Could Melatonin Help Fibromyalgia Pain?
the Clinical Pain Advisor take:
Even though Melatonin is commonly used as a sleeping pill -- it might serve another purpose. A new study revealed that Melatonin could alleviate pain symptoms resulting from fibromyalgia.
Researchers learned that high dose Melatonin taken regularly for six weeks probably reduces fibromyalgia pain. The report outlines an analysis of 63 women with fibromyalgia. The study's authors randomized patients to receive either 25 mgs of amitriptyline or 10 mgs of Melatonin or amitryptiline and melatonin together. Doses were given at bedtime.
The study's findings showed that patients in all three groups had less pain after six weeks than they did at baseline. Intensity was scored using a Visual Analogue Scale (zero means no pain and 100 means the worst possible pain).
In an analysis of the report, Richard N. Podell, MD, MPH, said it's fair to assume that Melatonin is likely to be a useful. "And because side effects from Melatonin are only rarely a problem, a trial of treatment with Melatonin with or without amitryptiline might be considered," he said.
He did point out, however, that most people typically don't use Melatonin the same way the study did. "So anyone using Melatonin to help fibromyalgia pain should be prepared to take it every night for six weeks before judging whether or not it helps," he said.
Researchers learned that high dose Melatonin taken regularly for six weeks probably reduces fibromyalgia pain.
Clinical Pain Advisor Articles
- Low Back Pain: Contributing Factors, Prophylactic Strategies, and Effective Treatments
- Betel Quid Addiction and Implications for Substance Use Disorder
- Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain
- New Blood Test Shows High Accuracy for Diagnosing Fibromyalgia
- Positive Affect, Resilience, and Pain in MS With Chronic Pain
- Exploring the Connections Between Neuropathic Pain and Comorbid Mood Disorders
- Medical Marijuana Laws, Dispensaries May Reduce Deaths From Opioid Overdose
- Ketamine Infusion May Be Effective for the Short-Term Relief of CRPS-Associated Pain
- An Avenue for the Development of Opioid Adjuncts for Enhanced Analgesia, Reduced Abuse Potential
- Peripheral Neuropathy Management in the Primary Care Setting: A Guide
- Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain
- Conventional vs High-Frequency Spinal Cord Stimulation for Chronic Pain
- Evaluating Headache in the Elderly: Primary vs Secondary Causes
- Custom Foot Orthotics vs OTC Insoles for Plantar Heel Pain
- Once-Monthly Erenumab Injections May Be Effective for Episodic Migraine Prophylaxis