Opioid Addiction

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant Medication Adherence and Long-Term Opioid Cessation

Antidepressant medication adherence is associated with cessation of long-term prescription opioid use among patients with non-cancer pain.

Opioid Use in Sepsis Linked to Higher Mortality

Opioid Use in Sepsis Linked to Higher Mortality

By

Higher mortality associated with opioid use in hospitalized patients with sepsis suggests an immunosuppressive effect that could contribute to worse outcomes.

Opioid Prescribing Trends in the Veterans Health Administration

Opioid Prescribing Trends in the Veterans Health Administration

Opioid prescribing trends in the Veterans Health Administration from 2010 to 2016 followed similar trajectories as non-VHA settings, peaking around 2012 then declining.

Evaluating Excessive NSAID Use in Ibuprofen Users

Evaluating Excessive NSAID Use in Ibuprofen Users

By

Fifteen percent of adults who took ibuprofen during a 1-week diary study exceeded the maximum recommended daily dose limit.

Electronic Medical Record "Nudge" May Shape Opioid Prescribing Behavior in the ED

Electronic Medical Record "Nudge" May Shape Opioid Prescribing Behavior in the ED

By

Implementation of electronic medical record default opioid prescriptions of 10 tablets of 5 mg oxycodone/325 mg acetaminophen at discharge from the ED may be associated with an increased percentage of prescriptions for 10 tablets, compared with no default.

Opioid Prescriptions for Musculoskeletal Conditions Increase Patient Satisfaction

Opioid Prescriptions for Musculoskeletal Conditions Increase Patient Satisfaction

The researchers found that 13.1% of patients with musculoskeletal conditions were opioid users, and those using prescribed opioids were more likely to be highly satisfied with their care.

Efficacy of Tamper-Resistant Controlled-Release Oxycodone

Efficacy of Tamper-Resistant Controlled-Release Oxycodone

The tamper-resistant formulation of controlled-release oxycodone in Australia reduced tampering among high-risk populations.

FDA Tentatively Approves Arymo ER Label Update for Abuse-Deterrent Claims

FDA Tentatively Approves Arymo ER Label Update for Abuse-Deterrent Claims

By

The FDA has tentatively approved an update to the Arymo ER extended-release tablets labeling to include data from an intranasal abuse-deterrent claim.

Topical Analgesics Aid Opioid Discontinuation, Pain Management

Topical Analgesics Aid Opioid Discontinuation, Pain Management

By

In a recent study, about half of the study patients taking opioids who were prescribed topical analgesics for pain management discontinued their opioids after 3 to 6 months of treatment.

Gabapentinoid Use Increased in the United States Over Last Decade

Gabapentinoid Use Increased in the United States Over Last Decade

From 2002 to 2015, the percentage of individuals in the United States who used gabapentin and/or pregabalin increased in 1.2% to 3.9%.

Ob-Gyns Opioid Prescribing Practices Need Improvement

Ob-Gyns Opioid Prescribing Practices Need Improvement

Improvement in obstetrician-gynecologists' knowledge and prescribing practices regarding opioids is needed.

Investigational Oxycodone Vaccine Shows Potential for Oxycodone Abuse, Overdose

Investigational Oxycodone Vaccine Shows Potential for Oxycodone Abuse, Overdose

By

An investigational vaccine may represent an effective treatment strategy for oxycodone abuse and may help reduce oxycodone overdose severity.

Chronic Pain Management in Primary Care Settings

Chronic Pain Management in Primary Care Settings

From helping patients with opioid addiction to finding pain management programs, one physician shares his experience with chronic pain management in the primary care setting.

High Risk for Prescription Opioid, Heroin Overdose in Baby Boomer Generation

High Risk for Prescription Opioid, Heroin Overdose in Baby Boomer Generation

Individuals born between 1947 and 1964 have a significantly increased risk for prescription opioid overdose death and heroin overdose death, and those born from 1979 to 1992 also have an increased risk of heroin overdose death.

Personalized Opioid Dosing Suggested Following Hysterectomy

Personalized Opioid Dosing Suggested Following Hysterectomy

Gynecologists prescribe about twice the amount of opioids than patients use after hysterectomy for benign, nonobstetric indications.

