Pharmacology

Complementary Approaches to Chronic Pain Management

Complementary Approaches to Chronic Pain Management

Pharmacologic-only approaches to the management of chronic pain seldom provide complete/adequate pain relief and experts advocate for an integrative approach to the management of chronic pain.

A Case Against Completing Antibiotic Course

A Case Against Completing Antibiotic Course

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New evidence suggests that stopping antibiotics sooner is a safe and effective way to reduce antibiotic overuse.

Interchangeability Study Initiated for Adalimumab Biosimilar

Interchangeability Study Initiated for Adalimumab Biosimilar

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Boehringer Ingelheim has initiated a clinical study to investigate the interchangeability between an adalimumab biosimilar candidate and Humira.

Benzodiazepine Dependence: Treatment Options

Benzodiazepine Dependence: Treatment Options

There is good evidence for cognitive behavioral therapy and motivational approaches to dependence.

Off-label Antidepressant Prescriptions Often Unsupported by Strong Evidence

Off-label Antidepressant Prescriptions Often Unsupported by Strong Evidence

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These findings highlight an urgent need to produce more evidence on the risks and benefits of off-label antidepressant use.

Feast or Famine: The World's Opioid Gap

Feast or Famine: The World's Opioid Gap

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Much of the third world is suffering in pain without access to opioids. This imbalance has been called the opioid gap. How can we get opioids to patients who need them?

Could New Screening Tools Help Curb Opioid Misuse in Primary Care?

Could New Screening Tools Help Curb Opioid Misuse in Primary Care?

A recent study published in The Journal of Pain evaluated the effectiveness of a brief self-assessment tool called the Opioid Compliance Checklist in identifying adherence, or misuse, among patients prescribed opioids.

FDA Approves Zurampic (Lesinurad) to Treat High Hyperuricemia Associated With Gout

FDA Approves Zurampic (Lesinurad) to Treat High Hyperuricemia Associated With Gout

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The drug assists the kidney excrete uric acid by impeding the function of transporter proteins involved in uric acid reabsorption in the kidney.

Study: Opioid-Related Constipation Treatment Suboptimal in Pregnancy

Study: Opioid-Related Constipation Treatment Suboptimal in Pregnancy

PAMORA strategy appears to safe with superior effectiveness.

New Insight on the Role of Aspirin in Breast Cancer

New Insight on the Role of Aspirin in Breast Cancer

Two new studies shed more light on whether of aspirin can help treat breast cancer patients.

Pharmacogenetic Testing: A Good Tool for Treating Patients with Pain

Pharmacogenetic Testing: A Good Tool for Treating Patients with Pain

Pharmacogenetic testing yields information that informs how an individual will metabolize medications.

The Impact of Risk Reduction Initiatives on Chronic Opioid Use

The Impact of Risk Reduction Initiatives on Chronic Opioid Use

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Exposing clinicians to a multifaceted risk-reduction initiative significantly shifts prescribing practices away from high-dose chronic opioid therapy.

Which Clinical Trial Design is the Right One?

Which Clinical Trial Design is the Right One?

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The FDA approval process requires 3 elements: efficacy, safety, and ability to manufacture quality product reproducibly.

New Opioid Alternative Promising for Anesthesia, Sedation

New Opioid Alternative Promising for Anesthesia, Sedation

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Isovaline may be a new alternative to opioids for anesthesia and procedural sedation, new data published in Anesthesia & Analgesia has shown.

Pain Treatment Selection: Which is Best?

Pain Treatment Selection: Which is Best?

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Treating painful conditions typically requires an approach that uses a variety of methods.

Study: Medication Review At ICU To Ward Transfer Cuts Drug Problems

Study: Medication Review At ICU To Ward Transfer Cuts Drug Problems

Significant reduction in drug-related problems with immediate communication of recommendations.

CDC: Aspirin Use Common Among Americans With Heart Disease

CDC: Aspirin Use Common Among Americans With Heart Disease

Clinical and community-based approaches should be used to increase aspirin use among low-use groups.

Antidepressant, Painkiller Combination May Raise Risk Of Intracranial Hemorrhage

Antidepressant, Painkiller Combination May Raise Risk Of Intracranial Hemorrhage

No indication any particular type of antidepressant carries a greater risk than others.

Pharmacy Shopping, Overlapping Rx Linked To Opioid Overdoses

Pharmacy Shopping, Overlapping Rx Linked To Opioid Overdoses

Patients who use of multiple pharmacies concurrently (pharmacy shopping) and have overlapping prescriptions for opioid medications have a greater risk of opioid overdose events.

Tricare Rolls Out Screening Program That May Limit Access to Some Pain Killers

Tricare Rolls Out Screening Program That May Limit Access to Some Pain Killers

If a compound does not pass an initial screen, a switch can be requested.

Diabetes Screening at Dentist May Be Effective

Diabetes Screening at Dentist May Be Effective

Researchers find testing blood from mouth is as accurate as finger prick at diagnosing condition

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