Post-Surgical Pain

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Phantom Knee Pain

Phantom Knee Pain

Suspecting that this phenomenon might be the source of my nighttime pain, causing significant REM sleep deprivation, I reasoned that a neuromodulator such as a gabapentinoid might be helpful.

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Efficacy of IV Meloxicam for Bunionectomy-Associated Pain

Efficacy of IV Meloxicam for Bunionectomy-Associated Pain

A once-daily intravenous injection of meloxicam may safely and effectively relieve moderate to severe bunionectomy-associated pain.

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

Opioid-Related Adverse Drug Events Associated With Worse Patient, Cost Outcomes

Adverse events associated with opioids administered for the management of postsurgical and postendoscopy pain may be associated with worse cost and patient outcomes.

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

In this multicenter, double-blind, placebo-controlled trial, patients (N=409) were randomized 1:1:1 to a postoperative regimen of IV tramadol 50mg, IV tramadol 25mg, or placebo administered over 15 minutes at hours 0, 2, 4, and once every 4 hours thereafter (up to 13 doses).

Patient-Controlled Analgesia Pumps Have Low Device-Related Error Rates

Patient-Controlled Analgesia Pumps Have Low Device-Related Error Rates

The management of postsurgical pain with patient-controlled analgesia pumps may be safe, as indicated by a low rate of device-related error.

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

The researchers found that the median prescription size was 350 mg oral morphine equivalents and median patient use was 225 mg oral morphine equivalents following open hiatal hernia repair.

Evaluating Analgesic Benefits of NSAID Combinations for Acute Postoperative Dental Pain

Evaluating Analgesic Benefits of NSAID Combinations for Acute Postoperative Dental Pain

Acetaminophen in combination with ibuprofen or oxycodone, as well as diclofenac, and flurbiprofen may offer more effective analgesia for acute postoperative dental pain in adults.

Opioid Use After Elective Surgery Quantified

Opioid Use After Elective Surgery Quantified

Researchers conducted a prospective survey of patients to investigate postoperative opioid use.

Eight Factors Predict Pain After Spine Surgery

Eight Factors Predict Pain After Spine Surgery

An elastic net algorithm was used to create a predictive model of postoperative pain in the first 24 hours after surgery using a randomly selected training cohort.

Opioids, Sedatives, and the Risk for Cardiopulmonary and Respiratory Arrest

Opioids, Sedatives, and the Risk for Cardiopulmonary and Respiratory Arrest

Opioids and sedatives may represent independent and additive predictors of cardiopulmonary and respiratory arrest in both medical and surgical patients.

Intraoperative Opioid Doses and Rates of Hospital Readmission

Intraoperative Opioid Doses and Rates of Hospital Readmission

The use of high doses of opioids — particularly long-acting opioids — during surgery may increase the risk for 30-day readmission.

Mechanical Plus Chemical Adhesiolysis During Epiduroscopy After Failed Spine Surgery

Mechanical Plus Chemical Adhesiolysis During Epiduroscopy After Failed Spine Surgery

Administration of hyaluronidase and corticosteroid methylprednisolone acetate to the epidural space during epiduroscopy for failed back surgery-related radicular pain may improve back pain and disability at 1 year.

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

Widespread Impact of Reducing Opioids, Adding IV Acetaminophen for Postsurgical Pain Management

Postoperative pain management that combines a reduction of opioids with the use of intravenous acetaminophen may shorten hospital length of stay, reduce the rate of complications related to opioids, and lower related costs.

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Exparel Approved for Use as Interscalene Brachial Plexus Nerve Block

Additionally, statistical significance vs placebo was also achieved in total postsurgical opioid consumption through 48 hours (P<0.0001); opioid-free subjects through 48 hours (P<0.01); and time to first opioid rescue through 48 hours (P<0.0001).

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

Multimodal Analgesia After Knee, Hip Arthroplasty and Perioperative Outcomes

Multimodal analgesia after hip or knee arthroplasty may be associated with fewer complications and reduced opioid prescriptions and hospital length of stay, compared with unimodal analgesia.

