Oxycodone

Low Potential for Abuse With Extended-Release Oxycodone

Low Potential for Abuse With Extended-Release Oxycodone

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An abuse liability assessment was conducted to determine the abuse potential and pharmacokinetics of extended-release vs immediate-release oxycodone.

Extended-Release Oxycodone Efficacious for Chronic Low Back Pain

Extended-Release Oxycodone Efficacious for Chronic Low Back Pain

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Abuse-deterrent extended-release oxycodone (Xtampza® ER; Collegium Pharmaceutical) provided adequate pain relief for patients with chronic low back pain who were previously receiving immediate-release oxycodone.

Morphine and Oxycodone Abuse-Deterrent Formulations Lower Absorption Rates

Morphine and Oxycodone Abuse-Deterrent Formulations Lower Absorption Rates

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Administration of abuse-deterrent formulations of immediate-release oxycodone and extended-release morphine leads to slower and lower absorption rates in nondependent recreational drug users compared with standard oxycodone and morphine formulations.

Tramadol Use Associated With Hypoglycemia in Hospitalized Patients

Tramadol Use Associated With Hypoglycemia in Hospitalized Patients

In hospitalized patients, tramadol use was shown to be associated with hypoglycemia.

A Fifth of Bariatric Surgery Patients Using Opioids 7 Years Later

A Fifth of Bariatric Surgery Patients Using Opioids 7 Years Later

About 20% of U.S. bariatric surgery patients are still using prescription opioids 7 years later.

Weight-Loss Drug May Help Curb Opiate Addiction

Weight-Loss Drug May Help Curb Opiate Addiction

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A prescription weight-loss drug reduced the urge to use opiates like oxycodone.

CDC Report on Fatal Drug Overdoses in the US

CDC Report on Fatal Drug Overdoses in the US

Drug overdose deaths have nearly tripled in the United States since 1999, with the largest increases seen for whites and middle-aged Americans.

Certain Chronic Pain Medications May Have Endocrinologic Side Effects

Certain Chronic Pain Medications May Have Endocrinologic Side Effects

Chronic pain patients being treated with certain opioid and non-opioid medications had significantly lower serum concentrations of free testosterone and free estradiol.

Preventing and Managing Neonatal Abstinence Syndrome

Preventing and Managing Neonatal Abstinence Syndrome

The article reviews the epidemiology, clinical features, outcomes, prevention strategies, risk identification and management NAS.

Comparing Oxycodone/Naloxone to Tapentadol for Chronic Low Back Pain

Comparing Oxycodone/Naloxone to Tapentadol for Chronic Low Back Pain

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The benefit-risk profile of oxycodone/naloxone was found to be noninferior compared to tapentadol, and oxycodone/naloxone demonstrated superior analgesic efficacy.

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