Low Back Pain
Variable and unpredicted perturbations to the spine may lead to increased muscle strength and pain reduction in patients with chronic nonspecific low back pain.
Sacroiliac joint fusion and triangular titanium implants are associated with higher pain relief and greater reductions in disability than conservative management in patients with sacroiliac joint-related chronic low back pain.
NKTR-181 was found to be safe and effective in patients with low back pain.
For patients with discogenic low back pain due to failed back surgery syndrome, dorsal root ganglion stimulation is associated with pain relief.
Pilates may represent an effective therapy for the management of chronic lower back pain.
Yoga improved health outcomes in military veterans with chronic low back pain, including lowering their pain intensity.
Radiofrequency denervation may be ineffective in alleviating chronic low back pain.
The cerebrospinal fluid of patients with vs without intervertebral disc degeneration with and without low back pain was shown to differentially express proteins involved in inflammation and nerve injury.
Yoga was deemed noninferior to physical therapy for the treatment of patients with chronic low back pain.
Patients with low back pain who are depressed are more likely to be prescribed opioids, and to be prescribed higher doses.
Radiofrequency denervation improved chronic low back pain arising from the facet joints.
Long-term, clinically important improvement in chronic low back pain can be achieved with lumbar total disc replacement and multidisciplinary rehabilitation in patients whose low back pain does not respond to conservative therapy.
Repeated magnetic resonance imaging for chronic spine pain does not impact occurrence of surgical treatment or interval changes.
Spinal manipulative therapy is associated with moderate improvements in pain and function in patients with acute low back pain.
Clobazam is more effective than placebo in reducing low back pain.
A novel method of short-term percutaneous peripheral nerve stimulation is useful for producing pain relief and reducing medication use among patients with chronic low back pain.
Spinal cord stimulation using precision approach via 3D neural targeting shows superior efficacy in treating chronic axial low back pain compared with a traditional approach relying on a trial-and-error method to achieve desired paresthesia.
Psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain.
Early use of physical therapy for new low back pain in older adults is not associated with less subsequent back pain-specific health care utilization.
The ACP developed the guideline from randomized, controlled trials and systematic reviews published through April 2015 that focused on noninvasive pharmacologic and nonpharmacologic treatments for low back pain.
For patients with acute low back pain, the combination of diazepam plus naproxen does not improve functional outcomes or pain compared with naproxen use alone.
For individuals presenting with a primary complaint of mechanical LBP, prescriptive treatment of the hips seems beneficial, in addition to treatment of the lumbar spine.
Weather conditions generally do not influence pain.
Obesity-related measures are not associated with the risk of developing chronic low-back pain.
Yoga only led to moderate improvements compared with exercise or no exercise interventions in patients with low back pain.
The benefit-risk profile of oxycodone/naloxone was found to be noninferior compared to tapentadol, and oxycodone/naloxone demonstrated superior analgesic efficacy.
"The intra-articular PRP injection is an effective treatment modality in low back pain involving SIJ," the authors write.
According to Dr Mackey, successful enactment of the NPS will allow clinicians to "treat chronic pain as the chronic disease [they] know it to be, and as the public health crisis that [they] know it is."
"Ultimately, the goal is to turn our clinics into research laboratories where every single patient is characterized," noted Dr Mackey.
Results showed a significant link between serum vitamin C concentrations and the prevalence of low back pain.
Clinical Pain Advisor Articles
- Brain Plasticity in Patients With Complex Regional Pain Syndrome
- Perturbation-Based Rehabilitation Effective for Chronic Low Back Pain
- IBS-Associated Chronic Pain: Formulation of Core Diagnostic Criteria
- Cannabis Use Associated With Relationship Between Pain and Negative Affect
- Fluoroscopically Guided Sacroiliac Interventions: Appropriate Use Criteria
- Cannabis Use Associated With Aberrant Drug Behaviors
- Walgreens to Carry Naloxone in All Pharmacies to Combat Drug Abuse
- Independent Pharmacies Expanding Services Available to Patients
- Ketamine Exhibits Effective Pain Relief for Refractory Headaches
- Pain In Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach
- Naproxen Plus Muscle Relaxants vs Naproxen Monotherapy for Low Back Pain
- Pain Processing: Examining the Role of Oxytocin
- Short- vs Long-Acting Opioids for Osteoarthritis Pain
- Extended-Release Naltrexone Injections Reduce Opioid Dependence
- Depressive Symptoms in Medical Interns Increased With Work-Family Conflicts