DEA Announces All Illicit Fentanyl Analogues Will Be Subject to Criminal Prosecution

DEA Announces All Illicit Fentanyl Analogues Will Be Subject to Criminal Prosecution

By

The announcement comes from the Department of Justice and will give the Drug Enforcement Agency the ability to take immediate action to stop illicit fentanyl from coming into the US.

Cannabis Use Associated With Relationship Between Pain and Negative Affect

Cannabis Use Associated With Relationship Between Pain and Negative Affect

By

Frequent cannabis users enrolled in a Medication-Assisted Treatment for opioid addiction exhibit greater associations between pain and negative affects compared with less-frequent users.

Obama Administration Senior Policy Advisor and Addiction Expert on White House Initiative to Address the Opioid Crisis

Obama Administration Senior Policy Advisor and Addiction Expert on White House Initiative to Address the Opioid Crisis

By

On October 30, 2017, the Clinton Foundation's Health Matters Initiative held a panel event at the Johns Hopkins Bloomberg School of Public Health for the release of a report co-written by these 2 organizations, titled "The Opioid Epidemic - From Evidence to Impact."

Opioid Crisis Declared Public Health Emergency by White House: Implications According to Pain Specialists

Opioid Crisis Declared Public Health Emergency by White House: Implications According to Pain Specialists

By

On October 26, 2017, President Trump declared the opioid epidemic a national public health emergency.

Opioid Epidemic Declared National Emergency by White House

Opioid Epidemic Declared National Emergency by White House

By

The opioid epidemic has been declared a national emergency by President Donald Trump, which means federal funding can be increased and directed toward treatment programs.

Long-Term Opioid Therapy Linked to Adverse Effects in Polyneuropathy

Long-Term Opioid Therapy Linked to Adverse Effects in Polyneuropathy

By

Long-term treatment with opioids is associated with more adverse outcomes in patients with polyneuropathy, including depression, overdose, and opioid dependence.

Migraine Treatment: Are Opioids Overprescribed?

Migraine Treatment: Are Opioids Overprescribed?

By

There are nearly as many migraine patients receiving opioids as there are patients receiving level A abortive medications.

Comprehensive Initiative Positively Impacts Opioid Prescribing

Comprehensive Initiative Positively Impacts Opioid Prescribing

After a comprehensive initiative to curb opioid prescribing, researchers identified reductions in all tracked outcomes, including a 30% decrease in prescribing opioids at high doses.

Tramadol Effective on Opioid Withdrawal Symptoms

Tramadol Effective on Opioid Withdrawal Symptoms

By

The extended-release formulation of tramadol was shown to be as effective as buprenorphine and more effective than clonidine for treating symptoms of opioid withdrawal.

Screeners to Predict Opioid Misuse in Patients With Chronic Pain

Screeners to Predict Opioid Misuse in Patients With Chronic Pain

By

Rates of opioid misuse and related overdoses have soared in recent years in the United States, highlighting the importance of screening tools to identify patients at high risk for adverse events from opioid use.

CDC: Opioid Rx Rate Remains High, Inconsistent in the US

CDC: Opioid Rx Rate Remains High, Inconsistent in the US

By

The number of opioids prescribed in the US decreased between 2010 and 2015, but the overall rate remains high.

Strategies to Curb the Opioid Epidemic: A National Academies Report

Strategies to Curb the Opioid Epidemic: A National Academies Report

By

Highlights from the National Academies of Sciences, Engineering, and Medicine report titled "Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use."

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

Buprenorphine Injections Effective on Opioid-Associated Euphoria and Withdrawal

By

Once-weekly subcutaneous buprenorphine injections block the euphoric effects of opioids and suppress opioid withdrawal in patients with opioid use disorder.

Opioid Prescriptions Remains High According to CDC

Opioid Prescriptions Remains High According to CDC

By

According to the CDC, despite reductions in certain parts of the country, the amount of opioids being prescribed remains high compared with levels in 1999, with variations mostly seen at the county level.

Neonatal Abstinence Syndrome Effectively Treated With Buprenorphine

Neonatal Abstinence Syndrome Effectively Treated With Buprenorphine

In infants with neonatal abstinence syndrome, sublingual buprenorphine reduced the duration of treatment and decreased the length of hospital stay.

Sign Up for Free e-Newsletters