Unsolicited notices to prescribers as part of prescription drug monitoring programs may not effectively reduce opioid use, as patients may seek other prescribers.
Abuse-deterrent opioid formulations have not yet been widely accepted despite their proposed value in reducing opioid abuse and related mortality. Many of the current barriers to broader use are related to their higher cost compared with conventional formulations.
All healthcare providers have a role in combating the opioid use disorder epidemic and its infectious disease consequences.
Studies comparing MMT to buprenorphine maintenance treatment (BMT) over 5-years found buprenorphine to be a safer drug for opioid maintenance treatment as it had no significant effect on QT prolongation.
In a communiqué issued on August 6, 2018, the US Food and Drug Administration announced the release of a draft guidance titled, "Opioid Use Disorder: Endpoints for Demonstrating Effectiveness of Drugs for Medication-Assisted Treatment - Guidance for Industry."
Despite the availability of long-acting opioid antagonists, many patients with OUD never receive adequate treatment.
Lucemyra is not indicated as a treatment for opioid use disorder.
States that have adopted Medicaid expansions under the Affordable Care Act saw an increase in the utilization and availability of treatments for opioid use disorder.
These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.
Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.
In women with opioid use disorder, greater distress tolerance may be associated with fewer alcohol use days.
Pregnant women receiving medication therapy for addiction can be prescribed higher doses of buprenorphine without increasing the risk or severity of neonatal abstinence syndrome.
Preoperative opioid use is reported in 23.1 percent of patients undergoing surgery.
Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic PainJuly 18, 2018
The Prescribed Opioids Difficulties Scale may be effective for identifying patients using opioids for chronic noncancer pain who are worried about their usage.
A novel, innovative initiative is being developed to help end addiction over the long term, according to a viewpoint article published online June 12 in the Journal of the American Medical Association.
In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.
Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.
Shame to those who use opioids are based on more evidence than what society perceives.
CDC Report: Integrating Tobacco Cessation Interventions in Mental Health, Substance Abuse Treatment FacilitiesJune 14, 2018
Providing barrier-free access to proven cessation treatments is critical to reduce smoking-related disease and death in the United States.
With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.
While many treatments for substance use disorder are not evidence based, several evidence-based approaches have shown effectiveness in court-mandated treatment settings.
Legislation that requires prescribers to check Ohio's Prescription Drug Monitoring Program was found to lead to a reduction in the quantity of opioids and benzodiazepines dispensed.
The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.
From 2001 to 2016 there was an increase in the number and percentage of opioid-related deaths; in addition, most patients receiving opioids receive immediate-release formulations.
NKTR-181 is a long-acting selective full mu-opioid agonist.
Patients will still be at risk for schizophrenia or bipolar disorder even several years after an episode of substance-induced psychosis.
The number of transplants of organs from brain-dead donors has risen sharply in the United States, primarily due to the increase in mortality associated with the drug-abuse epidemic.
Two lots of naloxone hydrochloride injections, USP have been recalled by Hospira, Inc., due to concerns regarding the presence of particulates on the syringe plunger.
Investigators compared rates of opioid injection drug use with the incidence of acute HCV infection in the United States.
Researchers used vital statistics data to examine whether increases in mortality rates and years of potential life lost among midlife non-Hispanic whites from 1999 to 2015 are associated with increases in fatal overdoses.
Clinical Pain Advisor Articles
- Opioid Use Disorders: Advances in Pharmacotherapy Provide Long-term Results
- Abuse-Deterrent Opioid Formulations: Barriers to Broader Use
- Women Frequently Prescribed High Doses of Opioids After Vaginal Delivery
- Notifications by PDMPs May Not Effectively Reduce Opioid Misuse
- Medical Cannabis Legalization Associated With Reduced Schedule III Opioid Prescriptions
- Neuropathic Pain Medications
- Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome
- Terms Used for Addiction May Be Associated With Explicit, Implicit Bias
- Ketamine Infusions May Be Effective for Refractory Headache
- Physical, Psychosocial Activity May Be Protective Against Development of Chronic Pain in Older Adults
- Cancer Patients Treated With Step III Opioids Often Have Sleep Disturbances
- Individual, Group Low Literacy Self-Management Program for Chronic Pain May Be Effective
- AMA Proposes Policy Opposing Medicaid 'Lockout' Provisions
- Steps Can Be Taken by Doctors to Minimize Risk of Lawsuits
- Learning to Change Important for Improving Practice