Opioid Addiction

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Reducing Mortality After Overdose: Is Treatment for Opioid Use Disorder Effective?

Reducing Mortality After Overdose: Is Treatment for Opioid Use Disorder Effective?

Adults who received pharmacologic treatment for opioid use disorder following a non-fatal overdose may have a reduced risk for opioid-related and all-cause mortality in the subsequent 12 months compared with adults who did not receive medication-assisted treatment.

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Opioid Use Disorder Prevalence at Delivery on the Rise in the US, According to CDC

Opioid Use Disorder Prevalence at Delivery on the Rise in the US, According to CDC

The prevalence of opioid use disorder rose in women delivering at hospitals across 28 US states and the District of Columbia between 1999 and 2014, with quadrupling at the national level during this period.

Notifications by PDMPs May Not Effectively Reduce Opioid Misuse

Notifications by PDMPs May Not Effectively Reduce Opioid Misuse

Unsolicited notices to prescribers as part of prescription drug monitoring programs may not effectively reduce opioid use, as patients may seek other prescribers.

Integrating Treatments for Opioid Use Disorder and Infectious Diseases

Integrating Treatments for Opioid Use Disorder and Infectious Diseases

All healthcare providers have a role in combating the opioid use disorder epidemic and its infectious disease consequences.

Which Opioids Are More Likely to Induce QT Interval Prolongation?

Which Opioids Are More Likely to Induce QT Interval Prolongation?

Studies comparing MMT to buprenorphine maintenance treatment (BMT) over 5-years found buprenorphine to be a safer drug for opioid maintenance treatment as it had no significant effect on QT prolongation.

Assessing Medication-Assisted Treatments: FDA Guidance for Drug Developers

Assessing Medication-Assisted Treatments: FDA Guidance for Drug Developers

In a communiqué issued on August 6, 2018, the US Food and Drug Administration announced the release of a draft guidance titled, "Opioid Use Disorder: Endpoints for Demonstrating Effectiveness of Drugs for Medication-Assisted Treatment - Guidance for Industry."

Lucemyra Now Available for Mitigation of Opioid Withdrawal Symptoms

Lucemyra Now Available for Mitigation of Opioid Withdrawal Symptoms

Lucemyra is not indicated as a treatment for opioid use disorder.

Medicaid Expansion Under ACA Found to Benefit Access to Treatments for Opioid Use Disorder

Medicaid Expansion Under ACA Found to Benefit Access to Treatments for Opioid Use Disorder

States that have adopted Medicaid expansions under the Affordable Care Act saw an increase in the utilization and availability of treatments for opioid use disorder.

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

Individuals taking opioids were found to be more likely to report physical and mental health issues and to have more frequent dealings with the criminal justice system compared with individuals not taking opioids.

Therapy Focusing on Mindfulness Improves Outcomes for Women With Substance Use Disorder

Therapy Focusing on Mindfulness Improves Outcomes for Women With Substance Use Disorder

These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.

Debunking Myths Around Treatment for Opioid Use Disorder

Debunking Myths Around Treatment for Opioid Use Disorder

Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.

Distress Tolerance Associated With Alcohol Use in Women With Opioid Use Disorder

Distress Tolerance Associated With Alcohol Use in Women With Opioid Use Disorder

In women with opioid use disorder, greater distress tolerance may be associated with fewer alcohol use days.

Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome

Higher Buprenorphine Dose May Not Increase Severity of Neonatal Abstinence Syndrome

Pregnant women receiving medication therapy for addiction can be prescribed higher doses of buprenorphine without increasing the risk or severity of neonatal abstinence syndrome.

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Preoperative opioid use is reported in 23.1 percent of patients undergoing surgery.

Terms Used for Addiction May Be Associated With Explicit, Implicit Bias

Terms Used for Addiction May Be Associated With Explicit, Implicit Bias

Stigmatizing terms used to describe individuals who have a substance addiction, including "addict," alcoholic," and "substance abuser," may be associated with negative explicit and implicit biases and should be replaced with positive terms that still describe the conditions accurately.

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone Improves Short-Term Outcomes Better Than Morphine in Neonatal Abstinence Syndrome

Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.

Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain

Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain

The Prescribed Opioids Difficulties Scale may be effective for identifying patients using opioids for chronic noncancer pain who are worried about their usage.

U.S. Surgeon General Urges More Americans to Carry Naloxone

U.S. Surgeon General Urges More Americans to Carry Naloxone

As the rates of opioid overdose deaths are increasing rapidly, the Surgeon General is recommending that more individuals, including family, friends, and those who are personally at risk for an opioid overdose.

Predictors of Opioid Overdose in High-Risk Users

Predictors of Opioid Overdose in High-Risk Users

Having a hepatitis C virus infection, witnessing a friend or others experiencing a drug overdose, and having a history of frequent buprenorphine treatment are factors that may predict the risk for opioid drug overdose in high-risk opioid users.

FDA to Review Long-Acting Treatment for Opioid Use Disorder

FDA to Review Long-Acting Treatment for Opioid Use Disorder

Pending approval, CAM2038 may be the first long-acting treatment for OUD in both weekly and monthly formulations.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.