Neuropathic Pain

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Peripheral Nerve Surgery for Burn Survivors: Improving Outcomes Through Clinician Self-Analysis

Peripheral Nerve Surgery for Burn Survivors: Improving Outcomes Through Clinician Self-Analysis

As survival rates for patients with burns have improved, the need for effective treatments for chronic pain in this population has become more pressing.

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Chemonucleolysis With Radiopaque Gelified Ethanol May Be Effective Analgesic for Chronic Radicular Pain

Chemonucleolysis With Radiopaque Gelified Ethanol May Be Effective Analgesic for Chronic Radicular Pain

The use of percutaneous chemonucleolysis with radiopaque gelified ethanol may be safe and effective for patients with treatment-resistant chronic radicular leg pain.

Peripheral Nerve Stimulation May Provide Long-Term Pain Relief for Leprosy-Related Mononeuropathy

Peripheral Nerve Stimulation May Provide Long-Term Pain Relief for Leprosy-Related Mononeuropathy

Peripheral nerve stimulation may provide long-term pain relief in patients with painful mononeuropathy secondary to leprosy.

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

Spinal Cord Stimulation Reduces Pain Associated With Diabetic Polyneuropathy

After 5 years, 55% of patients had experienced treatment success and 80% of patients with a permanent implant still used their SCS device.

Acupuncture May Alleviate Pain in Idiopathic Trigeminal Neuralgia

Acupuncture May Alleviate Pain in Idiopathic Trigeminal Neuralgia

Acupuncture may reduce pain intensity and mechanical thresholds in patients with idiopathic trigeminal neuralgia.

Pain In Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach

Pain In Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach

Pain management in athletes requires a clear understanding of the different types of pain and various factors that can contribute to pain in this population.

Virtual Reality Effective on Spinal Cord Injury-Related Chronic Neuropathic Pain

Virtual Reality Effective on Spinal Cord Injury-Related Chronic Neuropathic Pain

The use of virtual reality (VR) and multisensory stimulation in patients with spinal cord injury promotes mild relief from chronic neuropathic pain and represents a potentially helpful addition to SCI neurorehabilitation management.

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

Hypoalgesia, Hyperalgesia Linked to Multiple Sclerosis Lesion Location

In patients with multiple sclerosis, lesions in the right dorsolateral prefrontal cortex and posterior periventricular area may be associated with hypo and hyperalgesia.

Dronabinol Safe and Effective for Neuropathic Pain Associated With Multiple Sclerosis

Dronabinol Safe and Effective for Neuropathic Pain Associated With Multiple Sclerosis

Dronabinol provides a safe and effective treatment option for patients with symptoms of neuropathic pain associated with multiple sclerosis.

Peripheral Neuropathy in Patients With HIV: Association With Additional Pain Disorders

Peripheral Neuropathy in Patients With HIV: Association With Additional Pain Disorders

Patients with a diagnosis of HIV and peripheral neuropathy often have ≥1 additional pain disorders.

Peripheral Nerve Surgery for Burn Survivors: Improving Outcomes Through Clinician Self-Analysis

Peripheral Nerve Surgery for Burn Survivors: Improving Outcomes Through Clinician Self-Analysis

As survival rates for patients with burns have improved, the need for effective treatments for chronic pain in this population has become more pressing.

Chemotherapy-Induced Peripheral Neuropathy: Mechanism Identified

Chemotherapy-Induced Peripheral Neuropathy: Mechanism Identified

The researchers found that paclitaxel triggers CIPN by altering IP3 receptor phosphorylation and intracellular calcium flux and activating calcium-dependent calpain proteases.

Cryotherapy May Prevent Symptoms of Chemotherapy-Induced Peripheral Neuropathy

Cryotherapy May Prevent Symptoms of Chemotherapy-Induced Peripheral Neuropathy

A recent study evaluated the efficacy of cryotherapy for chemo-induced peripheral neuropathy; study participants wore frozen gloves and socks on the dominant side for 90 minutes, including the entire duration of drug infusion.

Trigeminal Neuralgia Linked to Multiple Sclerosis: Comparing Surgical Interventions

Trigeminal Neuralgia Linked to Multiple Sclerosis: Comparing Surgical Interventions

Radiofrequency rhizotomy and the more expensive stereotactic radio surgery provide immediate pain relief from trigeminal neuralgia associated with multiple sclerosis.

