Neuropathic Pain

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

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The use of capsaicin 8% patch repeat treatment is well tolerated and may provide effective long-term benefit in patients with peripheral neuropathic pain.

Chemo-Induced Peripheral Neuropathy Risk Reduced With Multivitamin

Chemo-Induced Peripheral Neuropathy Risk Reduced With Multivitamin

Multivitamin use before diagnosis of breast cancer is associated with reduced risk of symptoms of chemotherapy-induced peripheral neuropathy.

Cannabis for Neuropathic Pain: What Evidence Is There?

Cannabis for Neuropathic Pain: What Evidence Is There?

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There is currently little conclusive evidence to suggest a benefit of cannabis use for the management of neuropathic pain.

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

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The use of gabapentin, pregabalin, or both is effective for reducing pruritus and neuropathic pain in burn survivors.

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

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Patients with neuropathic pain are more likely to achieve effective therapeutic dose when treated with pregabalin compared with gabapentin.

Vitamin D Deficiency Associated With Neuropathic Pain in Rheumatoid Arthritis

Vitamin D Deficiency Associated With Neuropathic Pain in Rheumatoid Arthritis

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In patients with rheumatoid arthritis, vitamin D deficiency was shown to be associated with increased neuropathic pain.

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

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Preemptive analgesia seeks to prevent central sensitization and ensuing chronic pain, a concept that has shown promising results in preliminary studies.

Intravenous Lidocaine Safe, Effective for Chronic Pain

Intravenous Lidocaine Safe, Effective for Chronic Pain

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Lidocaine infusions were shown to provide long-lasting and adequate analgesia in 41% of patients with chronic pain.

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Patients with neuropathic pain who do not respond to a low dose of pregabalin can benefit from a higher dose.

Neuropathic Pain Medications

Chart with medications used to treat neuropathic pain, including diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia.

Updated Diagnostic Criteria for Neuropathic Pain in SCI, Stroke, MS

Updated Diagnostic Criteria for Neuropathic Pain in SCI, Stroke, MS

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The diagnostic criteria formulated by the ACTTION-APS Pain Taxonomy working group focus on neuropathic pain from SCI, stroke, and MS.

Orexin Receptor Antagonist Ineffective on Painful Diabetic Neuropathy

Orexin Receptor Antagonist Ineffective on Painful Diabetic Neuropathy

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Filorexant is not effective in relieving painful diabetic neuropathy-related pain.

Neuropathic Pain in Low Back-Related Leg Pain: the State of Evidence

Neuropathic Pain in Low Back-Related Leg Pain: the State of Evidence

A systematic review points to a dearth of evidence regarding the neuropathic etiology of low back-related leg pain.

Current State of Evidence on Ketamine: Uses, Effects, Research

Current State of Evidence on Ketamine: Uses, Effects, Research

Ketamine was found to alleviate several pain modalities, and a number of clinical trials investigating its efficacy are ongoing.

Gabapentin Assessed in Chronic Neuropathic Pain

Gabapentin Assessed in Chronic Neuropathic Pain

Gabapentin, at doses of 1800 mg to 3600 mg can provide "good levels of pain relief" to some individuals suffering from postherpetic neuralgia and peripheral diabetic neuropathy.

Cannabinoids May Provide Limited Relief From Neuropathic Pain

Cannabinoids May Provide Limited Relief From Neuropathic Pain

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Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.

Trigeminal Neuralgia: Assessing Treatment Patterns to Improve Outcomes

Trigeminal Neuralgia: Assessing Treatment Patterns to Improve Outcomes

In a 3-year period, 45% of patients with trigeminal neuralgia received at least 3 unique treatments.

Bortezomib-Induced Neuropathy From First to Second Treatment for Multiple Myeloma

Bortezomib-Induced Neuropathy From First to Second Treatment for Multiple Myeloma

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Bortezomib-induced peripheral neuropathy does not worsen between initial treatment and retreatment in patients with multiple myeloma.

Antidepressant Serum Levels may be Lower in Cigarette Smokers

Antidepressant Serum Levels may be Lower in Cigarette Smokers

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Serum concentration levels of several antidepressants were lower in cigarette smokers vs non-smokers.

Preclinical Pain as a Marker for Amyotrophic Lateral Sclerosis

Preclinical Pain as a Marker for Amyotrophic Lateral Sclerosis

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Pain is far more common and widespread in ALS than previously suspected, and initial pain symptoms may predate the clinical onset of the disease's hallmark motor dysfunction by as much as 2 years.

Pregabalin for Sciatica: Is It Effective?

Pregabalin for Sciatica: Is It Effective?

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In patients with sciatica pain, treatment with pregabalin did not significantly reduce pain intensity compared with placebo.

Neuropathic Pain Complexity Requires Thoughtful Approach and Combination of Interventions

Neuropathic Pain Complexity Requires Thoughtful Approach and Combination of Interventions

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The wide range of etiologies underlying neuropathic pain render it a particularly challenging condition to manage.

Central Neuropathic Pain Syndromes

Central Neuropathic Pain Syndromes

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Differentiating central neuropathic pain from musculoskeletal or peripheral neuropathic pain can be challenging.

Optimal Management of Post-mastectomy Pain Syndrome

Optimal Management of Post-mastectomy Pain Syndrome

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Limited data suggest antidepressants, topical capsaicin, and fat grafting may reduce pain associated with post-mastectomy pain syndrome, but more and better studies are needed to determine optimal management for this debilitating condition.

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

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Viewing photographs can decrease pain intensity in patients with chronic pain.

Proliferative Diabetic Retinopathy: Outcomes With Ranibizumab vs Panretinal Photocoagulation

Proliferative Diabetic Retinopathy: Outcomes With Ranibizumab vs Panretinal Photocoagulation

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Cumulative probability of proliferative diabetic retinopathy worsening was 42% in the panretinal photocoagulation group vs 34% in the ranibizumab group.

Classification of Peripheral Neuropathic Pain Based on Sensory Profiles

Classification of Peripheral Neuropathic Pain Based on Sensory Profiles

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Researchers identified 3 subgroups of patients with peripheral neuropathic pain, based on sensory signs and symptoms.

Assessing Pregabalin Efficacy With Concomitant Neuropathic Pain Medications

Assessing Pregabalin Efficacy With Concomitant Neuropathic Pain Medications

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The therapeutic efficacy of pregabalin in treating 2 types neuropathic pain (NeP) is not influenced by concomitant NeP medications.

Costs of Pregabalin vs Gabapentin for Peripheral Neuropathic Pain

Costs of Pregabalin vs Gabapentin for Peripheral Neuropathic Pain

Lower cost for pregabalin Tx due to lower use of concomitant medications, fewer primary care visits, and fewer days of sick leave.

Proposed Algorithm to Diagnose, Treat Neuropathic Pain

Proposed Algorithm to Diagnose, Treat Neuropathic Pain

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A research group developed the algorithm through a year-long process of reviewing data, sharing their own clinical experiences, and considering feedback from geriatric and pain societies.

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