Opioid Use Disorder

Detox vs Medication-Assisted Treatment for Opioid Use Disorder in Pregnancy: Expert Roundtable

Detox vs Medication-Assisted Treatment for Opioid Use Disorder in Pregnancy: Expert Roundtable

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Based on current evidence, there is a strong consensus that medication-assisted treatment is recommended over detoxification in the treatment of opioid use disorder during pregnancy.

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

Treatment Duration of XR Naltrexone for Opioid Dependence and Outcomes

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A longer duration of extended-release naltrexone treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse.

Intentional Poisoning as a Method for Obtaining Opioid Medications

Intentional Poisoning as a Method for Obtaining Opioid Medications

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According to the authors, this report represents the first case of recurrent fallacious lactatemia secondary to EG poisoning in the setting of drug-seeking behavior.

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

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National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Examining Rates of Long-Term Opioid Use in Youth With Psychiatric Disorders

Examining Rates of Long-Term Opioid Use in Youth With Psychiatric Disorders

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Adolescents with anxiety, mood, neurodevelopmental, sleep, and nonopioid substance use disorders and most mental health treatments were significantly more likely to receive opioids.

Opioid Use Disorder Treatment: Evidence-Based Guideline

Opioid Use Disorder Treatment: Evidence-Based Guideline

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A new guideline recommends opioid agonist therapy with buprenorphine-naloxone as first-line for the treatment of opioid use disorder.

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

Too Early to Formulate Recommendations on Medical Cannabis vs Opioids for Pain?

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Various strategies to reduce opioid overdose deaths have been implemented and it has been suggested that access to medical cannabis may lead to a reduction in opioid use for pain management.

Comparing the Efficacy of Extended-Release Naltrexone and Buprenorphine-Naloxone on Opioid Relapse

Comparing the Efficacy of Extended-Release Naltrexone and Buprenorphine-Naloxone on Opioid Relapse

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Extended-release naltrexone and sublingual buprenorphine-naloxone were equally effective for preventing opioid abuse relapse.

Slow-Release Oral Morphine, a Promising Opioid Agonist Therapy Alternative to Buprenorphine, Methadone

Slow-Release Oral Morphine, a Promising Opioid Agonist Therapy Alternative to Buprenorphine, Methadone

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Slow-release oral morphine may be a valuable tool to help reduce the number of deaths from opioid-related overdose.

New Consensus Statement Establishes Guidelines on Urine Drug Monitoring in Chronic Pain

New Consensus Statement Establishes Guidelines on Urine Drug Monitoring in Chronic Pain

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New guidelines were formulated for the use of urine drug monitoring in risk stratification and the prevention of opioid use disorder, overdose, and diversion.

FDA Approves Once-Monthly Buprenorphine Injection for Opioid Use Disorder

FDA Approves Once-Monthly Buprenorphine Injection for Opioid Use Disorder

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In a press release issued November 30, 2017, the US Food and Drug Administration announced it has approved Sublocade, a once-monthly buprenorphine injection for moderate to severe opioid use disorder.

Immediate Access to Opioid Agonist Treatment Is Cost-Effective, Beneficial

Immediate Access to Opioid Agonist Treatment Is Cost-Effective, Beneficial

Immediate access to opioid agonist treatment for patients presenting with opioid use disorder may provide greater health benefits at less cost than observed standard of care.

Motivational Interview Intervention Reduces Opioid Overdose

Motivational Interview Intervention Reduces Opioid Overdose

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A motivational interviewing intervention delivered by trained counselors reduced the rate of opioid overdoses in participants with opioid use disorder.

Collaborative Care Superior to Standard Care for Opioid Use Disorder

Collaborative Care Superior to Standard Care for Opioid Use Disorder

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Patients with opioid and/or alcohol use disorders have better treatment access and greater rates of alcohol and drug abstinence at 6 months with collaborative care vs standard addiction care.

Tramadol Effective on Opioid Withdrawal Symptoms

Tramadol Effective on Opioid Withdrawal Symptoms

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The extended-release formulation of tramadol was shown to be as effective as buprenorphine and more effective than clonidine for treating symptoms of opioid withdrawal.

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

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Once-weekly subcutaneous buprenorphine injections block the euphoric effects of opioids and suppress opioid withdrawal in patients with opioid use disorder.

Buprenorphine and Naltrexone Underprescribed for Youth With Opioid Use Disorder

Buprenorphine and Naltrexone Underprescribed for Youth With Opioid Use Disorder

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Early pharmacologic intervention for opioid use disorder after diagnosis is crucial to prevent relapse and overdose in adolescents and young adults.

Discrepancies in Subjective vs Objective Sleep in Patients Receiving Buprenorphine for Opioid Use Disorder

Discrepancies in Subjective vs Objective Sleep in Patients Receiving Buprenorphine for Opioid Use Disorder

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Patients receiving buprenorphine maintenance therapy for their opioid use disorder may have impaired sleep, despite their reports of improved quality and duration of sleep.

High Mortality In Patients With Opioid Use Disorder In General Healthcare Setting

High Mortality In Patients With Opioid Use Disorder In General Healthcare Setting

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A recent study found high rates of mortality and morbidity in patients with opioid use disorder in a large healthcare system.

The Consequences of Limiting Physician Capacity to Rx Buprenorphine for Opioid Use Disorder

The Consequences of Limiting Physician Capacity to Rx Buprenorphine for Opioid Use Disorder

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The researchers found that novice prescribers cited insufficient access to substance abuse counseling for patients, as well as insufficient access to more experienced prescribers, as reasons for not treating more patients.

Rates of Opioid Agonist Therapy Prescriptions for Medicare Patients Reflect Treatment Gap

Rates of Opioid Agonist Therapy Prescriptions for Medicare Patients Reflect Treatment Gap

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A small fraction of prescriptions for Medicare patients are for opioid agonist therapy, despite higher rates of abuse.

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