Neuropathic Pain

Sustained-Release Sodium Nitrite for Diabetic Neuropathic Pain Not Associated With Headaches

Sustained-Release Sodium Nitrite for Diabetic Neuropathic Pain Not Associated With Headaches

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A sustained-release formulation of sodium nitrite may not be associated with headaches and dizziness reported by patients treated with the immediate-release formulation of sodium nitrite for diabetic peripheral neuropathy.

EEG Features as Markers of Neuropathic Pain in Spinal Cord Injury

EEG Features as Markers of Neuropathic Pain in Spinal Cord Injury

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Patients with subacute spinal cord injury may present electroencephalographic features that predate the onset of neuropathic pain and may serve both as markers and predictors of neuropathic pain.

Point-of-Care Conduction Device May Accurately Screen for Polyneuropathy in At-Risk Populations

Point-of-Care Conduction Device May Accurately Screen for Polyneuropathy in At-Risk Populations

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A point-of-care conduction device may provide accurate measurements of nerve amplitude potential and conduction velocity for the diagnosis of polyneuropathy in older patients.

Capsaicin 8% Patch May Be Effective in Neuropathic Pain

Capsaicin 8% Patch May Be Effective in Neuropathic Pain

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The use of a topical capsaicin 8%may be effective in neuropathic pain associated with postherpetic neuralgia or resulting from trauma or surgery.

Clinical and Research Applications of Screening and Assessment Questionnaires for Neuropathic Pain

Clinical and Research Applications of Screening and Assessment Questionnaires for Neuropathic Pain

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Specific countries officially recommend some screening questionnaires for the early assessment of neuropathic pain, with France recommending the DN4 and Germany recommending PainDETECT.

Factors Associated With Neuropathic Pain in Ankylosing Spondylitis

Factors Associated With Neuropathic Pain in Ankylosing Spondylitis

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A number of factors that include age, the presence of enthesitis, and depressive symptoms may be associated with neuropathic pain in ankylosing spondylitis.

Catastrophizing and Function in Chronic Spinal Pain

Catastrophizing and Function in Chronic Spinal Pain

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Pain catastrophizing may be associated with reduced psychological — and to a lesser extent physical —function in patients with neuropathic pain and spinal pain.

Severe MS Associated With Increased Neuropathic Pain Risk

Severe MS Associated With Increased Neuropathic Pain Risk

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Neuropathic pain is associated with a more severe multiple sclerosis disease phenotype.

Reviewing the Efficacy, Safety, and Tolerability of Cannabis-Based Medicines for Chronic Neuropathic Pain

Reviewing the Efficacy, Safety, and Tolerability of Cannabis-Based Medicines for Chronic Neuropathic Pain

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The effectiveness of cannabis-based products for chronic neuropathic pain is not supported by high-quality evidence.

ZTlido Approved to Treat Pain Associated With Postherpetic Neuralgia

ZTlido Approved to Treat Pain Associated With Postherpetic Neuralgia

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ZTlido is comprised of a non-aqueous adhesive material containing 1.8% lidocaine.

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

Peripherally Acting Opioid and Cannabinoid May Be Effective for Neuropathic Pain

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Cotargeting of peripheral μ-opioid and cannabinoid receptors was found to have a synergistic effect in reducing mechanical allodynia in a mouse model of neuropathic pain.

Peripheral Neuropathy Management in the Primary Care Setting: A Guide

Peripheral Neuropathy Management in the Primary Care Setting: A Guide

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Although peripheral neuropathy is one of the most common neurologic problems seen in the primary care setting, recognizing and evaluating peripheral neuropathy in a patient can be challenging due to its diverse presentations.

Bedside Quantitative Sensory Testing May Reliably Assess Sensory Profiles in Neuropathic Pain

Bedside Quantitative Sensory Testing May Reliably Assess Sensory Profiles in Neuropathic Pain

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A bedside quantitative sensory testing using inexpensive handheld devices indicates that this test may reliably be used to assess sensory profiles in patients with neuropathic pain.

Safety, Efficacy of Lidocaine Infusion for Prolonged Neuropathic Pain

Safety, Efficacy of Lidocaine Infusion for Prolonged Neuropathic Pain

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Investigators sought to determine whether repeated intravenous low-dose lidocaine could provide prolonged pain relief in patients with refractory neuropathic pain.

