Post-Surgical Pain

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Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

Lower Surgical Pleth Index Target Provides Better Estimate of Pediatric Postsurgical Pain

A Surgical Pleth Index target level lower than that reported in the current literature may be more appropriate in research studies examining SPI-guided anesthesia in pediatric patients.

Opioid Prescribing Suboptimal in Setting of Enhanced Recovery After Surgery

Opioid Prescribing Suboptimal in Setting of Enhanced Recovery After Surgery

Implementation of an enhanced recovery after surgery protocol resulted in an increase in opioid-free anesthesia and multimodal analgesia, but did not modify opioid prescribing practices.

New Drug Application Submitted for Olinvo to Treat Acute Pain

New Drug Application Submitted for Olinvo to Treat Acute Pain

Trevena has submitted their New Drug Application to the FDA for Olinvo, an oliceridine injection, for the management of moderate-to-severe pain in the hospital and similar settings.

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative Naloxone Reduces Remafentanil-Induced Postoperative Hyperalgesia

Intraoperative low-dose naloxone reduced postoperative hyperalgesia but had no effect on pain when combined with high-dose remifentanil for elective thyroid surgery.

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

Midazolam Plus Morphine: Continuous vs Intermittent Infusions for Pediatric Postsurgical Pain

Continuous infusions of midazolam plus morphine do not provide additional pain relief compared with intermittent dosing of those drugs, and may increase hospital length of stay among pediatric patients who have undergone cardiac surgery.

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

Intraoperative Esmolol Decreases Intraoperative, Postoperative Opioid Use

Esmolol was shown to reduce the use of opioids during and after surgery without having a significant impact on postoperative pain scores.

Ibuprofen Comparable With Morphine for Postoperative Pain in Children

Ibuprofen Comparable With Morphine for Postoperative Pain in Children

Among children who have undergone minor outpatient orthopedic surgery, ibuprofen provides equivalent postoperative pain relief compared with oral morphine.

Liposomal Bupivacaine Effective for Shoulder Arthroplasty-Related Pain

Liposomal Bupivacaine Effective for Shoulder Arthroplasty-Related Pain

Among patients undergoing shoulder arthroplasty, liposomal bupivacaine was shown to provide better pain relief at 19 to 21 weeks post-surgery with fewer complications compared with continuous interscalene nerve block.

Systemic Lidocaine May Be Effective for Postmastectomy Pain

Systemic Lidocaine May Be Effective for Postmastectomy Pain

Intraoperative systemic lidocaine may reduce chronic persistent postmastectomy pain at 6 months after surgery.

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

Intra-Articular Anesthesia Reduces Pain After Arthroscopic Hip Surgery

In addition to preoperative femoral nerve block, the use of intra-articular anesthetic injections during arthroscopic hip surgery may offer effective post-procedural pain relief and be associated with a reduced risk for postoperative falls.

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

Thoracic Epidural Analgesia Effective After Multi-Organ Surgery

Thoracic epidural analgesia is associated with greater pain control, lower need for narcotics, and fewer complications after hepatopancreatobiliary surgery compared with intravenous patient-controlled analgesia.

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

Electrotherapy and acupuncture were both found to reduce and delay opioid consumption after total knee arthroplasty.

Psychological Factors, Not Opioid Use, Linked with Disability After Fracture Surgery

Psychological Factors, Not Opioid Use, Linked with Disability After Fracture Surgery

Post-operative opioid therapy may not be necessary for patients undergoing ankle surgery.

Optimal Pain Management After Total Knee Arthroplasty

Optimal Pain Management After Total Knee Arthroplasty

In patients undergoing total knee arthroplasty, sciatic nerve block plus femoral nerve block was more effective for pain relief than local infiltration analgesia plus femoral nerve block.

Inpatient Rehabilitation Effective After Total Knee Arthroplasty?

Inpatient Rehabilitation Effective After Total Knee Arthroplasty?

Inpatient rehabilitation did not improve mobility among adult patients undergoing uncomplicated total knee arthroplasty at 26 weeks after surgery compared with a home-based monitoring program

Opioid Use Before TKA Associated With Worse Pain After Surgery

Opioid Use Before TKA Associated With Worse Pain After Surgery

Patients taking opioids before total knee arthroplasty may have greater pain after the procedure.

