Migraine

Pediatric Episodic Syndromes Linked to Migraines: Signs and Symptoms (Part I)

Pediatric Episodic Syndromes Linked to Migraines: Signs and Symptoms (Part I)

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Nearly 10% of pediatric patients with migraines also experience episodic syndromes involving symptoms such as vomiting, vertigo, or gastrointestinal pain.

Onabotulinumtoxin A for Migraine: High Satisfaction, Compliance

Onabotulinumtoxin A for Migraine: High Satisfaction, Compliance

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Most centers follow recommended guidelines for the use of onabotulinumtoxin A in chronic migraine and applied a consistent measure of response to therapy of a 30% to 50% reduction in headache days.

Minimum Headache Duration Requiring Subarachnoid Hemorrhage Evaluation

Minimum Headache Duration Requiring Subarachnoid Hemorrhage Evaluation

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Patients with acute onset of severe headache should undergo diagnostic testing for subarachnoid hemorrhage, a potentially dangerous cause of headache, if the minimum duration of headache is present.

Acupressure Not Effective as Adjunctive Therapy to Sodium Valproate for Chronic Migraine With Aura

Acupressure Not Effective as Adjunctive Therapy to Sodium Valproate for Chronic Migraine With Aura

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Acupressure is not an effective adjunctive therapy to sodium valproate for chronic migraine with aura, but can reduce treatment-associated nausea.

Finding the Link Between Migraine and Cerebral Blood Flow

Finding the Link Between Migraine and Cerebral Blood Flow

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Overall blood flow velocity remains unchanged during migraine headache, although blood flow velocity may be decreased early on in the attack.

Complementary and Alternative Medicine Use low for Migraine Treatment

Complementary and Alternative Medicine Use low for Migraine Treatment

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While some CAM products have shown beneficial effects for migraine treatment, previous studies have not explored reasons for using CAM and the types of CAM used.

Vestibular Migraine Symptoms, Triggers Identified

Vestibular Migraine Symptoms, Triggers Identified

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A retrospective study identified a set of clinical characteristics and triggers of vestibular migraine in the absence of a peripheral etiology for vertigo.

Aimovig Under Review for Migraine Prophylaxis

Aimovig Under Review for Migraine Prophylaxis

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The FDA has accepted for review the Biologics License Application for Aimovig for migraine prophylaxis in patients experiencing more than 4 migraine days per month.

High Headache Frequency Associated With Excessive Daytime Sleepiness

High Headache Frequency Associated With Excessive Daytime Sleepiness

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An association was established between excessive daytime sleepiness and a high frequency of headaches.

Cilostazol Consistently Triggers Migraine Attacks

Cilostazol Consistently Triggers Migraine Attacks

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Cilostazol triggers migraine-like attacks in patients with migraine without aura in a reproducible manner.

Surgical Deactivation of Trigger Sites Leads to Long-Term Migraine Relief

Surgical Deactivation of Trigger Sites Leads to Long-Term Migraine Relief

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Surgical deactivation of trigger sites may be efficacious for reducing occipital-triggered migraine headaches.

Response to Cervical Injections for Pediatric Headache May be due to Placebo Effect

Response to Cervical Injections for Pediatric Headache May be due to Placebo Effect

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Ropivacaine may not be superior to injected saline for the treatment of headache in children.

Allodynia and Pericranial Tenderness Highly Prevalent in Pediatric Patients With Migraine

Allodynia and Pericranial Tenderness Highly Prevalent in Pediatric Patients With Migraine

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Symptoms associated with central sensitization are common in children and adolescents with migraine.

Attachment Insecurity Mediates Anxiety in Pediatric Migraine

Attachment Insecurity Mediates Anxiety in Pediatric Migraine

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Attachment insecurity may amplify anxiety in children and adolescents with migraine without aura.

Hemiplegic Migraine: Leveraging Genetic Susceptibilities to Identify Treatment Targets

Hemiplegic Migraine: Leveraging Genetic Susceptibilities to Identify Treatment Targets

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While migraine is often triggered by environmental factors such as stress, impaired sleep, and menstruation, recent findings have shed light on the significant genetic influence associated with the disorder.

Migraine Research Funding: Where do we Stand?

Migraine Research Funding: Where do we Stand?

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The NINDS welcomes more migraine research grants.

Impact of Allodynia on Acute Migraine Treatment

Impact of Allodynia on Acute Migraine Treatment

The understanding of the mechanisms of allodynia is essential for the treatment of migraine.

Transcutaneous Supraorbital Neurostimulation as Prophylactic Treatment for Chronic Migraine

Transcutaneous Supraorbital Neurostimulation as Prophylactic Treatment for Chronic Migraine

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Transcutaneous supraorbital neurostimulation provides an effective prophylactic treatment for patients with chronic migraine.

Pubertal Hormones: Influence on Migraine in Girls

Pubertal Hormones: Influence on Migraine in Girls

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Mechanisms involved in balancing reproductive hormones in girls may influence the patterns of migraine headache onset.

Connection Between Migraine and Hypertension in Women

Dr Pamela Rist discusses her research in women with migraine and hypertension at the 2017 American Academy of Neurology Annual Meeting in Boston, MA. Scroll to below the video for a full text transcript of Dr Rist's interview.

Arteriovenous Malformations-Related Headache Identification, Treatment

Arteriovenous Malformations-Related Headache Identification, Treatment

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The mechanisms underlying the link between unruptured AVM and headache are unclear, and it is difficult to differentiate AVM-associated headaches with headaches of other origins.

Migraine, Fetal Growth Restriction Associated in Men

Migraine, Fetal Growth Restriction Associated in Men

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Fetal growth restriction is associated with an elevated risk of migraine in adult men, but not women.

Risk for Hypertension in Women With a History of Migraine

Risk for Hypertension in Women With a History of Migraine

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The risk for developing hypertension was slightly higher in women with a history of migraine compared with women who do not have a history of the condition.

Anti-CGRP Receptor Antibody Erenumab Reduces Monthly Migraine Days

Anti-CGRP Receptor Antibody Erenumab Reduces Monthly Migraine Days

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In a phase 3 trial, treatment with erenumab reduced migraine frequency, monthly migraine days, and migraine medication use in patients with episodic migraine.

Dopamine Release Reduced During Acute Migraine

Dopamine Release Reduced During Acute Migraine

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Acute migraine attacks are associated with a reduction in dopamine release.

New Migraine Indication for Qudexy XR

New Migraine Indication for Qudexy XR

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FDA grants 2 supplemental New Drug Applications for Qudexy XR capsules for use as prophylaxis of migraine headache.

Photophobia Linked to Psychiatric Comorbidities in Migraineurs and Controls

Photophobia Linked to Psychiatric Comorbidities in Migraineurs and Controls

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Both patients with migraine and migraine-free control patients with photophobia were found to exhibit higher rates of depression, anxiety, and stress than individuals without photophobia.

Female Reproductive Stages and Migraine

Female Reproductive Stages and Migraine

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The estimated overall prevalence of migraine is 18% in women and 6% in men, and the rate is as high as 37% among women during the reproductive years.

Psychological Factors As Treatment Target in Chronic Migraine

Psychological Factors As Treatment Target in Chronic Migraine

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Psychological factors such as catastrophizing of pain are common in migraine and, along with depression and anxiety, contribute significantly to migraine-related disability.

Pain Acceptance Linked With Reduced Disability, Pain Interference in Migraine

Pain Acceptance Linked With Reduced Disability, Pain Interference in Migraine

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Higher levels of pain acceptance were associated with less headache disability and pain interference in overweight women with migraine.

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