Gluten-Free Diet May Relieve Peripheral Neuropathic Pain

Gluten-Free Diet May Relieve Peripheral Neuropathic Pain

For patients with gluten neuropathy, following a strict gluten-free diet is associated with significantly reduced odds of peripheral neuropathic pain.

Exploring the Connections Between Neuropathic Pain and Comorbid Mood Disorders

Exploring the Connections Between Neuropathic Pain and Comorbid Mood Disorders

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Substantial evidence suggests a close connection between neuropathic pain and mood disorders.

Weighted Score May Help in Diagnosing CRPS

Weighted Score May Help in Diagnosing CRPS

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Researchers have developed a weighted score that may be useful in the differential diagnosis of complex regional pain syndrome.

Optimal Approaches to the Management of Burn Pain: Expert Insight

Optimal Approaches to the Management of Burn Pain: Expert Insight

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Depending on the extent of the injury, pain due to burns can range from mild to severe to excruciating.

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

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Systemic lidocaine administered via IV or patch has consistently shown effectiveness for the treatment and prevention of chronic pain.

Neuropathic Pain Common in End-Stage Knee, Hip Osteoarthritis

Neuropathic Pain Common in End-Stage Knee, Hip Osteoarthritis

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Patients with end-stage knee or hip osteoarthritis were found to often experience possible neuropathic pain - particularly pain at rest vs on activity, and in men.

Updated Criteria for CRPS Diagnosis May Reveal Presence of Neuropathic Pain After TKA

Updated Criteria for CRPS Diagnosis May Reveal Presence of Neuropathic Pain After TKA

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Use of the 2006 vs 2007 criteria for the diagnosis of complex regional pain syndrome may lead to the misdiagnosis of patients experiencing unexplained excessive pain after total knee arthroplasty.

New Guidelines for Opioid Use in Refractory Restless Leg Syndrome

New Guidelines for Opioid Use in Refractory Restless Leg Syndrome

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Opioids may be "life-transforming" for patients with refractory restless legs syndrome when taken in relatively low total daily doses, according to new guidelines.

Limited Evidence for the Effectiveness of Oxcarbazepine in Neuropathic Pain

Limited Evidence for the Effectiveness of Oxcarbazepine in Neuropathic Pain

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Evidence for the effectiveness of oxcarbazepine in painful diabetic neuropathy and other forms of neuropathic pain is limited.

Capsaicin Patch Superior to Pregabalin for Alleviating, Resolving Dynamic Mechanical Allodynia

Capsaicin Patch Superior to Pregabalin for Alleviating, Resolving Dynamic Mechanical Allodynia

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Treatment with the capsaicin 8% patch Qutenza may be more effective than pregabalin for reducing the intensity and area of dynamic mechanical allodynia and for complete resolution of the disorder.

Chronic Pain in Pachyonychia Congenita May Have Neuropathic Origin

Chronic Pain in Pachyonychia Congenita May Have Neuropathic Origin

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Chronic pain experienced by patients with pachyonychia congenita may be caused by damage to the peripheral nerve fibers, with the hyperalgesia and allodynia observed in affected regions likely to be manifestations of peripheral sensitization.

Peripheral Nerve Stimulation May Provide Long-Term Pain Relief for Leprosy-Related Mononeuropathy

Peripheral Nerve Stimulation May Provide Long-Term Pain Relief for Leprosy-Related Mononeuropathy

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Peripheral nerve stimulation may provide long-term pain relief in patients with painful mononeuropathy secondary to leprosy.

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

After 5 years, 55% of patients had experienced treatment success and 80% of patients with a permanent implant still used their SCS device.

Pain in Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach

Pain in Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach

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Pain management in athletes requires a clear understanding of the different types of pain and various factors that can contribute to pain in this population.

Virtual Reality Effective on Spinal Cord Injury-Related Chronic Neuropathic Pain

Virtual Reality Effective on Spinal Cord Injury-Related Chronic Neuropathic Pain

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The use of virtual reality (VR) and multisensory stimulation in patients with spinal cord injury promotes mild relief from chronic neuropathic pain and represents a potentially helpful addition to SCI neurorehabilitation management.

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

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In patients with multiple sclerosis, lesions in the right dorsolateral prefrontal cortex and posterior periventricular area may be associated with hypo and hyperalgesia.

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