Intradiscal Biacuplasty Improves Outcomes in LBP

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At 6 months, crossover subjects responded similarly to the originally treated group.
At 6 months, crossover subjects responded similarly to the originally treated group.

HealthDay News -- For patients with chronic low back pain (LBP) of discogenic origin, 12-month outcomes are superior for intradiscal biacuplasty plus conservative medical management (IDB+CMM) versus CMM alone, according to a study presented at the annual meeting of the American Academy of Pain Medicine, held from Feb. 18 to 21 in Palm Springs, California.

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Michael Gofeld, MD, from the University of Toronto, and colleagues examined the 12-month outcomes for patients with chronic LBP of discogenic origin treated with IDB+CMM. Sixty-three patients were randomized to receive IDB+CMM (29 patients) or CMM alone (34 patients). At 6 months post randomization, CMM-alone participants were allowed to cross over to IDB+CMM (25 patients).

The researchers found that for the original IDB+CMM group, the mean outcome measures were each statistically and clinically superior to baseline values at 12 months. At 12 months, a minimum of 50% of the IDB+CMM group reported a continued response to treatment. The IDB+CMM group experienced a mean visual analog scale change of −2.2 from baseline, 14-point decrease in Oswestry Disability Index from baseline, 1.7-point improvement in patient global impression of change, and 0.13-point improvement in quality of life index. 

At 6 months, crossover subjects responded similarly to the originally treated group.

"The results were not only statistically significant but -- more importantly -- clinically meaningful," Gofeld said in a statement. "Without addressing disc pathology, pain and function do not get better."

Reference

Gofeld M, Desai M, Kapural L, Petersohn J, Vallejo R, Menzes R, et al. Abstract #123. Long-Term Results (12-Months) of a Prospective, Multicenter, Open-Label Clinical Trial Comparing Intradiscal Biacuplasty to Conventional Medical Management for Discogenic Lumbar Back Pain. Presented at: AAP 2016. February 16-20, 2016; Sacramento, California.

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