Opioids

Immediate Access to Opioid Agonist Treatment Is Cost-Effective, Beneficial

Immediate Access to Opioid Agonist Treatment Is Cost-Effective, Beneficial

Immediate access to opioid agonist treatment for patients presenting with opioid use disorder may provide greater health benefits at less cost than observed standard of care.

FDA Grants Priority Review to Lofexidine for Management of Opioid Withdrawal Symptoms

FDA Grants Priority Review to Lofexidine for Management of Opioid Withdrawal Symptoms

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US WorldMeds announced that the Food and Drug Administration has accepted for Priority Review the New Drug Application for lofexidine to manage the symptoms associated with opioid withdrawal and to facilitate completion of opioid discontinuation treatment.

Short- vs Long-Acting Opioids for Osteoarthritis Pain

Short- vs Long-Acting Opioids for Osteoarthritis Pain

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In addition to being safer and more cost-effective, short-acting opioids are comparable with long-acting opioids for pain management in patients with chronic osteoarthritis.

Pregabalin Monotherapy Superior to Opioids With or Without Pregabalin in Patients With Fibromyalgia

Pregabalin Monotherapy Superior to Opioids With or Without Pregabalin in Patients With Fibromyalgia

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The use of pregabalin alone vs pregabalin plus opioids or opioids alone may result in more favorable outcomes in terms of pain interference and pain severity in patients with fibromyalgia.

Clinton Foundation's Recommendations to Address the Opioid Crisis

Clinton Foundation's Recommendations to Address the Opioid Crisis

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The Clinton Foundation's Health Matters Initiative, in partnership with the Johns Hopkins Bloomberg School of Public Health, issued a report providing 49 recommendations under 10 topic areas on how to address the opioid crisis.

DEA Announces All Illicit Fentanyl Analogues Will Be Subject to Criminal Prosecution

DEA Announces All Illicit Fentanyl Analogues Will Be Subject to Criminal Prosecution

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The announcement comes from the Department of Justice and will give the Drug Enforcement Agency the ability to take immediate action to stop illicit fentanyl from coming into the US.

Opioid Manufacturers Providing Training for Clinicians

Opioid Manufacturers Providing Training for Clinicians

In an effort to halt the ongoing opioid addiction crisis, US regulators are requiring manufacturers to provide extensive training to doctors.

Motivational Interview Intervention Reduces Opioid Overdose

Motivational Interview Intervention Reduces Opioid Overdose

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A motivational interviewing intervention delivered by trained counselors reduced the rate of opioid overdoses in participants with opioid use disorder.

Illicit Fentanyl Linked to More Than Half of US Overdose Deaths

Illicit Fentanyl Linked to More Than Half of US Overdose Deaths

Fentanyl was detected in more than half of the 5152 opioid overdose deaths in 10 states from July through December of 2016.

FDA: Opioid Addiction Medication Should Not Be Withheld While Taking CNS Depressants

FDA: Opioid Addiction Medication Should Not Be Withheld While Taking CNS Depressants

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A review of several published studies showed that the evidence did not support dose limitations or arbitrary caps of buprenorphine or methadone as a strategy to address benzodiazepine or other CNS depressant use in MAT-treated patients.

Transdermal to Buccal Buprenorphine Transition

Transdermal to Buccal Buprenorphine Transition

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Patients can be transitioned from transdermal to buccal formulations of buprenorphine within 12 hours of patch removal using the recommended buccal formulation titration doses and schedule.

New CDC Communication Campaign Addresses Opioid Epidemic

New CDC Communication Campaign Addresses Opioid Epidemic

The CDC is launching a communication campaign featuring accounts of people recovering from opioid use disorder, and those who have lost someone to opioid overdose, in an effort to fight the prescription overdose epidemic.

Opioid Use Low Among Veterans With Recent Traumatic Brain Injury Diagnosis

Opioid Use Low Among Veterans With Recent Traumatic Brain Injury Diagnosis

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Opioid use was shown to be relatively low in veterans of Iraq and Afghanistan with recently diagnosed traumatic brain injuries, but approximately one-quarter of those who initiated opioids were chronic users.

Survey Finds Teens Divided on Beliefs and Attitudes of Prescription Drug Abuse

Survey Finds Teens Divided on Beliefs and Attitudes of Prescription Drug Abuse

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A survey sought to clarify teens' perceptions of recreational use of prescription drugs.

