Adults who received pharmacologic treatment for opioid use disorder following a non-fatal overdose may have a reduced risk for opioid-related and all-cause mortality in the subsequent 12 months compared with adults who did not receive medication-assisted treatment.
The prevalence of opioid use disorder rose in women delivering at hospitals across 28 US states and the District of Columbia between 1999 and 2014, with quadrupling at the national level during this period.
Unsolicited notices to prescribers as part of prescription drug monitoring programs may not effectively reduce opioid use, as patients may seek other prescribers.
All healthcare providers have a role in combating the opioid use disorder epidemic and its infectious disease consequences.
Studies comparing MMT to buprenorphine maintenance treatment (BMT) over 5-years found buprenorphine to be a safer drug for opioid maintenance treatment as it had no significant effect on QT prolongation.
In a communiqué issued on August 6, 2018, the US Food and Drug Administration announced the release of a draft guidance titled, "Opioid Use Disorder: Endpoints for Demonstrating Effectiveness of Drugs for Medication-Assisted Treatment - Guidance for Industry."
Lucemyra is not indicated as a treatment for opioid use disorder.
States that have adopted Medicaid expansions under the Affordable Care Act saw an increase in the utilization and availability of treatments for opioid use disorder.
Individuals taking opioids were found to be more likely to report physical and mental health issues and to have more frequent dealings with the criminal justice system compared with individuals not taking opioids.
These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.
Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.
In women with opioid use disorder, greater distress tolerance may be associated with fewer alcohol use days.
Pregnant women receiving medication therapy for addiction can be prescribed higher doses of buprenorphine without increasing the risk or severity of neonatal abstinence syndrome.
Preoperative opioid use is reported in 23.1 percent of patients undergoing surgery.
Stigmatizing terms used to describe individuals who have a substance addiction, including "addict," alcoholic," and "substance abuser," may be associated with negative explicit and implicit biases and should be replaced with positive terms that still describe the conditions accurately.
Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.
Prescribed Opioids Difficulties Scale Effective for Assessing Concerns of Patients With Chronic Pain
The Prescribed Opioids Difficulties Scale may be effective for identifying patients using opioids for chronic noncancer pain who are worried about their usage.
As the rates of opioid overdose deaths are increasing rapidly, the Surgeon General is recommending that more individuals, including family, friends, and those who are personally at risk for an opioid overdose.
Having a hepatitis C virus infection, witnessing a friend or others experiencing a drug overdose, and having a history of frequent buprenorphine treatment are factors that may predict the risk for opioid drug overdose in high-risk opioid users.
Pending approval, CAM2038 may be the first long-acting treatment for OUD in both weekly and monthly formulations.
American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.
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