Opioids

Magnesium for Patients on Opioids for Pain

Magnesium for Patients on Opioids for Pain

Opioid tolerance may be curbed by taking magnesium.

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

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A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.

Is Opioid-Induced Hyperalgesia Lessened by Switching to Buprenorphine?

Is Opioid-Induced Hyperalgesia Lessened by Switching to Buprenorphine?

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Changes in several measures of pain in patients suspected of opioid-induced hyperalgesia were observed after transitioning from opioids to buprenorphine.

Teens Exposed to Prescription Opioids at Risk for Serious Outcomes

Teens Exposed to Prescription Opioids at Risk for Serious Outcomes

Teenagers with prescription opioid exposures are more likely to have health care facility admission and serious medical outcomes than younger children.

CDC Guideline on Prescribing Opioids: Some Major Concerns

CDC Guideline on Prescribing Opioids: Some Major Concerns

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Dr Fudin discusses concerns he has regarding the CDC guideline for prescribing opioids for chronic pain.

Psychosocial Factors Predict Analgesic Response to Morphine

Psychosocial Factors Predict Analgesic Response to Morphine

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Psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain.

Sublingual Fentanyl Preferred, But Less Effective Than Subcutaneous Morphine

Sublingual Fentanyl Preferred, But Less Effective Than Subcutaneous Morphine

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Fentanyl sublingual tablets are preferred over subcutaneous morphine in patients with severe breakthrough cancer pain.

Preventing and Managing Neonatal Abstinence Syndrome

Preventing and Managing Neonatal Abstinence Syndrome

The article reviews the epidemiology, clinical features, outcomes, prevention strategies, risk identification and management NAS.

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

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Rapid increases in prescription opioid dose may lead to higher rates of new-onset depression.

Assessment of Single-Entity Hydrocodone's Otological Safety

Assessment of Single-Entity Hydrocodone's Otological Safety

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Many analgesics and analgesic combinations for chronic pain have shown temporary and permanent otological effects, including hearing loss.

Risk of Serotonin Toxicity due to Drug-Drug Interactions for the Treatment of Migraines

Risk of Serotonin Toxicity due to Drug-Drug Interactions for the Treatment of Migraines

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Detailed examination of a patient's active medication critically important.

Reduced Opioid Requirements When Comorbid OA, Hypertension Treated With Beta-Blockers

Reduced Opioid Requirements When Comorbid OA, Hypertension Treated With Beta-Blockers

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The anti-nociceptive effect of beta-adrenergic blockade is associated with decreased joint pain and reduced opioid requirements in patients with symptomatic large joint osteoarthritis and hypertension.

Gabapentin Abuse in Patients on Opioid Pain Medications

Gabapentin Abuse in Patients on Opioid Pain Medications

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A surprising number of patients already prescribed opioids were found to be abusing gabapentin.

Nebulized Fentanyl vs. IV Opioids for Acute Pain

Nebulized Fentanyl vs. IV Opioids for Acute Pain

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Nebulized fentanyl is as effective as IV opioids for the treatment of acute pain.

New Guideline Issued on Chronic Pain Management in Adult Cancer Patients

New Guideline Issued on Chronic Pain Management in Adult Cancer Patients

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New guideline addresses cancer-related chronic pain

Opioids Prolonging Hyperalgesia?

Opioids Prolonging Hyperalgesia?

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Involvement of microglia, inflammation

Opioids: Not an Effective Stand-Alone Treatment for Chronic Pain Following Surgery

Opioids: Not an Effective Stand-Alone Treatment for Chronic Pain Following Surgery

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Importance of finding ways to mitigate chronic opioid use after surgery.

Recommendations for the Management of Chronic Visceral Pain

Recommendations for the Management of Chronic Visceral Pain

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Neurobiological mechanisms are distinct from somatic pain

Preoperative Opioid Use Significantly Impacts Postoperative Opioid Course

Preoperative Opioid Use Significantly Impacts Postoperative Opioid Course

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Preoperative opioid use is a better predictor for prolonged postoperative opioid use than pain, substance abuse, and affective disorder.

FDA Announces Enhanced Warning Labels on Opioid Pain Medications

FDA Announces Enhanced Warning Labels on Opioid Pain Medications

New labeling rules mostly aimed at immediate-release versions of opioids.

Physicians Respond Positively to New CDC Opioid Guidelines

Physicians Respond Positively to New CDC Opioid Guidelines

Mainly supportive of guidelines, but concerns include lack of evidence underlying recommendations.

Are Opioids Linked to Higher Risk of Infections in RA?

Are Opioids Linked to Higher Risk of Infections in RA?

Increased risk of hospitalization for serious infection.

Choosing the Right Risk Assessment Tools to Identify Aberrant Behavior

Choosing the Right Risk Assessment Tools to Identify Aberrant Behavior

Tools vary in how they are administered, the ease of scoring, and the detail of information provided.

More than 75% of High School Heroin Users Started With Prescription Opioids

More than 75% of High School Heroin Users Started With Prescription Opioids

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With concerns about opioid prescribing practices on the rise, many are paying closer attention to the increasing usage of heroin, especially among the country's youth

Guidelines for Prescribing Pain Meds for Workers' Compensation

Guidelines for Prescribing Pain Meds for Workers' Compensation

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The top medication classes in workers' compensation are drastically different than group health.

Extended-Release Oxycodone/Acetaminophen: Overview of a Novel Opioid

Extended-Release Oxycodone/Acetaminophen: Overview of a Novel Opioid

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CPA reports on a new analgesic formulation designed to provide both immediate and prolonged analgesia for up to 12 hours in patients with acute pain.

Setting Opioid Dosage Limits in Clinical Practice

Setting Opioid Dosage Limits in Clinical Practice

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Keeping opioid prescribing to 200 mg/d morphine equivalent or less may provide a measure of safety.

Preventing Opioid Abuse: Impact of Tamper-Resistant Formulations

Preventing Opioid Abuse: Impact of Tamper-Resistant Formulations

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Pharmaceutical drug abuse has emerged as a fast-growing global problem that is largely driven by misuse of opioid analgesics.

Opioid Precaution During Cold and Flu Season: Medication Adjustment May Be Required

Opioid Precaution During Cold and Flu Season: Medication Adjustment May Be Required

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A patient with debilitating chronic pain experiences an altered level of consciousness following a bout of the flu. Could his high-dose opioid regimen be to blame?

New Technologies Offer Options for Reducing Opioid Overdoses

New Technologies Offer Options for Reducing Opioid Overdoses

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The pros and cons of intranasal, intramuscular, and autoinjector routes of administration.

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