Diphenhydramine Decreases Pain During Colonoscopy for Chronic Opioid Users

Diphenhydramine Decreases Pain During Colonoscopy for Chronic Opioid Users

For chronic opioid users, diphenhydramine in addition to conventional sedatives decreases pain and improves quality of sedation during colonoscopy.

Opioid Dependence Prevention Treatments Compared

Opioid Dependence Prevention Treatments Compared

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Significantly less heroin cravings were reported in the extended-release naltrexone group and treatment satisfaction was also reported higher in this group compared to the buprenorphine-naloxone group.

Virtual Reality for Pain Relief: Understanding the Underlying Mechanisms

Virtual Reality for Pain Relief: Understanding the Underlying Mechanisms

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Virtual reality technology may relieve pain through neurophysiologic changes related to conditioning and exposure, in addition to mechanisms involving distraction.

Corticosteroids Effective in Total Knee or Hip Arthroplasty-Associated Pain

Corticosteroids Effective in Total Knee or Hip Arthroplasty-Associated Pain

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The use of perioperative intravenous corticosteroids provides effective pain relief, has a favorable safety profile, and is associated with a reduction in opioid use in patients undergoing total knee or hip arthroplasty.

FDA's Strategies for Managing Patients Taking CNS Depressants and Opioids

FDA's Strategies for Managing Patients Taking CNS Depressants and Opioids

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The FDA has recently issued a report advising against the use of buprenorphine and methadone medications in patients taking benzodiazepines and/or other central nervous system depressants.

Stigma Among Individuals Seeking Treatment for Opioid Abuse

Stigma Among Individuals Seeking Treatment for Opioid Abuse

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Self-stigma and perceived stigma were shown to be highest among people with opioid use disorders who have previously entered detoxification programs or who have recently injected drugs.

CVS to Limit Opioids Dispensed to Opioid-Naive Patients to a 7-day Supply

CVS to Limit Opioids Dispensed to Opioid-Naive Patients to a 7-day Supply

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At the pharmacy level, a greater emphasis will be placed on counseling to help patients understand the risks associated with opioid use based on the new Centers for Disease Control and Prevention (CDC) guidelines.

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

Electrotherapy, Acupuncture May Decrease Pain Following Total Knee Arthroplasty

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Electrotherapy and acupuncture were both found to reduce and delay opioid consumption after total knee arthroplasty.

Naloxone Co-Prescribing to Fight Opioid Overdoses: An AMA Recommendation

Naloxone Co-Prescribing to Fight Opioid Overdoses: An AMA Recommendation

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Co-prescribing naloxone with opioids may reduce opioid overdoses while playing a pivotal role in combating the nation's opioid addiction epidemic.

Abuse-Deterrent Opioids Might Not Be the Answer to the Opioid Crisis

Abuse-Deterrent Opioids Might Not Be the Answer to the Opioid Crisis

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Abuse-deterrent opioid formulations may not be the most effective solution to the opioid crisis, according to an editorial published in the New England Journal of Medicine.

Collaborative Care Superior to Standard Care for Opioid Use Disorder

Collaborative Care Superior to Standard Care for Opioid Use Disorder

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Patients with opioid and/or alcohol use disorders have better treatment access and greater rates of alcohol and drug abstinence at 6 months with collaborative care vs standard addiction care.

Long-Term Opioid Rx Use Skyrocketed Between 1999 and 2014

Long-Term Opioid Rx Use Skyrocketed Between 1999 and 2014

Long-term opioid prescription use increased threefold during a 16-year period between 1999 and 2014.

An Overview of Using Naloxone and Opioids for Pain Management

An Overview of Using Naloxone and Opioids for Pain Management

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The increased use of opioid prescriptions to treat chronic pain has resulted in the rise of opioid use disorder, addiction, and abuse. We offer an overview of how and when to prescribe opioids for the management of chronic pain.

Benzodiazepine and Opioid Prescribing in the Elderly: What Are the Risks?

Benzodiazepine and Opioid Prescribing in the Elderly: What Are the Risks?

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Dr Gould covered the risks of co-prescribing benzodiazepines and opioids, particularly for elderly patients, and proposed therapeutic alternatives at PAINWeek 2017.

Overdose: Mitigating the Legal Risk

Overdose: Mitigating the Legal Risk

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Jennifer Bolen, JD, provides PAINWeek 2017 attendees with information on risk reduction and response to medication overdose events.

Motivational Interviewing for Opioid Tapering

Motivational Interviewing for Opioid Tapering

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Behavioral techniques such as motivational interviewing may facilitate the tapering process.

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