Multimodal Analgesia Cuts Complications Post Arthroplasty

Multimodal Analgesia Cuts Complications Post Arthroplasty

Fewer respiratory, GI issues; reductions also seen in opioid prescriptions and hospital length of stay

Prediction Model Shows Accuracy in Estimating Outcomes After Low Back Surgery

Prediction Model Shows Accuracy in Estimating Outcomes After Low Back Surgery

A multivariable prediction model for outcome after lower back surgery may reliably predict 12-month improvements.

Conventional vs High-Frequency Spinal Cord Stimulation for Chronic Pain

Conventional vs High-Frequency Spinal Cord Stimulation for Chronic Pain

In a preliminary study, high-frequency spinal cord stimulation was found to be more effective in treating chronic pain than conventional stimulation.

Reducing Opioid Consumption After Scoliosis Surgery in Adolescents

Reducing Opioid Consumption After Scoliosis Surgery in Adolescents

Intravenous acetaminophen with or without ketorolac is associated with reduced opioid consumption and cost of care after scoliosis surgery in adolescents.

Clinical Pain Assessment Tools May Not Be Useful in Sedated Patients in the ICU

Clinical Pain Assessment Tools May Not Be Useful in Sedated Patients in the ICU

The Critical-Care Pain Observation Tool and the Behavioral Pain Scale may not be optimal tools to assess pain levels in agitated or sedated patients in intensive care units.

Reverse Total Shoulder Arthroplasty: Long-Term Clinical, Subjective Outcomes

Reverse Total Shoulder Arthroplasty: Long-Term Clinical, Subjective Outcomes

Reverse total shoulder arthroplasty in patients with irreparable rotator cuff tear may lead to long-term improvements in range of motion and pain levels, but may be associated with high rates of complications.

No Added Benefit for Acupuncture in Routine Rehabilitation After Total Knee Replacement

No Added Benefit for Acupuncture in Routine Rehabilitation After Total Knee Replacement

The addition of adjunctive acupuncture to routine rehabilitation therapy after total knee replacement may not provide a significant benefit over exercise only for relieving postoperative pain.

Handover of Intraoperative Anesthesia Care Linked to Increase in Adverse Postoperative Outcomes

Handover of Intraoperative Anesthesia Care Linked to Increase in Adverse Postoperative Outcomes

Complete handover of intraoperative anesthesia care is associated with an increased risk of adverse postoperative outcomes among adults undergoing major surgery.

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Perioperative Gabapentin May Modestly Promote Postoperative Opioid Cessation

Compared with placebo, gabapentin administered pre- and postoperatively may reduce the time to postoperative opioid cessation, but was not shown to improve postoperative pain resolution.

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

Intravenous Acetaminophen May Reduce Hospital Length of Stay in Adolescents Undergoing Posterior Spinal Fusion

Postoperative management of adolescents undergoing posterior spinal fusion surgery with intravenous acetaminophen may have an opioid-sparing effect, due to a reduced hospital length of stay.

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

Statins Ineffective in Reducing Pain, Opioid Consumption After Hip Surgery

The use of statins after hip surgery may not reduce pain levels or the need for opioids.

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Chronic Postoperative Pain Risk Linked to Gene Polymorphisms

Genetics may be a factor in the experience of chronic postoperative pain as 42 polymorphisms were found to be correlated with chronic postsurgical pain.

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative Cholesterol Levels Not Linked With Laparoscopic Postoperative Pain

Preoperative levels of serum total cholesterol do not correlate with postoperative pain following laparoscopic surgery for gastric cancer.

Opioid Prescribing vs Consumption Following Rhinoplasty

Opioid Prescribing vs Consumption Following Rhinoplasty

Patients used only 40% of the hydrocodone-acetaminophen combination tablets prescribed to them following rhinoplasty.

Postoperative Pain Management in Children With Developmental Delay

Postoperative Pain Management in Children With Developmental Delay

Parent- and nurse-controlled analgesia may not reduce postoperative pain in children with developmental delay compared with opioids administered by a nurse as needed.

Smoking Cessation May Increase Postoperative Opioid Use

Smoking Cessation May Increase Postoperative Opioid Use

Abstinent smokers may have reduced preoperative pain tolerance and increased postoperative opioid use compared with nonsmokers.