Migraine

Prochlorperazine More Effective Than Ketamine for Treating Headaches in the Emergency Department

Prochlorperazine More Effective Than Ketamine for Treating Headaches in the Emergency Department

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Investigators found that patients receiving prochlorperazine had a greater reduction in headache-related pain compared with patients receiving ketamine.

Migraine Frequency Reduced With Erenumab, Fremanezumab

Migraine Frequency Reduced With Erenumab, Fremanezumab

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Complete results from 2 phase 3 trials examining the effects of 2 humanized monoclonal antibodies in patients with episodic and chronic migraine were published simultaneously.

Patients With Migraine Frequently Revisit the Emergency Department for Headache

Patients With Migraine Frequently Revisit the Emergency Department for Headache

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More than 25% of patients presenting to the emergency department (ED) for migraine typically require subsequent ED revisits for headache within a 6-month period.

Contraceptive Use and the Risk for Ischemic Stroke in Women With Migraine

Contraceptive Use and the Risk for Ischemic Stroke in Women With Migraine

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Consensus statement cautions against the use of hormonal contraceptives in women with migraine, as these medications may be associated with an increased risk for ischemic stroke.

Current and Emerging Behavioral Treatments for Migraine: Expert Q&A

Current and Emerging Behavioral Treatments for Migraine: Expert Q&A

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Some patients with migraines prefer nonpharmacological approaches to treatment and for these patients, evidence-based behavioral treatments may be at least as effective for migraine prophylaxis as medication.

Screening Tool to Predict Risk for Poor Outcomes in Children With Headache

Screening Tool to Predict Risk for Poor Outcomes in Children With Headache

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Use of the 9-item Pediatric Pain Screening Tool may help clinicians identify children with headache who are at risk for poor outcomes, ultimately helping to optimize individualized therapy.

Cerebrospinal Fluid Sodium Concentration May Be Elevated in Patients With Migraine

Cerebrospinal Fluid Sodium Concentration May Be Elevated in Patients With Migraine

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Patients who experience migraines may have higher cerebral sodium concentrations than nonmigraineurs.

Incidental Findings on Brain MRI for Pediatric Headache

Incidental Findings on Brain MRI for Pediatric Headache

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Although a range of incidental findings may be observed on MRI obtained in pediatric headache, they are rarely indicative of a serious underlying condition.

Elevated Interictal Oxytocin Associated With Affective Pain in Chronic Migraine

Elevated Interictal Oxytocin Associated With Affective Pain in Chronic Migraine

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The higher interictal levels of oxytocin observed in patients with chronic migraine compared with unaffected individuals may contribute to the affective component of experimental pain.

Expert's Insights Into Coverage Gap for Cluster Headache Oxygen Therapy

Expert's Insights Into Coverage Gap for Cluster Headache Oxygen Therapy

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A recently published article exposes a gaping hole in the access to an effective first-line therapy for a portion of patients with cluster headache in the United States.

Higher Migraine Frequency Increases Severity of Depression, Anxiety

Higher Migraine Frequency Increases Severity of Depression, Anxiety

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Frequent migraines with or without aura were shown to increase the severity of anxiety and depression.

Migraine-Associated Nausea Improved With Intranasal Sumatriptan

Migraine-Associated Nausea Improved With Intranasal Sumatriptan

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Nasal sumatriptan powder was associated with more favorable nausea outcomes compared with oral sumatriptan tablets in patients with acute migraine.

Migraine in Adults Linked to Childhood Abuse

Migraine in Adults Linked to Childhood Abuse

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Abuse during childhood has a significant association with migraine and maladaptive personality traits in adulthood.

Examining the Link Between Migraine and Gastrointestinal Disorders

Examining the Link Between Migraine and Gastrointestinal Disorders

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A recent study provides a comprehensive summary of the relevant published studies linking migraine and gastrointestinal or related disorders.

Patent Foramen Ovale Closure for Migraine: Weighing Risks and Benefits

Patent Foramen Ovale Closure for Migraine: Weighing Risks and Benefits

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There is a suggested link between migraine and the presence of patent foramen ovale, with the suggestion that PFO closure surgery might be a preventative measure against future migraine attacks, but what are the consequences?

