Neonatal Abstinence Syndrome
Methadone may be superior to morphine for reducing hospital length of stay and length of drug treatment in infants with neonatal abstinence syndrome.
Methadone exposure in utero was shown to increase the risk for neonatal abstinence syndrome compared with buprenorphine exposure.
The infants of women taking opioids concomitantly with psychotropic medications were found to have a substantially heightened risk of neonatal drug withdrawal.
In infants with neonatal abstinence syndrome, sublingual buprenorphine reduced the duration of treatment and decreased the length of hospital stay.
Sublingual buprenorphine is associated with shorter duration of treatment than oral morphine for infants with neonatal abstinence syndrome.
The article reviews the epidemiology, clinical features, outcomes, prevention strategies, risk identification and management NAS.
Children with neonatal abstinence syndrome may be more likely to perform poorly in school.
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