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LUPRON DEPOT-3 MONTH 11.25mg
Anemias
Endometriosis
Miscellaneous Ob/Gyn conditions
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Drug Name:

LUPRON DEPOT-3 MONTH 11.25mg Rx

Generic Name and Formulations:
Leuprolide acetate 11.25mg; depot susp for IM inj; preservative-free.

Company:
AbbVie

Therapeutic Use:

Indications for LUPRON DEPOT-3 MONTH 11.25mg:

Presurgical treatment of patients with anemia due to uterine leiomyomata (fibroids), with iron therapy if iron therapy alone is inadequate.

Adult:

≥18yrs: 11.25mg IM once every 3 months (1 injection). Do not split doses.

Children:

<18yrs: not applicable.

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal contraception during therapy; discontinue if pregnancy occurs. Risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Elderly.

See Also:

LUPRON DEPOT 3.75mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)

Indications for LUPRON DEPOT-3 MONTH 11.25mg:

Endometriosis management, including pain relief and reduction of endometriotic lesions. With norethindrone acetate: for initial management and recurrent symptoms.

Adult:

≥18yrs: 11.25mg IM once every 3 months; treat for up to 6 months (2 injections). May repeat one 6-month cycle; give with norethindrone acetate 5mg daily when retreating. Do not split doses.

Children:

<18yrs: not applicable (unless endometriosis occurs after puberty; see full labeling).

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal methods of contraception during therapy; discontinue if pregnancy occurs. Consider concomitant norethindrone acetate and supplemental calcium with risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Retreatment: not recommended.

See Also:

LUPRON DEPOT 3.75mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)

Indications for LUPRON DEPOT-3 MONTH 11.25mg:

Presurgical treatment of patients with anemia due to uterine leiomyomata (fibroids), with iron therapy if iron therapy alone is inadequate.

Adult:

≥18yrs: 11.25mg IM once every 3 months (1 injection). Do not split doses.

Children:

<18yrs: not applicable.

Contraindications:

Undiagnosed abnormal vaginal bleeding. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Exclude pregnancy before starting; use nonhormonal contraception during therapy; discontinue if pregnancy occurs. Risk factors for decreased bone mineral density (eg, chronic alcohol, tobacco, anticonvulsants, corticosteroids). Missing successive doses may cause breakthrough bleeding or ovulation. Elderly.

See Also:

LUPRON DEPOT 3.75mg

Pharmacological Class:

GnRH analogue.

Adverse Reactions:

Hot flashes, headache, vaginitis, depression, emotional lability, pain, decreased libido, breast changes, amenorrhea, mastodynia, joint disorder, asthenia, GI upset, edema, bone density loss, local reactions, acne, memory disorders, others; rarely: anaphylaxis, asthma, increased serum transaminases or lipids.

How Supplied:

Kit—1 (single-dose syringe w. diluent, supplies)

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