Opioids

Neonatal Withdrawal Risk Higher With Opioids Plus Psychotropic Drugs

Neonatal Withdrawal Risk Higher With Opioids Plus Psychotropic Drugs

By

The infants of women taking opioids concomitantly with psychotropic medications were found to have a substantially heightened risk of neonatal drug withdrawal.

End-of-Life Care Improved with Appropriate Hospice, Opioid Use

End-of-Life Care Improved with Appropriate Hospice, Opioid Use

Insurance claims and clinical information were linked to examine indicators of high-quality end-of-life care.

Strategies to Curb the Opioid Epidemic: A National Academies Report

Strategies to Curb the Opioid Epidemic: A National Academies Report

By

Highlights from the National Academies of Sciences, Engineering, and Medicine report titled "Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use."

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

By

Once-weekly subcutaneous buprenorphine injections block the euphoric effects of opioids and suppress opioid withdrawal in patients with opioid use disorder.

Opioid Prescription Patterns in Patients With Back Pain and Depression

Opioid Prescription Patterns in Patients With Back Pain and Depression

Patients with low back pain who are depressed are more likely to be prescribed opioids, and to be prescribed higher doses.

New Treatment for Opioid-Induced Constipation

New Treatment for Opioid-Induced Constipation

By

Naldemedine, a recently approved agent for opioid-induced constipation, showed good safety and significantly higher responder rates than placebo in a couple of 12-week, international, randomized trials.

Opioid Use Before TKA Associated With Worse Pain After Surgery

Opioid Use Before TKA Associated With Worse Pain After Surgery

Patients taking opioids before total knee arthroplasty may have greater pain after the procedure.

Magnesium for Patients on Opioids for Pain

Magnesium for Patients on Opioids for Pain

Opioid tolerance may be curbed by taking magnesium.

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

By

A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.

Is Opioid-Induced Hyperalgesia Lessened by Switching to Buprenorphine?

Is Opioid-Induced Hyperalgesia Lessened by Switching to Buprenorphine?

By

Changes in several measures of pain in patients suspected of opioid-induced hyperalgesia were observed after transitioning from opioids to buprenorphine.

Teens Exposed to Prescription Opioids at Risk for Serious Outcomes

Teens Exposed to Prescription Opioids at Risk for Serious Outcomes

Teenagers with prescription opioid exposures are more likely to have health care facility admission and serious medical outcomes than younger children.

CDC Guideline on Prescribing Opioids: Some Major Concerns

CDC Guideline on Prescribing Opioids: Some Major Concerns

By

Dr Fudin discusses concerns he has regarding the CDC guideline for prescribing opioids for chronic pain.

Psychosocial Factors Predict Analgesic Response to Morphine

Psychosocial Factors Predict Analgesic Response to Morphine

By

Psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain.

Sublingual Fentanyl Preferred, But Less Effective Than Subcutaneous Morphine

Sublingual Fentanyl Preferred, But Less Effective Than Subcutaneous Morphine

By

Fentanyl sublingual tablets are preferred over subcutaneous morphine in patients with severe breakthrough cancer pain.

Preventing and Managing Neonatal Abstinence Syndrome

Preventing and Managing Neonatal Abstinence Syndrome

The article reviews the epidemiology, clinical features, outcomes, prevention strategies, risk identification and management NAS.

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

By

Rapid increases in prescription opioid dose may lead to higher rates of new-onset depression.

Assessment of Single-Entity Hydrocodone's Otological Safety

Assessment of Single-Entity Hydrocodone's Otological Safety

By

Many analgesics and analgesic combinations for chronic pain have shown temporary and permanent otological effects, including hearing loss.

Risk of Serotonin Toxicity due to Drug-Drug Interactions for the Treatment of Migraines

Risk of Serotonin Toxicity due to Drug-Drug Interactions for the Treatment of Migraines

By

Detailed examination of a patient's active medication critically important.

Reduced Opioid Requirements When Comorbid OA, Hypertension Treated With Beta-Blockers

Reduced Opioid Requirements When Comorbid OA, Hypertension Treated With Beta-Blockers

By

The anti-nociceptive effect of beta-adrenergic blockade is associated with decreased joint pain and reduced opioid requirements in patients with symptomatic large joint osteoarthritis and hypertension.

Gabapentin Abuse in Patients on Opioid Pain Medications

Gabapentin Abuse in Patients on Opioid Pain Medications

By

A surprising number of patients already prescribed opioids were found to be abusing gabapentin.

Nebulized Fentanyl vs. IV Opioids for Acute Pain

Nebulized Fentanyl vs. IV Opioids for Acute Pain

By

Nebulized fentanyl is as effective as IV opioids for the treatment of acute pain.

New Guideline Issued on Chronic Pain Management in Adult Cancer Patients

New Guideline Issued on Chronic Pain Management in Adult Cancer Patients

By

New guideline addresses cancer-related chronic pain

Opioids Prolonging Hyperalgesia?

Opioids Prolonging Hyperalgesia?

By

Involvement of microglia, inflammation

Opioids: Not an Effective Stand-Alone Treatment for Chronic Pain Following Surgery

Opioids: Not an Effective Stand-Alone Treatment for Chronic Pain Following Surgery

By

Importance of finding ways to mitigate chronic opioid use after surgery.

Recommendations for the Management of Chronic Visceral Pain

Recommendations for the Management of Chronic Visceral Pain

By

Neurobiological mechanisms are distinct from somatic pain

Preoperative Opioid Use Significantly Impacts Postoperative Opioid Course

Preoperative Opioid Use Significantly Impacts Postoperative Opioid Course

By

Preoperative opioid use is a better predictor for prolonged postoperative opioid use than pain, substance abuse, and affective disorder.

FDA Announces Enhanced Warning Labels on Opioid Pain Medications

FDA Announces Enhanced Warning Labels on Opioid Pain Medications

New labeling rules mostly aimed at immediate-release versions of opioids.

Physicians Respond Positively to New CDC Opioid Guidelines

Physicians Respond Positively to New CDC Opioid Guidelines

Mainly supportive of guidelines, but concerns include lack of evidence underlying recommendations.

Are Opioids Linked to Higher Risk of Infections in RA?

Are Opioids Linked to Higher Risk of Infections in RA?

Increased risk of hospitalization for serious infection.

Choosing the Right Risk Assessment Tools to Identify Aberrant Behavior

Choosing the Right Risk Assessment Tools to Identify Aberrant Behavior

Tools vary in how they are administered, the ease of scoring, and the detail of information provided.

Sign Up for Free e-Newsletters