Acupuncture for Chronic Pain Relief in Military Populations

Acupuncture for Chronic Pain Relief in Military Populations

Electrical stimulation and a higher baseline pain score were shown to be associated with a higher chance of improved pain relief with acupuncture.

Neuropathy Associated With Adjuvant Chemotherapy: Characteristics

Neuropathy Associated With Adjuvant Chemotherapy: Characteristics

Chronic pain following adjuvant chemotherapy with docetaxel or oxaliplatin may be solely account for by pure sensory neuropathy.

Neuroinflammation in Neuropathic Pain Indicated by Elevated Levels of Proinflammatory Chemokines in CSF

Neuroinflammation in Neuropathic Pain Indicated by Elevated Levels of Proinflammatory Chemokines in CSF

Patients with neuropathic pain have elevated levels of a set of pro-inflammatory chemokines compared with healthy individuals, suggesting ongoing neuroinflammation.

FDA Approves New Treatment for Diabetic Peripheral Neuropathy, Postherpetic Neuralgia

FDA Approves New Treatment for Diabetic Peripheral Neuropathy, Postherpetic Neuralgia

The FDA has approved Lyrica CR, a once-daily treatment for the management of neuropathic pain associated with diabetic peripheral neuropathy and the management of postherpetic neuralgia.

Opioid, Gabapentin Combo Rx May Increase Mortality Risk

Opioid, Gabapentin Combo Rx May Increase Mortality Risk

Both gabapentin and opioids are commonly prescribed for the treatment of pain, making the likelihood of these two agents being prescribed together high.

Chronic Inflammatory Demyelinating Polyneuropathy: Privigen Gains FDA Approval

Chronic Inflammatory Demyelinating Polyneuropathy: Privigen Gains FDA Approval

Privigen is stabilized with proline, which has been shown to reduce IgG aggregation and dimer formation.

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

Capsaicin 8% Patch Safe for Peripheral Neuropathic Pain

The use of capsaicin 8% patch repeat treatment is well tolerated and may provide effective long-term benefit in patients with peripheral neuropathic pain.

Chemo-Induced Peripheral Neuropathy Risk Reduced With Multivitamin

Chemo-Induced Peripheral Neuropathy Risk Reduced With Multivitamin

Multivitamin use before diagnosis of breast cancer is associated with reduced risk of symptoms of chemotherapy-induced peripheral neuropathy.

Cannabis for Neuropathic Pain: What Evidence Is There?

Cannabis for Neuropathic Pain: What Evidence Is There?

There is currently little conclusive evidence to suggest a benefit of cannabis use for the management of neuropathic pain.

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

Gabapentin, Pregabalin Effective for Burn-Related Pruritus, Neuropathic Pain

The use of gabapentin, pregabalin, or both is effective for reducing pruritus and neuropathic pain in burn survivors.

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

Pregabalin vs Gabapentin for Neuropathic Pain to Achieve Therapeutic Dose

Patients with neuropathic pain are more likely to achieve effective therapeutic dose when treated with pregabalin compared with gabapentin.

Vitamin D Deficiency Associated With Neuropathic Pain in Rheumatoid Arthritis

Vitamin D Deficiency Associated With Neuropathic Pain in Rheumatoid Arthritis

In patients with rheumatoid arthritis, vitamin D deficiency was shown to be associated with increased neuropathic pain.

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

Preemptive Analgesia to Prevent Chronic Postsurgical Pain

Preemptive analgesia seeks to prevent central sensitization and ensuing chronic pain, a concept that has shown promising results in preliminary studies.

Is Nerve Decompression Effective for Restless Leg Syndrome?

Is Nerve Decompression Effective for Restless Leg Syndrome?

Nerve decompression used to treat peripheral neuropathy may improve symptoms of restless leg syndrome.

Intravenous Lidocaine Safe, Effective for Chronic Pain

Intravenous Lidocaine Safe, Effective for Chronic Pain

Lidocaine infusions were shown to provide long-lasting and adequate analgesia in 41% of patients with chronic pain.

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Neuropathic Pain: Assessing Safety, Efficacy of Higher Pregabalin Doses

Patients with neuropathic pain who do not respond to a low dose of pregabalin can benefit from a higher dose.

Long-Term Opioid Therapy Linked to Adverse Effects in Polyneuropathy

Long-Term Opioid Therapy Linked to Adverse Effects in Polyneuropathy

Long-term treatment with opioids is associated with more adverse outcomes in patients with polyneuropathy, including depression, overdose, and opioid dependence.

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