Migraine Frequency Correlated With Depression and Anxiety

Migraine Frequency Correlated With Depression and Anxiety

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The frequency of migraine - with or without aura - may be correlated with score of symptoms of anxiety and depression.

Hydromorphone vs Prochlorperazine/Diphenhydramine for Acute Migraine Pain Relief

Hydromorphone vs Prochlorperazine/Diphenhydramine for Acute Migraine Pain Relief

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A treatment of intravenous hydromorphone was found to provide less pain relief for acute migraine than IV prochlorperazine in patients admitted to the emergency department.

Case Study: Headache, Stiff Neck, Droopy Eyes

Case Study: Headache, Stiff Neck, Droopy Eyes

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A man with a history of hypertension and migraines complains of a headache he has had for approximately 3 days alongside neck stiffness and a fever.

Biologics License Application Submitted for Fremanezumab for Migraine Prevention

Biologics License Application Submitted for Fremanezumab for Migraine Prevention

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Teva announced the submission of a Biologics License Application to the FDA for fremanezumab for the prevention of migraine.

Nasal Sumatriptan Results in Faster Migraine Pain Relief

Nasal Sumatriptan Results in Faster Migraine Pain Relief

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Nasal administration of sumatriptan powder in patients with migraine results in quicker reductions in pain intensity and migraine-related disability compared with oral sumatriptan.

Nurse and Physician Intervention Improves Quality of Life for Migraine Patients

Nurse and Physician Intervention Improves Quality of Life for Migraine Patients

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A multidisciplinary medical approach to headache treatment by physicians and nurses can significantly improve quality of life in patients with migraines.

Using Stress to Predict Risk of Migraine Even Before Predromal Symptoms

Using Stress to Predict Risk of Migraine Even Before Predromal Symptoms

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Among individuals diagnosed with episodic migraines, stressful events can accurately predict an individual's risk of a headache, even before the onset of prodromal symptoms.

Migraine Prevalence, Severity Linked to Higher Altitude

Migraine Prevalence, Severity Linked to Higher Altitude

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People who live at high altitudes may experience increase migraine prevalence, duration, and severity of migraine.

FDA Approves Magnetic Device for Migraine Prevention and Treatment

FDA Approves Magnetic Device for Migraine Prevention and Treatment

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The FDA has cleared the non-invasive SpringTMS device for the acute and prophylactic treatment of migraine headaches.

Galcanezumab Monthly Injections Beneficial in Migraine Pain

Galcanezumab Monthly Injections Beneficial in Migraine Pain

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Monthly galcanezumab injections at 120 mg or 240 mg offer clinical benefit in reducing migraine pain.

PTSD More Likely in Pregnant Women With Migraines

PTSD More Likely in Pregnant Women With Migraines

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Women who are pregnant and have migraines are more likely to have posttraumatic stress disorder (PTSD) than women without migraine.

Lasmiditan Effective in Phase 3 Trial for Acute Migraine

Lasmiditan Effective in Phase 3 Trial for Acute Migraine

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Eli Lily announced positive results from a Phase 3 trial of their first-in-class drug lasmiditan for the acute treatment of migraine.

Migraine Treatment: Are Opioids Overprescribed?

Migraine Treatment: Are Opioids Overprescribed?

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There are nearly as many migraine patients receiving opioids as there are patients receiving level A abortive medications.

Complementary and Integrative Medicine in Migraine and Headache Management

Complementary and Integrative Medicine in Migraine and Headache Management

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Several methods of complementary and integrative medicine bring value and their integration into a headache management plan in the clinical setting empowers patients' healing process.

Pediatric Episodic Syndromes Linked to Migraines: Signs and Symptoms (Part I)

Pediatric Episodic Syndromes Linked to Migraines: Signs and Symptoms (Part I)

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Nearly 10% of pediatric patients with migraines also experience episodic syndromes involving symptoms such as vomiting, vertigo, or gastrointestinal pain.

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