Opioid

Ketamine for Refractory Neuropathic Pain

Ketamine for Refractory Neuropathic Pain

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A ketamine regimen is superior to methadone, or ketamine combined with methadone, in alleviating neuropathic pain and associated sensory changes.

Opioid/Benzodiazepine Combination Increases Risk of Overdose

Opioid/Benzodiazepine Combination Increases Risk of Overdose

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Concurrent benzodiazepine and opioid use increased by 80% between 2001 and 2013 in the United States and significantly contributes to the overall population risk of opioid overdose.

Methadone: Best Practices for Weaning Pediatric Patients

Methadone: Best Practices for Weaning Pediatric Patients

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Practices pertaining to the use of methadone to facilitate opioid weaning in pediatric patients are widely heterogeneous.

Certain Chronic Pain Medications May Have Endocrinologic Side Effects

Certain Chronic Pain Medications May Have Endocrinologic Side Effects

Chronic pain patients being treated with certain opioid and non-opioid medications had significantly lower serum concentrations of free testosterone and free estradiol.

Psychosocial Factors That May Predict Opioid Analgesia

Psychosocial Factors That May Predict Opioid Analgesia

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Multiple psychosocial factors such as depression, anxiety, and pain catastrophizing are associated with opioid analgesic response.

Rates of Opioid Agonist Therapy Prescriptions for Medicare Patients Reflect Treatment Gap

Rates of Opioid Agonist Therapy Prescriptions for Medicare Patients Reflect Treatment Gap

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A small fraction of prescriptions for Medicare patients are for opioid agonist therapy, despite higher rates of abuse.

Mechanisms of Mindfulness Meditation-Induced Analgesia

Mechanisms of Mindfulness Meditation-Induced Analgesia

Common brain regions activated during meditation and pain

Effectiveness of Subdermal Buprenorphine Implants in Maintaining Opioid Abstinence

Effectiveness of Subdermal Buprenorphine Implants in Maintaining Opioid Abstinence

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Buprenorphine implants could help improve relapse prevention in patients who are currently maintaining abstinence with sublingual buprenorphine

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