Auricular Point Acupressure Reduces Axial Neck Pain

Auricular Point Acupressure Reduces Axial Neck Pain

Auricular point acupressure may help relieve axial neck pain in patients who have undergone anterior cervical discectomy and fusion.

Sciatic Nerve Block Plus Femoral Nerve Block May Provide Superior Pain Relief After Total Knee Arthroplasty

Sciatic Nerve Block Plus Femoral Nerve Block May Provide Superior Pain Relief After Total Knee Arthroplasty

The meta-analysis indicated that sciatic plus femoral nerve blocks provide analgesia superior to local infiltration combined with femoral nerve block at 24 and 48 hours following TKA.

Perioperative Lidocaine Offers No Benefits in Patients Undergoing Spinal Fusion

Perioperative Lidocaine Offers No Benefits in Patients Undergoing Spinal Fusion

Perioperative lidocaine does not reduce morphine use in the first 24 hours after posterior arthrodesis and offers no measurable benefits.

Pediatric Chronic Postsurgical Pain Prevalence, Risk Factors

Pediatric Chronic Postsurgical Pain Prevalence, Risk Factors

An estimated 20% of children have chronic postsurgical pain 12 months after surgery; several presurgical factors predict CPSP in these patients.

Scheduled Oral Analgesia for Superior Pain Control in Postcesarean Women

Scheduled Oral Analgesia for Superior Pain Control in Postcesarean Women

Prescheduled pain management strategies after cesarean delivery are superior to receiving medications on-demand.

Joint Replacement Surgery Outcomes Improved With SSRIs

Joint Replacement Surgery Outcomes Improved With SSRIs

Selective serotonin reuptake inhibitor use was associated with a reduced risk of revision surgery following total hip or total knee replacement surgery.

Sleep Quality Linked With Postoperative Pain Intensity In Children

Sleep Quality Linked With Postoperative Pain Intensity In Children

An association was found between sleep quality and next-day pain intensity in children undergoing major surgery.

Thoracic Paravertebral Nerve Block for Postthoracotomy Pain

Thoracic Paravertebral Nerve Block for Postthoracotomy Pain

Continuous thoracic paravertebral nerve block is similarly effective as epidural anesthesia for the management of postthoracotomy pain.

Bupivacaine for Breast Reconstruction-Associated Pain?

Bupivacaine for Breast Reconstruction-Associated Pain?

For patients undergoing autologous breast reconstruction, the incidence of chronic postsurgical pain does not differ for patients receiving transversus abdominis plane catheters delivering bupivacaine or saline bolus.

Benchmarking to Address Total Hip Arthroplasty-Related Pain?

Benchmarking to Address Total Hip Arthroplasty-Related Pain?

A standardized process for data analysis and internal benchmarking facilitated a reduction in pain following hip arthroplasty.

Difficulty in Evaluating Pharmacologic Interventions Following Craniotomy

Difficulty in Evaluating Pharmacologic Interventions Following Craniotomy

Studies reporting pharmacological and adjuvant analgesic modalities for post-craniotomy pain control have significant divergence in their research methods.

COX-2 Inhibition to Reduce Persistent Pain After Breast Cancer Surgery?

COX-2 Inhibition to Reduce Persistent Pain After Breast Cancer Surgery?

COX-2 inhibition in the perioperative period does not further reduce persistent pain after breast cancer surgery.

Pain Control After Nephrectomy: Epidural & Continuous Surgical Site Analgesia

Pain Control After Nephrectomy: Epidural & Continuous Surgical Site Analgesia

Many patients experience pain months after nephrectomy. Continuous surgical site analgesia may offer the best long-term pain control.

Intra-Articular Magnesium for Arthroscopic Surgery-Related Pain

Intra-Articular Magnesium for Arthroscopic Surgery-Related Pain

Results of the meta-analysis indicated that single-dose IA injection of Mg following arthroscopic knee surgery provided effective pain relief, with adverse effects no greater than those seen with placebo.

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