Patients taking opioids before total knee arthroplasty may have greater pain after the procedure.
Opioid tolerance may be curbed by taking magnesium.
A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.
Changes in several measures of pain in patients suspected of opioid-induced hyperalgesia were observed after transitioning from opioids to buprenorphine.
Teenagers with prescription opioid exposures are more likely to have health care facility admission and serious medical outcomes than younger children.
Dr Fudin discusses concerns he has regarding the CDC guideline for prescribing opioids for chronic pain.
Psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain.
Fentanyl sublingual tablets are preferred over subcutaneous morphine in patients with severe breakthrough cancer pain.
The article reviews the epidemiology, clinical features, outcomes, prevention strategies, risk identification and management NAS.
Rapid increases in prescription opioid dose may lead to higher rates of new-onset depression.
Many analgesics and analgesic combinations for chronic pain have shown temporary and permanent otological effects, including hearing loss.
Detailed examination of a patient's active medication critically important.
The anti-nociceptive effect of beta-adrenergic blockade is associated with decreased joint pain and reduced opioid requirements in patients with symptomatic large joint osteoarthritis and hypertension.
A surprising number of patients already prescribed opioids were found to be abusing gabapentin.
Nebulized fentanyl is as effective as IV opioids for the treatment of acute pain.
New guideline addresses cancer-related chronic pain
Involvement of microglia, inflammation
Importance of finding ways to mitigate chronic opioid use after surgery.
Neurobiological mechanisms are distinct from somatic pain
Preoperative opioid use is a better predictor for prolonged postoperative opioid use than pain, substance abuse, and affective disorder.
New labeling rules mostly aimed at immediate-release versions of opioids.
Mainly supportive of guidelines, but concerns include lack of evidence underlying recommendations.
Increased risk of hospitalization for serious infection.
Tools vary in how they are administered, the ease of scoring, and the detail of information provided.
With concerns about opioid prescribing practices on the rise, many are paying closer attention to the increasing usage of heroin, especially among the country's youth
The top medication classes in workers' compensation are drastically different than group health.
CPA reports on a new analgesic formulation designed to provide both immediate and prolonged analgesia for up to 12 hours in patients with acute pain.
Keeping opioid prescribing to 200 mg/d morphine equivalent or less may provide a measure of safety.
Pharmaceutical drug abuse has emerged as a fast-growing global problem that is largely driven by misuse of opioid analgesics.
A patient with debilitating chronic pain experiences an altered level of consciousness following a bout of the flu. Could his high-dose opioid regimen be to blame?
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