The use of capsaicin 8% patch repeat treatment is well tolerated and may provide effective long-term benefit in patients with peripheral neuropathic pain.
Multivitamin use before diagnosis of breast cancer is associated with reduced risk of symptoms of chemotherapy-induced peripheral neuropathy.
There is currently little conclusive evidence to suggest a benefit of cannabis use for the management of neuropathic pain.
The use of gabapentin, pregabalin, or both is effective for reducing pruritus and neuropathic pain in burn survivors.
Patients with neuropathic pain are more likely to achieve effective therapeutic dose when treated with pregabalin compared with gabapentin.
In patients with rheumatoid arthritis, vitamin D deficiency was shown to be associated with increased neuropathic pain.
Preemptive analgesia seeks to prevent central sensitization and ensuing chronic pain, a concept that has shown promising results in preliminary studies.
Lidocaine infusions were shown to provide long-lasting and adequate analgesia in 41% of patients with chronic pain.
Patients with neuropathic pain who do not respond to a low dose of pregabalin can benefit from a higher dose.
Chart with medications used to treat neuropathic pain, including diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia.
The diagnostic criteria formulated by the ACTTION-APS Pain Taxonomy working group focus on neuropathic pain from SCI, stroke, and MS.
Filorexant is not effective in relieving painful diabetic neuropathy-related pain.
A systematic review points to a dearth of evidence regarding the neuropathic etiology of low back-related leg pain.
Ketamine was found to alleviate several pain modalities, and a number of clinical trials investigating its efficacy are ongoing.
Gabapentin, at doses of 1800 mg to 3600 mg can provide "good levels of pain relief" to some individuals suffering from postherpetic neuralgia and peripheral diabetic neuropathy.
Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.
In a 3-year period, 45% of patients with trigeminal neuralgia received at least 3 unique treatments.
Bortezomib-induced peripheral neuropathy does not worsen between initial treatment and retreatment in patients with multiple myeloma.
Serum concentration levels of several antidepressants were lower in cigarette smokers vs non-smokers.
Pain is far more common and widespread in ALS than previously suspected, and initial pain symptoms may predate the clinical onset of the disease's hallmark motor dysfunction by as much as 2 years.
In patients with sciatica pain, treatment with pregabalin did not significantly reduce pain intensity compared with placebo.
The wide range of etiologies underlying neuropathic pain render it a particularly challenging condition to manage.
Differentiating central neuropathic pain from musculoskeletal or peripheral neuropathic pain can be challenging.
Limited data suggest antidepressants, topical capsaicin, and fat grafting may reduce pain associated with post-mastectomy pain syndrome, but more and better studies are needed to determine optimal management for this debilitating condition.
Viewing photographs can decrease pain intensity in patients with chronic pain.
Cumulative probability of proliferative diabetic retinopathy worsening was 42% in the panretinal photocoagulation group vs 34% in the ranibizumab group.
Researchers identified 3 subgroups of patients with peripheral neuropathic pain, based on sensory signs and symptoms.
The therapeutic efficacy of pregabalin in treating 2 types neuropathic pain (NeP) is not influenced by concomitant NeP medications.
Lower cost for pregabalin Tx due to lower use of concomitant medications, fewer primary care visits, and fewer days of sick leave.
A research group developed the algorithm through a year-long process of reviewing data, sharing their own clinical experiences, and considering feedback from geriatric and pain societies.
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