opioid Use

Smoking Cessation May Increase Postoperative Opioid Use

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Abstinent smokers may have reduced preoperative pain tolerance and increased postoperative opioid use compared with nonsmokers.

Fast Track Designation Granted for Post-Surgical Pain Medication

Fast Track Designation Granted for Post-Surgical Pain Medication

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The FDA has granted Fast Track Designation to the investigational treatment CA-008 (Concentric Analgesics) for the treatment of post-surgical pain.

Systematic Review Does Not Identify Patient-Related Risk Factors for Chronic Pain After Total Knee Replacement Surgery

Systematic Review Does Not Identify Patient-Related Risk Factors for Chronic Pain After Total Knee Replacement Surgery

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There is little evidence to suggest that postoperative knee pain, knee function, or various psychosocial factors influence long-term chronic pain following total knee replacement.

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

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Esmolol was shown to reduce the use of opioids during and after surgery without having a significant impact on postoperative pain scores.

Predictors of Nausea, Vomiting in Patients Receiving Postoperative Opioids

Predictors of Nausea, Vomiting in Patients Receiving Postoperative Opioids

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Opioid treatment of acute postoperative pain was shown to cause high rates of postoperative nausea and vomiting, particularly in women and younger patients.

Increased Rates of New Persistent Opioid Use After Minor and Major Surgery

Increased Rates of New Persistent Opioid Use After Minor and Major Surgery

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Elevated rates of new persistent opioid use were found in patients undergoing both minor and major surgical procedures.

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

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A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.

AAOS: Few Hip Fracture Patients Consistently Take Vitamin D

AAOS: Few Hip Fracture Patients Consistently Take Vitamin D

There was a correlation for consistent vitamin D supplementation with increase in physical component of the SF-12 score.

Sleep Quality Linked With Postoperative Pain Intensity In Children

Sleep Quality Linked With Postoperative Pain Intensity In Children

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An association was found between sleep quality and next-day pain intensity in children undergoing major surgery.

Benchmarking to Address Total Hip Arthroplasty-Related Pain?

Benchmarking to Address Total Hip Arthroplasty-Related Pain?

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A standardized process for data analysis and internal benchmarking facilitated a reduction in pain following hip arthroplasty.

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